據中國醫(yi)藥報訊 日前，由(you)第四(si)軍醫(yi)大學西(xi)京醫(yi)院完成(cheng)的(de)一項(xiang)陜西(xi)省中醫(yi)藥管理局科研基(ji)(ji)金項(xiang)目表明，血(xue)竭(jie)乙酸乙酯提取物具有顯著的(de)促進角質形成(cheng)細胞增殖作用，為進一步研究血(xue)竭(jie)促進傷(shang)口愈合的(de)機制奠定了基(ji)(ji)礎(chu)。
血(xue)(xue)(xue)(xue)竭(jie)(jie)在我國(guo)被作為名貴中(zhong)藥(yao)(yao)使用(yong)已(yi)有(you)(you)1500多(duo)年(nian)的(de)(de)(de)歷史，它是來源于熱帶棕櫚科黃藤屬及(ji)百合(he)(he)科龍(long)血(xue)(xue)(xue)(xue)樹(shu)屬的(de)(de)(de)10多(duo)種植(zhi)物(wu)的(de)(de)(de)樹(shu)脂類(lei)中(zhong)藥(yao)(yao)，成(cheng)分復雜，主要含有(you)(you)血(xue)(xue)(xue)(xue)竭(jie)(jie)素、血(xue)(xue)(xue)(xue)竭(jie)(jie)紅素等黃酮類(lei)化合(he)(he)物(wu)及(ji)三(san)萜(tie)類(lei)化合(he)(he)物(wu)等成(cheng)分。臨床應用(yong)血(xue)(xue)(xue)(xue)竭(jie)(jie)及(ji)含有(you)(you)血(xue)(xue)(xue)(xue)竭(jie)(jie)的(de)(de)(de)生肌藥(yao)(yao)物(wu)治療(liao)難(nan)愈性創面(mian)(mian)(mian)，具有(you)(you)確切的(de)(de)(de)療(liao)效。以往的(de)(de)(de)研究多(duo)從活血(xue)(xue)(xue)(xue)化瘀、改善創面(mian)(mian)(mian)血(xue)(xue)(xue)(xue)供等作用(yong)入(ru)手探討血(xue)(xue)(xue)(xue)竭(jie)(jie)促進(jin)(jin)創面(mian)(mian)(mian)愈合(he)(he)的(de)(de)(de)機制(zhi)，但至今未求得各方公認的(de)(de)(de)合(he)(he)理的(de)(de)(de)解釋。表皮(pi)覆蓋是創面(mian)(mian)(mian)愈合(he)(he)的(de)(de)(de)關(guan)鍵步(bu)驟(zou)，而角質形(xing)成(cheng)細(xi)胞占表皮(pi)構(gou)成(cheng)的(de)(de)(de)90%，國(guo)內已(yi)有(you)(you)人報道血(xue)(xue)(xue)(xue)竭(jie)(jie)提取物(wu)能促進(jin)(jin)角質形(xing)成(cheng)細(xi)胞游走，但血(xue)(xue)(xue)(xue)竭(jie)(jie)是否(fou)有(you)(you)促進(jin)(jin)角質形(xing)成(cheng)細(xi)胞增(zeng)殖(zhi)的(de)(de)(de)作用(yong)目前還未見報道。
西京醫(yi)院(yuan)的(de)科研人員將血竭經過氯仿、乙酸乙酯(zhi)、乙醇回流提取得到三種(zhong)提取液，并(bing)(bing)以之分(fen)別作用于(yu)體外培(pei)養(yang)的(de)角質形成細胞(bao)(bao)。以噻唑藍（MTT）法檢(jian)測不同血竭提取物在不同濃(nong)度以及不同時間點對體外培(pei)養(yang)的(de)角質形成細胞(bao)(bao)的(de)增殖的(de)影(ying)響，并(bing)(bing)繪(hui)制最(zui)適濃(nong)度下(xia)細胞(bao)(bao)生長曲線(xian)；利用流式細胞(bao)(bao)儀分(fen)析最(zui)適濃(nong)度培(pei)養(yang)條件下(xia)角質形成細胞(bao)(bao)的(de)細胞(bao)(bao)周期(qi)變化的(de)。
結果(guo)表明，各(ge)種濃度的氯仿(fang)提取(qu)物(wu)及乙(yi)(yi)醇(chun)提取(qu)物(wu)，對(dui)(dui)角質形成細胞增殖的影響與對(dui)(dui)照組（DMEM干粉(fen)培養基）相比，均(jun)無(wu)顯著性(xing)差異。乙(yi)(yi)酸(suan)乙(yi)(yi)酯(zhi)提取(qu)物(wu)在(zai)濃度為0.0625、0.125、0.25、0.5、1.0、2.0毫克/毫升(sheng)(sheng)時(shi)，能明顯促進角質形成細胞增殖，其中在(zai)0.0625毫克/毫升(sheng)(sheng)～0.5毫克/毫升(sheng)(sheng)濃度范圍內，呈劑量依賴(lai)關系，且在(zai)0.5毫克/毫升(sheng)(sheng)濃度值時(shi)促進作(zuo)用(yong)最顯著。
科研(yan)人員介紹，傷口愈合(he)需要經(jing)過傷口收(shou)縮(suo)、肉芽組織填充(chong)與再上皮(pi)化(hua)三個步驟。其(qi)中，再上皮(pi)化(hua)一(yi)(yi)般(ban)要經(jing)過角質(zhi)(zhi)形(xing)(xing)成細(xi)(xi)胞激活、游(you)走(zou)(zou)、增(zeng)殖(zhi)及基膜的(de)(de)修(xiu)復等過程(cheng)(cheng)(cheng)。加快角質(zhi)(zhi)形(xing)(xing)成細(xi)(xi)胞增(zeng)殖(zhi)的(de)(de)速度可以縮(suo)短傷口愈合(he)中再上皮(pi)化(hua)的(de)(de)進程(cheng)(cheng)(cheng)。已(yi)有研(yan)究發現，血(xue)竭(jie)對角質(zhi)(zhi)形(xing)(xing)成細(xi)(xi)胞具有促(cu)進游(you)走(zou)(zou)的(de)(de)作(zuo)用。本研(yan)究結果表(biao)明(ming)，在濃度為(wei)0.5毫(hao)(hao)克/毫(hao)(hao)升時，血(xue)竭(jie)乙(yi)酸乙(yi)酯(zhi)提取物(wu)可顯著(zhu)促(cu)進角質(zhi)(zhi)形(xing)(xing)成細(xi)(xi)胞增(zeng)殖(zhi)。因此，血(xue)竭(jie)對于(yu)再上皮(pi)化(hua)過程(cheng)(cheng)(cheng)中角質(zhi)(zhi)形(xing)(xing)成細(xi)(xi)胞的(de)(de)游(you)走(zou)(zou)、增(zeng)殖(zhi)均有顯著(zhu)促(cu)進作(zuo)用，這應(ying)是其(qi)促(cu)進創面愈合(he)的(de)(de)機制之一(yi)(yi)。
