急性呼吸窘迫綜合征(ARDS)是(shi)一種(zhong)以進行性呼吸困難和頑固性低氧血癥(zheng)為主要特征的(de)(de)急性呼吸衰竭,其實質上是(shi)多(duo)種(zhong)原因所引起的(de)(de)急性肺損傷。日(ri)前(qian),廣東(dong)省廣州市中(zhong)(zhong)醫院吳偉勝醫師等運(yun)用中(zhong)(zhong)藥通瘀逐水灌腸(chang)液灌腸(chang)結合西醫治療(liao)ARDS50例,取得明顯(xian)療(liao)效(xiao)。
研(yan)究(jiu)者采用(yong)(yong)西醫常規治(zhi)(zhi)(zhi)療(liao),如(ru)特別監護、吸痰、吸氧;對適(shi)應證(zheng)患者采用(yong)(yong)機(ji)械通氣(有創或無創);積極(ji)治(zhi)(zhi)(zhi)療(liao)基(ji)礎疾(ji)病,如(ru)骨(gu)折的(de)(de)固定(ding),休克的(de)(de)糾(jiu)正,抗生素治(zhi)(zhi)(zhi)療(liao)嚴重感染或手術(shu)治(zhi)(zhi)(zhi)療(liao)等(deng);對適(shi)應證(zheng)者適(shi)當(dang)應用(yong)(yong)糖皮質(zhi)激(ji)素;維(wei)持(chi)適(shi)當(dang)的(de)(de)體液(ye)、電(dian)解質(zhi)平衡(heng)以及營(ying)養支持(chi)。在此基(ji)礎上,加用(yong)(yong)中藥通瘀(yu)逐水(shui)灌(guan)腸液(ye)治(zhi)(zhi)(zhi)療(liao)。方(fang)藥為大黃、枳實各12克,厚樸、水(shui)牛角(jiao)、丹參、赤(chi)芍、生地黃各15克,桃仁10克,水(shui)蛭末、甘遂末各1.5克。每(mei)天(tian)1劑,水(shui)煎(jian)取藥液(ye)300毫升,保留(liu)灌(guan)腸。10天(tian)為1個療(liao)程。
根據該病臨(lin)床所見的呼吸(xi)困難、張口(kou)抬肩、咳逆喘促(cu)、鼻翼煽(shan)動、胸悶(men)紫(zi)紺、尿少便(bian)秘(mi)等癥狀,可將ARDS歸(gui)屬中(zhong)醫學(xue)喘證范疇。吳偉(wei)勝等認為,ARDS的發生(sheng)(sheng)與肺(fei)氣(qi)壅(yong)滯相(xiang)(xiang)(xiang)關。病機(ji)關鍵(jian)為水(shui)(shui)熱壅(yong)肺(fei)、閉阻三焦、氣(qi)滯血(xue)瘀(yu)(yu)(yu)、邪實正(zheng)虛。由于(yu)“肺(fei)與大腸(chang)(chang)相(xiang)(xiang)(xiang)表里”,肺(fei)氣(qi)不(bu)通(tong)(tong),濁(zhuo)氣(qi)不(bu)能(neng)從下而(er)出(chu),則(ze)腹滿痞脹(zhang);胃(wei)腸(chang)(chang)氣(qi)機(ji)壅(yong)塞,濁(zhuo)氣(qi)上迫(po)于(yu)肺(fei),愈使肺(fei)氣(qi)塞窒郁閉,喘促(cu)更甚。如(ru)此惡性循(xun)環,引(yin)起上喘下滿的病理變化(hua)。故采用(yong)(yong)通(tong)(tong)瘀(yu)(yu)(yu)逐(zhu)水(shui)(shui)灌(guan)腸(chang)(chang)液灌(guan)腸(chang)(chang)以瀉熱逐(zhu)水(shui)(shui)、通(tong)(tong)瘀(yu)(yu)(yu)攻(gong)(gong)下為主(zhu),使水(shui)(shui)、瘀(yu)(yu)(yu)、熱之(zhi)邪從下而(er)出(chu),胃(wei)腸(chang)(chang)郁閉之(zhi)氣(qi)機(ji)得(de)(de)以宣暢,肺(fei)之(zhi)呼吸(xi)困難亦隨之(zhi)減輕,瘀(yu)(yu)(yu)血(xue)表現隨之(zhi)好轉。方中(zhong)以大黃、甘(gan)遂相(xiang)(xiang)(xiang)配瀉熱逐(zhu)水(shui)(shui)、通(tong)(tong)利(li)大腸(chang)(chang);枳(zhi)實、厚樸行氣(qi)以助化(hua)瘀(yu)(yu)(yu)、利(li)水(shui)(shui);水(shui)(shui)牛角(jiao)、丹參、赤(chi)芍、桃(tao)仁、生(sheng)(sheng)地黃、水(shui)(shui)蛭相(xiang)(xiang)(xiang)伍,清熱解毒、活血(xue)化(hua)瘀(yu)(yu)(yu)。諸藥合用(yong)(yong),共奏瀉熱逐(zhu)水(shui)(shui)、行氣(qi)通(tong)(tong)瘀(yu)(yu)(yu)、攻(gong)(gong)下解毒之(zhi)功效(xiao)。而(er)中(zhong)藥灌(guan)腸(chang)(chang),便(bian)于(yu)施藥,用(yong)(yong)藥安全,方法簡便(bian),特(te)別是對于(yu)ARDS患者(zhe)來說,避免(mian)了口(kou)服湯劑容易(yi)引(yin)起嘔(ou)吐、胃(wei)內(nei)容物(wu)反流所致(zhi)再次肺(fei)損傷。此外,灌(guan)腸(chang)(chang)治療吸(xi)收快,起效(xiao)快,生(sheng)(sheng)物(wu)利(li)用(yong)(yong)度高(gao),值得(de)(de)臨(lin)床推廣(guang)應用(yong)(yong)。
本文地址://n85e38t.cn/zhongyizatan/78199.html.
聲明: 我們(men)致力于保護作者版(ban)權,注重分享,被刊用文章因無法(fa)核實(shi)真(zhen)實(shi)出處(chu),未能及時(shi)(shi)與(yu)作者取得聯系,或有版(ban)權異(yi)議的,請聯系管(guan)(guan)理(li)員(yuan),我們(men)會立(li)即處(chu)理(li),本站部分文字與(yu)圖(tu)片資(zi)源(yuan)來自于網絡,轉載是出于傳(chuan)遞更多(duo)信息之目的,若有來源(yuan)標注錯誤或侵犯了您的合法(fa)權益(yi),請立(li)即通(tong)知我們(men)(管(guan)(guan)理(li)員(yuan)郵箱(xiang):),情況屬實(shi),我們(men)會第(di)一時(shi)(shi)間(jian)予以刪除,并同時(shi)(shi)向您表(biao)示(shi)歉意(yi),謝謝!