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朱砂安神丸有哪些有哪些作用和功效

生(sheng)活百事通 2023-09-20 22:03:40

朱砂安神丸

《內外傷辨惑論》

【組成(cheng)】 朱砂 五錢(qian)(qian)(15g)另(ling)研,水(shui)飛(fei)為(wei)衣 黃(huang)連(lian) 去須,凈,酒洗 六錢(qian)(qian)(18g) 炙甘草(cao) 五錢(qian)(qian)半(16.5g) 生地黃(huang) 一錢(qian)(qian)半(4.5g) 當歸 二錢(qian)(qian)半(7.5g)

【用(yong)(yong)法(fa)】 上藥除朱砂(sha)(sha)外,四味(wei)共(gong)為(wei)(wei)細(xi)(xi)末,湯(tang)(tang)浸蒸餅為(wei)(wei)丸(wan),如黍米(mi)大(da)。以朱砂(sha)(sha)為(wei)(wei)衣(yi),每(mei)服十(shi)五丸(wan)或二十(shi)丸(wan)(3~4g),津(jin)唾咽之,食(shi)后(現代用(yong)(yong)法(fa):上藥研末為(wei)(wei)丸(wan),水(shui)(shui)蜜丸(wan)每(mei)次6g,蜜丸(wan)每(mei)次9g,臨(lin)睡前溫開水(shui)(shui)送服;亦可作湯(tang)(tang)劑,用(yong)(yong)量按原(yuan)方(fang)比例酌(zhuo)減,朱砂(sha)(sha)研細(xi)(xi)末水(shui)(shui)飛,以藥湯(tang)(tang)送服)。

【功用】 鎮心安(an)神(shen),清熱養(yang)血。

【主治(zhi)】 心火亢(kang)盛,陰(yin)血不足(zu)證(zheng)。失眠多(duo)夢,驚悸怔(zheng)忡(chong),心煩神亂,或胸(xiong)中懊 (忄(xin)農),舌尖紅,脈細數。

【方(fang)(fang)解】 本方(fang)(fang)所治(zhi)之(zhi)(zhi)證(zheng),乃因心(xin)(xin)(xin)火(huo)亢盛,灼(zhuo)傷陰(yin)(yin)血(xue)所致(zhi)。心(xin)(xin)(xin)火(huo)亢盛,則(ze)(ze)心(xin)(xin)(xin)神(shen)被擾,陰(yin)(yin)血(xue)不足,則(ze)(ze)心(xin)(xin)(xin)神(shen)失養(yang),故見失眠多(duo)夢(meng),驚(jing)悸(ji)怔忡,心(xin)(xin)(xin)煩(fan)等癥(zheng);舌紅(hong),脈(mo)細數,是心(xin)(xin)(xin)火(huo)盛而陰(yin)(yin)血(xue)虛之(zhi)(zhi)征。治(zhi)當瀉其(qi)亢盛之(zhi)(zhi)火(huo),補(bu)其(qi)陰(yin)(yin)血(xue)之(zhi)(zhi)虛而安(an)神(shen)。方(fang)(fang)中(zhong)朱砂(sha)甘(gan)(gan)寒質(zhi)(zhi)重(zhong),專(zhuan)入心(xin)(xin)(xin)經,寒能清熱,重(zhong)可鎮怯(qie),既能重(zhong)鎮安(an)神(shen),又(you)可清心(xin)(xin)(xin)火(huo),治(zhi)標之(zhi)(zhi)中(zhong)兼能治(zhi)本,是為君(jun)藥。黃(huang)連(lian)苦(ku)(ku)(ku)寒,入心(xin)(xin)(xin)經,清心(xin)(xin)(xin)瀉火(huo),以(yi)(yi)(yi)除(chu)煩(fan)熱,為臣。君(jun)、臣相伍(wu),重(zhong)鎮以(yi)(yi)(yi)安(an)神(shen),清心(xin)(xin)(xin)以(yi)(yi)(yi)除(chu)煩(fan),以(yi)(yi)(yi)收(shou)瀉火(huo)安(an)神(shen)之(zhi)(zhi)功。佐以(yi)(yi)(yi)生(sheng)地黃(huang)之(zhi)(zhi)甘(gan)(gan)苦(ku)(ku)(ku)寒,以(yi)(yi)(yi)滋陰(yin)(yin)清熱;當歸之(zhi)(zhi)辛甘(gan)(gan)溫潤,以(yi)(yi)(yi)補(bu)血(xue),合生(sheng)地黃(huang)滋補(bu)陰(yin)(yin)血(xue)以(yi)(yi)(yi)養(yang)心(xin)(xin)(xin)。使以(yi)(yi)(yi)炙甘(gan)(gan)草調(diao)藥和中(zhong),以(yi)(yi)(yi)防黃(huang)連(lian)之(zhi)(zhi)苦(ku)(ku)(ku)寒、朱砂(sha)之(zhi)(zhi)質(zhi)(zhi)重(zhong)礙(ai)胃。合而用(yong)之(zhi)(zhi),標本兼治(zhi),清中(zhong)有(you)養(yang),使心(xin)(xin)(xin)火(huo)得清,陰(yin)(yin)血(xue)得充,心(xin)(xin)(xin)神(shen)得養(yang),則(ze)(ze)神(shen)志(zhi)安(an)定(ding),是以(yi)(yi)(yi)“安(an)神(shen)”名(ming)之(zhi)(zhi)。