目錄(lu)1拼(pin)音(yin)(yin)2概述3《中醫方(fang)劑雙解(jie)與臨(lin)床(chuang)》方(fang)之復(fu)明(ming)湯 3.1組成(cheng)3.2用(yong)(yong)法3.3功(gong)用(yong)(yong)主治3.4方(fang)解(jie)3.5運用(yong)(yong)3.6現代適(shi)應證 3.6.1小兒重癥感染后并發失明(ming) 3.7復(fu)明(ming)湯的藥理作用(yong)(yong) 3.7.1對病原微生物的影響(xiang)3.7.2對神經、內分泌(mi)系(xi)統(tong)功(gong)能的影響(xiang)3.7.3對心血管系(xi)統(tong)功(gong)能的影響(xiang)3.7.4對消化系(xi)統(tong)功(gong)能的影響(xiang)3.7.5對免(mian)疫系(xi)統(tong)功(gong)能的影響(xiang)3.7.6抗炎及抗氧化損傷作用(yong)(yong)3.7.7其他4參考資料附(fu)：1古籍中的復(fu)明(ming)湯 1拼(pin)音(yin)(yin) fù míng tāng
2概述 復(fu)明(ming)湯此方的組成為丹參10g、川芎(xiong)3g、紅花4g、?蟲3g、當歸(gui)4g、血(xue)竭3g、白(bai)術10g、陳皮6g、焦三仙(xian)各(ge)6g。具(ju)有滋陰清熱(re)，養(yang)血(xue)補血(xue)，活血(xue)化瘀，健脾和胃(wei)之功效。主治(zhi)小兒暴盲(mang)。
3《中醫(yi)方(fang)(fang)劑雙解(jie)與臨床(chuang)》方(fang)(fang)之復明(ming)湯 該(gai)方(fang)(fang)劑有(you)一定(ding)(ding)的抗(kang)病原(yuan)微(wei)生(sheng)物、抗(kang)炎抗(kang)氧化(hua)作用、免疫增(zeng)強(qiang)及調解(jie)作用，特別是對心腦血(xue)管(guan)及血(xue)流變學具有(you)十(shi)分顯著和(he)突(tu)出的作用，因(yin)此對重癥感染(ran)后并發失明(ming)、耳聾、偏(pian)癱必定(ding)(ding)有(you)十(shi)分積極的療效，并已得到臨床(chuang)驗證。但是，一定(ding)(ding)要結合現(xian)代醫(yi)學抗(kang)生(sheng)素方(fang)(fang)法(fa)(fa)、液體方(fang)(fang)法(fa)(fa)、營養(yang)支(zhi)持療法(fa)(fa)。[1]
1．本方劑治(zhi)療重癥(zheng)感(gan)(gan)染(ran)后并發雙目或單目失(shi)明，常于重癥(zheng)顱內感(gan)(gan)染(ran)后或感(gan)(gan)染(ran)性休(xiu)克后發生，臨床以上發熱、萎(wei)靡(mi)、失(shi)明、脈細弱為證(zheng)治(zhi)要(yao)點；同時多伴(ban)失(shi)語、偏癱，常與有(you)效抗生素配合(he)應用。
2．感(gan)染重癥(zheng)或未徹底控制者(zhe)可(ke)酌加黃連(lian)、黃柏，休(xiu)克或循環(huan)不良者(zhe)酌加人參、附子。
3.6.1小兒重癥感染(ran)后(hou)并發(fa)(fa)(fa)失(shi)明(ming)(ming)(ming)(ming) 小兒重癥感染(ran)后(hou)并發(fa)(fa)(fa)失(shi)明(ming)(ming)(ming)(ming)以(yi)學(xue)齡前(qian)兒童多(duo)見。從(cong)失(shi)明(ming)(ming)(ming)(ming)的(de)(de)(de)類型(xing)看，病(bing)(bing)變(bian)可(ke)(ke)發(fa)(fa)(fa)生(sheng)在(zai)(zai)(zai)(zai)視(shi)(shi)(shi)網膜、視(shi)(shi)(shi)神經(jing)(jing)、視(shi)(shi)(shi)交叉(cha)(cha)、視(shi)(shi)(shi)中(zhong)樞(shu)(shu)（外側(ce)膝狀體、視(shi)(shi)(shi)放射、皮質視(shi)(shi)(shi)中(zhong)樞(shu)(shu)）等(deng)視(shi)(shi)(shi)路(lu)的(de)(de)(de)任(ren)何(he)(he)一(yi)部(bu)(bu)(bu)分(fen)，但(dan)以(yi)紋狀區皮質視(shi)(shi)(shi)中(zhong)樞(shu)(shu)病(bing)(bing)變(bian)所致(zhi)(zhi)者(zhe)為(wei)多(duo)。同(tong)時絕大(da)部(bu)(bu)(bu)分(fen)伴有失(shi)語和偏癱(tan)，說明(ming)(ming)(ming)(ming)大(da)腦(nao)(nao)(nao)(nao)(nao)(nao)病(bing)(bing)變(bian)部(bu)(bu)(bu)位(wei)比(bi)較(jiao)廣泛。從(cong)臨床角度(du)分(fen)析(xi)其(qi)(qi)病(bing)(bing)因機制有如(ru)下4方面(mian)：①感染(ran)細(xi)(xi)菌、病(bing)(bing)毒及(ji)(ji)其(qi)(qi)毒素(su)(su)(su)入顱后(hou)，一(yi)方面(mian)引(yin)(yin)起(qi)腦(nao)(nao)(nao)(nao)(nao)(nao)膜彌(mi)漫性(xing)(xing)(xing)(xing)(xing)充血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)、滲出，大(da)量的(de)(de)(de)漿液(ye)(ye)纖維(wei)蛋(dan)白性(xing)(xing)(xing)(xing)(xing)滲出物聚集在(zai)(zai)(zai)(zai)顱底、大(da)腦(nao)(nao)(nao)(nao)(nao)(nao)腳以(yi)及(ji)(ji)視(shi)(shi)(shi)交叉(cha)(cha)處擠(ji)壓(ya)(ya)視(shi)(shi)(shi)神經(jing)(jing)及(ji)(ji)視(shi)(shi)(shi)交叉(cha)(cha)，便可(ke)(ke)發(fa)(fa)(fa)生(sheng)一(yi)側(ce)全(quan)(quan)盲和雙顳側(ce)偏盲；另一(yi)方面(mian)細(xi)(xi)菌、毒素(su)(su)(su)、病(bing)(bing)毒以(yi)及(ji)(ji)感染(ran)產(chan)生(sheng)的(de)(de)(de)大(da)量自由(you)基可(ke)(ke)致(zhi)(zhi)腦(nao)(nao)(nao)(nao)(nao)(nao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)痙攣、內(nei)皮細(xi)(xi)胞破壞，造(zao)成腦(nao)(nao)(nao)(nao)(nao)(nao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)炎性(xing)(xing)(xing)(xing)(xing)狹窄，甚而(er)閉塞，從(cong)而(er)使(shi)視(shi)(shi)(shi)路(lu)相(xiang)(xiang)應(ying)(ying)部(bu)(bu)(bu)位(wei)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)，特(te)別(bie)是(shi)紋狀區皮質視(shi)(shi)(shi)中(zhong)樞(shu)(shu)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)即(ji)可(ke)(ke)導致(zhi)(zhi)相(xiang)(xiang)應(ying)(ying)病(bing)(bing)變(bian)支配處失(shi)明(ming)(ming)(ming)(ming)。②驚(jing)(jing)厥與(yu)(yu)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)、缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)性(xing)(xing)(xing)(xing)(xing)腦(nao)(nao)(nao)(nao)(nao)(nao)病(bing)(bing)，驚(jing)(jing)厥時腦(nao)(nao)(nao)(nao)(nao)(nao)耗氧(yang)(yang)(yang)(yang)增(zeng)(zeng)加(jia)(jia)3倍，腦(nao)(nao)(nao)(nao)(nao)(nao)代(dai)謝(xie)增(zeng)(zeng)加(jia)(jia)2～4倍，腦(nao)(nao)(nao)(nao)(nao)(nao)供(gong)(gong)氧(yang)(yang)(yang)(yang)量也明(ming)(ming)(ming)(ming)顯下降。嚴重缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)可(ke)(ke)導致(zhi)(zhi)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)、缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)性(xing)(xing)(xing)(xing)(xing)腦(nao)(nao)(nao)(nao)(nao)(nao)病(bing)(bing)，血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)內(nei)皮細(xi)(xi)胞受損(sun)、腫脹(zhang)、管(guan)腔狹窄，同(tong)時使(shi)Ⅷ因子(zi)相(xiang)(xiang)關的(de)(de)(de)因子(zi)增(zeng)(zeng)加(jia)(jia)，可(ke)(ke)發(fa)(fa)(fa)生(sheng)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)及(ji)(ji)播散性(xing)(xing)(xing)(xing)(xing)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)內(nei)凝(ning)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)；缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)、缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)又可(ke)(ke)導致(zhi)(zhi)細(xi)(xi)胞內(nei)Ca2+濃度(du)異常升(sheng)高(gao)，經(jing)(jing)過一(yi)系列作(zuo)用引(yin)(yin)起(qi)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)素(su)(su)(su)A2大(da)量生(sheng)成，血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)素(su)(su)(su)A2可(ke)(ke)收縮(suo)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)，從(cong)而(er)使(shi)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小板(ban)產(chan)生(sheng)強烈聚集而(er)引(yin)(yin)起(qi)廣泛的(de)(de)(de)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)形成。