【運用】

1.辨證要(yao)點:本方是治療心(xin)火亢(kang)盛,陰血不(bu)足(zu)而致神志不(bu)安的(de)常用(yong)方。臨床應用(yong)以失眠,驚(jing)悸(ji),舌(she)紅,脈細(xi)數(shu)為(wei)辨證要(yao)點。方中(zhong)朱(zhu)砂含硫(liu)化汞(gong),不(bu)宜多服、久服,以防引起(qi)汞(gong)中(zhong)毒;陰虛或(huo)脾弱(ruo)者不(bu)宜服。

2.加(jia)減法:若(ruo)胸(xiong)中(zhong)煩(fan)(fan)熱較甚,加(jia)山梔仁、蓮子心(xin)(xin)以增(zeng)強清心(xin)(xin)除煩(fan)(fan)之力;兼驚(jing)恐,宜加(jia)生(sheng)龍(long)骨、生(sheng)牡(mu)蠣以鎮驚(jing)安神;失眠多夢者,可加(jia)酸棗仁、柏子仁以養心(xin)(xin)安神。

3.現代(dai)運用:本(ben)方常用于(yu)神經(jing)衰弱(ruo)所(suo)致的失眠、心悸、健忘,精神憂郁癥引起(qi)的神志恍惚,以及心臟(zang)早搏所(suo)致的心悸、怔(zheng)忡等屬于(yu)心火亢盛,陰血不足者。

 【附方】

磁(ci)(ci)朱丸(wan)(《備急千金要方》原名神曲丸(wan)) 神曲 四兩(liang)(120g) 磁(ci)(ci)石 二兩(liang)(60g) 光(guang)明砂一(yi)兩(liang)(30g) 右(you)三(san)味末之,煉蜜(mi)為丸(wan),如(ru)梧子,飲服三(san)丸(wan)(2g),日三(san)服。功用:益陰(yin)明目,重鎮安神。主(zhu)治(zhi):心腎不(bu)交,耳鳴耳聾,心悸失眠,亦治(zhi)癲癇。

本方與朱砂(sha)安神(shen)丸均用朱砂(sha)重鎮安神(shen),以治(zhi)失眠(mian),心(xin)(xin)(xin)悸,多(duo)夢等(deng)癥。朱砂(sha)安神(shen)丸配黃連瀉(xie)火,生(sheng)地(di)、當歸補(bu)陰血,長(chang)于(yu)清心(xin)(xin)(xin)瀉(xie)火,滋(zi)陰養血,主(zhu)(zhu)治(zhi)心(xin)(xin)(xin)火亢(kang)盛,陰血不足(zu)之失眠(mian),心(xin)(xin)(xin)悸;磁(ci)朱丸中配磁(ci)石益陰潛(qian)陽(yang),長(chang)于(yu)潛(qian)陽(yang)明(ming)目(mu),交(jiao)通心(xin)(xin)(xin)腎,主(zhu)(zhu)治(zhi)腎陰不足(zu),心(xin)(xin)(xin)陽(yang)偏亢(kang),心(xin)(xin)(xin)腎不交(jiao)之失眠(mian)心(xin)(xin)(xin)悸,耳鳴(ming)耳聾,視(shi)物昏花等(deng)。