血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)栓(shuan)(shuan)塞在(zai)(zai)(zai)(zai)視(shi)(shi)(shi)路(lu)的(de)(de)(de)任(ren)何(he)(he)部(bu)(bu)(bu)位(wei)，均(jun)可(ke)(ke)引(yin)(yin)起(qi)相(xiang)(xiang)應(ying)(ying)的(de)(de)(de)失(shi)明(ming)(ming)(ming)(ming)。③休克(ke)與(yu)(yu)腦(nao)(nao)(nao)(nao)(nao)(nao)水(shui)腫，各種顱內(nei)感染(ran)腦(nao)(nao)(nao)(nao)(nao)(nao)細(xi)(xi)胞均(jun)可(ke)(ke)使(shi)腦(nao)(nao)(nao)(nao)(nao)(nao)細(xi)(xi)胞腫脹(zhang)變(bian)性(xing)(xing)(xing)(xing)(xing)或(huo)壞死，以(yi)致(zhi)(zhi)腦(nao)(nao)(nao)(nao)(nao)(nao)水(shui)腫，如(ru)果發(fa)(fa)(fa)生(sheng)腦(nao)(nao)(nao)(nao)(nao)(nao)脊(ji)液(ye)(ye)分(fen)泌(mi)異常或(huo)循(xun)環障(zhang)(zhang)礙便出現腦(nao)(nao)(nao)(nao)(nao)(nao)積水(shui)；休克(ke)、中(zhong)毒型(xing)菌痢(li)均(jun)可(ke)(ke)誘發(fa)(fa)(fa)腦(nao)(nao)(nao)(nao)(nao)(nao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)、缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)，缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)、缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)時腦(nao)(nao)(nao)(nao)(nao)(nao)內(nei)興奮性(xing)(xing)(xing)(xing)(xing)氨基酸、β內(nei)啡肽(tai)、氧(yang)(yang)(yang)(yang)自由(you)基增(zeng)(zeng)加(jia)(jia)，三(san)(san)者(zhe)又進一(yi)步加(jia)(jia)重腦(nao)(nao)(nao)(nao)(nao)(nao)水(shui)腫。腦(nao)(nao)(nao)(nao)(nao)(nao)水(shui)腫一(yi)方面(mian)擠(ji)壓(ya)(ya)視(shi)(shi)(shi)神經(jing)(jing)管(guan)，造(zao)成視(shi)(shi)(shi) *** 水(shui)腫，擠(ji)壓(ya)(ya)視(shi)(shi)(shi)交叉(cha)(cha)使(shi)該(gai)處神經(jing)(jing)供(gong)(gong)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)供(gong)(gong)氧(yang)(yang)(yang)(yang)不(bu)足，腦(nao)(nao)(nao)(nao)(nao)(nao)內(nei)動(dong)、靜脈(mo)受壓(ya)(ya)變(bian)窄誘發(fa)(fa)(fa)腦(nao)(nao)(nao)(nao)(nao)(nao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)痙攣，加(jia)(jia)重腦(nao)(nao)(nao)(nao)(nao)(nao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)、缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)，形成惡性(xing)(xing)(xing)(xing)(xing)循(xun)環，使(shi)腦(nao)(nao)(nao)(nao)(nao)(nao)組(zu)織變(bian)性(xing)(xing)(xing)(xing)(xing)，若發(fa)(fa)(fa)生(sheng)在(zai)(zai)(zai)(zai)視(shi)(shi)(shi)路(lu)的(de)(de)(de)任(ren)何(he)(he)部(bu)(bu)(bu)位(wei)均(jun)可(ke)(ke)誘發(fa)(fa)(fa)相(xiang)(xiang)應(ying)(ying)的(de)(de)(de)失(shi)明(ming)(ming)(ming)(ming)。