【文獻摘要】

1.原方主治

《內外傷辨(bian)惑論(lun)》卷(juan)中(zhong): “如(ru)心(xin)浮(fu)氣亂,以朱(zhu)砂安(an)神丸鎮(zhen)固之(zhi)。”

 2.方論選錄

唐宗海《血證論》卷7:“朱(zhu)砂之(zhi)(zhi)重(zhong)以鎮怯,黃(huang)(huang)連(lian)(lian)之(zhi)(zhi)苦以清熱,當歸之(zhi)(zhi)辛以噓血,更(geng)取(qu)甘(gan)草之(zhi)(zhi)甘(gan),以制黃(huang)(huang)連(lian)(lian)之(zhi)(zhi)太過,地黃(huang)(huang)之(zhi)(zhi)潤以助當歸所不(bu)及(ji)。合之(zhi)(zhi)養血清火,安鎮心(xin)神,怔忡(chong)心(xin)煩不(bu)寐之(zhi)(zhi)癥,可以治之(zhi)(zhi)。”

吳謙(qian),等《醫宗金鑒·刪補名醫方論》卷1錄葉仲堅:“朱砂具(ju)光明之(zhi)(zhi)(zhi)(zhi)體,色(se)赤(chi)通(tong)心,重(zhong)以(yi)(yi)鎮怯,寒能勝熱(re),甘(gan)以(yi)(yi)生津,抑陰(yin)火之(zhi)(zhi)(zhi)(zhi)浮游,以(yi)(yi)養上焦之(zhi)(zhi)(zhi)(zhi)元氣,為(wei)安神(shen)之(zhi)(zhi)(zhi)(zhi)第一品。心若熱(re),配(pei)黃連之(zhi)(zhi)(zhi)(zhi)苦(ku)寒,瀉心熱(re)也(ye),更佐(zuo)甘(gan)草之(zhi)(zhi)(zhi)(zhi)甘(gan)以(yi)(yi)瀉之(zhi)(zhi)(zhi)(zhi)。心主血,用當(dang)歸之(zhi)(zhi)(zhi)(zhi)甘(gan)溫(wen),歸心血也(ye),更佐(zuo)地黃之(zhi)(zhi)(zhi)(zhi)寒以(yi)(yi)補之(zhi)(zhi)(zhi)(zhi)。心血足(zu)則肝得(de)所(suo)藏,而魂(hun)自(zi)安,心熱(re)解則肺得(de)其職,而魄自(zi)寧(ning)也(ye)。”

【臨床報道】

孫(sun)氏治療心(xin)(xin)(xin)(xin)(xin)臟(zang)早(zao)(zao)(zao)搏(bo)54例(li)(li)(li)(li)(li),其發病(bing)(bing)原因(yin)為冠心(xin)(xin)(xin)(xin)(xin)病(bing)(bing)者(zhe)14例(li)(li)(li)(li)(li),病(bing)(bing)毒(du)性心(xin)(xin)(xin)(xin)(xin)肌炎(yan)者(zhe)11例(li)(li)(li)(li)(li),風(feng)濕(shi)性心(xin)(xin)(xin)(xin)(xin)臟(zang)病(bing)(bing)者(zhe)7例(li)(li)(li)(li)(li),肺(fei)心(xin)(xin)(xin)(xin)(xin)病(bing)(bing)者(zhe)6例(li)(li)(li)(li)(li),心(xin)(xin)(xin)(xin)(xin)肌病(bing)(bing)者(zhe)4例(li)(li)(li)(li)(li),未(wei)發現心(xin)(xin)(xin)(xin)(xin)臟(zang)有問題(ti)者(zhe)12例(li)(li)(li)(li)(li);中(zhong)醫(yi)辨證屬于氣血虧(kui)虛者(zhe)18例(li)(li)(li)(li)(li),陰(yin)虛火旺者(zhe)24例(li)(li)(li)(li)(li),氣陰(yin)虧(kui)虛兼有心(xin)(xin)(xin)(xin)(xin)血瘀阻者(zhe)12例(li)(li)(li)(li)(li)。用朱(zhu)砂安(an)神丸為主(zhu),每(mei)次1丸,每(mei)日2次,首次加倍,溫開(kai)水送服。用藥(yao)1周為1療程。經(jing)用藥(yao)1個(ge)療程者(zhe)16例(li)(li)(li)(li)(li),2個(ge)療程者(zhe)22例(li)(li)(li)(li)(li),3個(ge)療程者(zhe)12例(li)(li)(li)(li)(li)。結(jie)果(guo):心(xin)(xin)(xin)(xin)(xin)電圖示早(zao)(zao)(zao)搏(bo)消(xiao)失者(zhe)為顯(xian)效,計26例(li)(li)(li)(li)(li);早(zao)(zao)(zao)搏(bo)減(jian)少,心(xin)(xin)(xin)(xin)(xin)悸、頭暈(yun)、心(xin)(xin)(xin)(xin)(xin)臟(zang)停跳、失眠等(deng)癥(zheng)狀明(ming)顯(xian)減(jian)輕者(zhe)為有效,計22例(li)(li)(li)(li)(li);心(xin)(xin)(xin)(xin)(xin)電圖無(wu)改變,癥(zheng)狀改善不明(ming)顯(xian)為無(wu)效,計6例(li)(li)(li)(li)(li)。[孫(sun)國(guo),等(deng).以朱(zhu)砂安(an)神丸為主(zhu)治療心(xin)(xin)(xin)(xin)(xin)臟(zang)過早(zao)(zao)(zao)搏(bo)動54例(li)(li)(li)(li)(li)觀察。河(he)北(bei)中(zhong)醫(yi) 1993;15(4):9]

【實驗研究】

實(shi)驗研(yan)(yan)究表(biao)明,朱(zhu)(zhu)砂(sha)安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)、朱(zhu)(zhu)砂(sha)、去(qu)朱(zhu)(zhu)砂(sha)之安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)均有(you)對(dui)抗氯仿-腎上腺素和(he)草烏注射液所致心律失常的(de)(de)作(zuo)(zuo)用,其作(zuo)(zuo)用強(qiang)度為,朱(zhu)(zhu)砂(sha)安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)>朱(zhu)(zhu)砂(sha)>去(qu)朱(zhu)(zhu)砂(sha)之安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan),尤其是(shi)朱(zhu)(zhu)砂(sha)安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)的(de)(de)作(zuo)(zuo)用遠強(qiang)于去(qu)朱(zhu)(zhu)砂(sha)之安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)。[李鐘文(wen),等.朱(zhu)(zhu)砂(sha)及朱(zhu)(zhu)砂(sha)安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)鎮心安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)功效(xiao)的(de)(de)研(yan)(yan)究。中國(guo)中藥雜志(zhi) 1993;18(7):436]采用多(duo)導睡(shui)眠(mian)(mian)描(miao)記技術研(yan)(yan)究朱(zhu)(zhu)砂(sha)安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)對(dui)貓(mao)睡(shui)眠(mian)(mian)-覺(jue)醒(xing)的(de)(de)影響。表(biao)明朱(zhu)(zhu)砂(sha)安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)能明顯的(de)(de)縮短清醒(xing)期,延長慢(man)波睡(shui)眠(mian)(mian)I期及總(zong)睡(shui)眠(mian)(mian)時間,且能縮短慢(man)波睡(shui)眠(mian)(mian)I期-Ⅱ期及異相睡(shui)眠(mian)(mian)的(de)(de)潛(qian)伏期,能翻(fan)轉對(dui)氯苯丙(bing)氨(an)酸(suan)的(de)(de)睡(shui)眠(mian)(mian)剝(bo)奪(duo)效(xiao)應(ying)。[孫兵(bing),等.朱(zhu)(zhu)砂(sha)安(an)(an)(an)神(shen)(shen)(shen)(shen)(shen)(shen)丸(wan)(wan)藥理作(zuo)(zuo)用的(de)(de)實(shi)驗研(yan)(yan)究。中成藥 1995;17(7):30]

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