④代(dai)謝(xie)紊(wen)亂，如(ru)酸中(zhong)毒、低(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)鈉(na)、低(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)鈣、低(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)糖(tang)，這些可(ke)(ke)以(yi)是(shi)上述病(bing)(bing)因的(de)(de)(de)結果，又可(ke)(ke)是(shi)其(qi)(qi)誘發(fa)(fa)(fa)因素(su)(su)(su)，特(te)別(bie)是(shi)重癥感染(ran)患(huan)者(zhe)兒長期不(bu)能進食，液(ye)(ye)體及(ji)(ji)熱量供(gong)(gong)給不(bu)足，加(jia)(jia)之(zhi)高(gao)熱、驚(jing)(jing)厥代(dai)謝(xie)增(zeng)(zeng)加(jia)(jia)等(deng)必(bi)然(ran)導致(zhi)(zhi)低(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)糖(tang)，在(zai)(zai)(zai)(zai)缺(que)(que)(que)(que)氧(yang)(yang)(yang)(yang)情況下，糖(tang)不(bu)能全(quan)(quan)部(bu)(bu)(bu)進入三(san)(san)羧酸循(xun)環，腦(nao)(nao)(nao)(nao)(nao)(nao)能量供(gong)(gong)給不(bu)足，必(bi)然(ran)導致(zhi)(zhi)腦(nao)(nao)(nao)(nao)(nao)(nao)細(xi)(xi)胞功能障(zhang)(zhang)礙，如(ru)果發(fa)(fa)(fa)生(sheng)在(zai)(zai)(zai)(zai)視(shi)(shi)(shi)路(lu)的(de)(de)(de)任(ren)何(he)(he)部(bu)(bu)(bu)位(wei)，均(jun)可(ke)(ke)引(yin)(yin)起(qi)失(shi)明(ming)(ming)(ming)(ming)。
3.7.1對(dui)(dui)(dui)病(bing)原(yuan)微生物(wu)的(de)(de)影(ying)響(xiang) 君(jun)(jun)藥丹(dan)參及(ji)(ji)其(qi)所含(han)丹(dan)參酮對(dui)(dui)(dui)金黃色(se)葡(pu)(pu)萄(tao)(tao)球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、大腸(chang)(chang)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、變(bian)形(xing)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、痢(li)(li)疾(ji)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、傷寒(han)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)以及(ji)(ji)耐藥菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)均(jun)有(you)較強的(de)(de)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)；對(dui)(dui)(dui)人型(xing)結核桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、霍(huo)亂弧菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)也(ye)能(neng)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)其(qi)生長，同時對(dui)(dui)(dui)奧杜(du)盎芽(ya)孢癬(xian)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、星形(xing)奴卡(ka)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)皮(pi)(pi)膚(fu)(fu)真(zhen)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)也(ye)有(you)不同程度的(de)(de)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)。川芎對(dui)(dui)(dui)大腸(chang)(chang)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、痢(li)(li)疾(ji)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、變(bian)形(xing)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、銅(tong)綠假(jia)(jia)單胞桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、傷寒(han)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、副傷寒(han)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)多(duo)種革蘭(lan)氏(shi)陰性(xing)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)均(jun)有(you)明顯的(de)(de)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)，對(dui)(dui)(dui)多(duo)種皮(pi)(pi)膚(fu)(fu)致(zhi)病(bing)性(xing)真(zhen)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)也(ye)有(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)。君(jun)(jun)藥紅(hong)花能(neng)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)變(bian)形(xing)鏈球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)附著能(neng)力(li)，使菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)斑形(xing)成量減(jian)少，細菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)總(zong)蛋白(bai)(bai)下(xia)降。當歸煎劑對(dui)(dui)(dui)大腸(chang)(chang)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、痢(li)(li)疾(ji)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、傷寒(han)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、白(bai)(bai)喉(hou)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、金黃色(se)葡(pu)(pu)萄(tao)(tao)球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、銅(tong)綠假(jia)(jia)單胞桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)均(jun)有(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)。佐藥生地(di)水浸劑對(dui)(dui)(dui)須瘡癬(xian)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、石膏樣(yang)小(xiao)芽(ya)孢癬(xian)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、羊毛狀小(xiao)芽(ya)孢癬(xian)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)多(duo)種真(zhen)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)均(jun)有(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)。血竭(jie)對(dui)(dui)(dui)金黃色(se)及(ji)(ji)白(bai)(bai)色(se)、檸檬(meng)色(se)葡(pu)(pu)萄(tao)(tao)球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)，奈氏(shi)球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)，大腸(chang)(chang)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)，傷寒(han)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)，銅(tong)綠假(jia)(jia)單胞桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)，乙型(xing)鏈球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)，白(bai)(bai)喉(hou)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)，福氏(shi)痢(li)(li)疾(ji)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)均(jun)有(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)，對(dui)(dui)(dui)絮狀表皮(pi)(pi)癬(xian)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、許蘭(lan)毛癬(xian)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、斷發毛癬(xian)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)多(duo)種皮(pi)(pi)膚(fu)(fu)真(zhen)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)也(ye)有(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)；血竭(jie)所含(han)血竭(jie)紅(hong)素對(dui)(dui)(dui)包皮(pi)(pi)垢(gou)分(fen)枝桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)及(ji)(ji)白(bai)(bai)色(se)念珠菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)也(ye)有(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)。使藥白(bai)(bai)術水煎劑對(dui)(dui)(dui)絮狀表皮(pi)(pi)癬(xian)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、星形(xing)奴卡(ka)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、金黃色(se)葡(pu)(pu)萄(tao)(tao)球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、溶血性(xing)鏈球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、腦膜(mo)炎雙(shuang)球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、枯草桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)均(jun)有(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)。陳皮(pi)(pi)對(dui)(dui)(dui)葡(pu)(pu)萄(tao)(tao)球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)及(ji)(ji)霉菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)有(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)(zhi)作(zuo)用(yong)(yong)。山楂對(dui)(dui)(dui)痢(li)(li)疾(ji)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、變(bian)形(xing)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、大腸(chang)(chang)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)等(deng)均(jun)有(you)較強的(de)(de)抑(yi)(yi)(yi)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)作(zuo)用(yong)(yong)；山楂原(yuan)液對(dui)(dui)(dui)大腸(chang)(chang)桿(gan)(gan)(gan)(gan)(gan)(gan)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)、金黃色(se)葡(pu)(pu)萄(tao)(tao)球(qiu)(qiu)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)有(you)殺菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)作(zuo)用(yong)(yong)。大麥芽(ya)胍堿A、B有(you)抗真(zhen)菌(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)(jun)作(zuo)用(yong)(yong)。
以(yi)上可以(yi)看出，該(gai)方劑有10味藥(yao)有不同范圍、不同程度的(de)抗病(bing)原微生物作(zuo)用，這對于控制(zhi)原發疾病(bing)的(de)感染十分重要，此(ci)即(ji)中醫的(de)“清熱”作(zuo)用。
3.7.2對(dui)神(shen)(shen)經(jing)(jing)、內分泌系(xi)統(tong)功(gong)能(neng)(neng)(neng)的(de)(de)(de)(de)(de)(de)(de)影響 君藥(yao)(yao)丹(dan)(dan)參注射液(ye)(ye)對(dui)腦(nao)(nao)(nao)(nao)(nao)(nao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)再(zai)灌(guan)注損(sun)(sun)傷(shang)(shang)有(you)(you)預防和治療作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，能(neng)(neng)(neng)使(shi)(shi)(shi)梗(geng)死(si)體(ti)積明(ming)顯(xian)縮小(xiao)和減(jian)(jian)輕；丹(dan)(dan)參能(neng)(neng)(neng)降(jiang)(jiang)(jiang)低(di)腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)中(zhong)TXA2的(de)(de)(de)(de)(de)(de)(de)生(sheng)成(cheng)，抑(yi)制(zhi)(zhi)(zhi)(zhi)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)再(zai)灌(guan)注腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)興奮(fen)性(xing)(xing)(xing)(xing)氨(an)基酸(suan)釋(shi)放(fang)，改善(shan)腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)微(wei)循(xun)環(huan)，對(dui)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)性(xing)(xing)(xing)(xing)腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)有(you)(you)顯(xian)著(zhu)(zhu)(zhu)保(bao)(bao)護(hu)(hu)(hu)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，明(ming)顯(xian)降(jiang)(jiang)(jiang)低(di)腦(nao)(nao)(nao)(nao)(nao)(nao)水(shui)腫(zhong)，使(shi)(shi)(shi)腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)內線粒體(ti)、粗(cu)面內質網等超(chao)微(wei)結構(gou)的(de)(de)(de)(de)(de)(de)(de)病理(li)改善(shan)明(ming)顯(xian)減(jian)(jian)輕；同時丹(dan)(dan)參能(neng)(neng)(neng)抑(yi)制(zhi)(zhi)(zhi)(zhi)丘腦(nao)(nao)(nao)(nao)(nao)(nao)后(hou)核內臟放(fang)電，具有(you)(you)一定的(de)(de)(de)(de)(de)(de)(de)鎮(zhen)痛、鎮(zhen)靜(jing)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)。川芎(xiong)(xiong)所(suo)(suo)含(han)主要成(cheng)分川芎(xiong)(xiong)嗪(qin)可迅速(su)透過血(xue)(xue)(xue)(xue)(xue)(xue)(xue)腦(nao)(nao)(nao)(nao)(nao)(nao)屏(ping)障(zhang)，擴(kuo)(kuo)張(zhang)(zhang)腦(nao)(nao)(nao)(nao)(nao)(nao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管，改善(shan)微(wei)循(xun)環(huan)，增加(jia)腦(nao)(nao)(nao)(nao)(nao)(nao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)流量(liang)；川芎(xiong)(xiong)嗪(qin)能(neng)(neng)(neng)提高(gao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)時腦(nao)(nao)(nao)(nao)(nao)(nao)線粒體(ti)膜(mo)的(de)(de)(de)(de)(de)(de)(de)流動性(xing)(xing)(xing)(xing)，對(dui)腦(nao)(nao)(nao)(nao)(nao)(nao)細胞(bao)膜(mo)Ca2+Mg2+ATP酶活(huo)性(xing)(xing)(xing)(xing)有(you)(you)保(bao)(bao)護(hu)(hu)(hu)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，能(neng)(neng)(neng)降(jiang)(jiang)(jiang)低(di)腦(nao)(nao)(nao)(nao)(nao)(nao)細胞(bao)內Ca2+超(chao)載(zai)；川芎(xiong)(xiong)所(suo)(suo)含(han)阿魏酸(suan)能(neng)(neng)(neng)降(jiang)(jiang)(jiang)低(di)腦(nao)(nao)(nao)(nao)(nao)(nao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)時MDA含(han)量(liang)，增加(jia)SOD及GSHPx活(huo)性(xing)(xing)(xing)(xing)，具有(you)(you)顯(xian)著(zhu)(zhu)(zhu)抗(kang)氧化損(sun)(sun)傷(shang)(shang)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)；同時川芎(xiong)(xiong)嗪(qin)注射液(ye)(ye)能(neng)(neng)(neng)顯(xian)著(zhu)(zhu)(zhu)改善(shan)腦(nao)(nao)(nao)(nao)(nao)(nao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)后(hou)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)漿及腦(nao)(nao)(nao)(nao)(nao)(nao)脊液(ye)(ye)中(zhong)強啡肽AI13樣免(mian)疫(yi)活(huo)性(xing)(xing)(xing)(xing)物質含(han)量(liang)變化，減(jian)(jian)輕腦(nao)(nao)(nao)(nao)(nao)(nao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)性(xing)(xing)(xing)(xing)損(sun)(sun)害(hai)和神(shen)(shen)經(jing)(jing)系(xi)統(tong)功(gong)能(neng)(neng)(neng)障(zhang)礙，明(ming)顯(xian)抑(yi)制(zhi)(zhi)(zhi)(zhi)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)后(hou)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)漿β血(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓球蛋(dan)白(bai)（βTG）、血(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)板因子4（PF4）和TXB2的(de)(de)(de)(de)(de)(de)(de)升高(gao)。紅花能(neng)(neng)(neng)減(jian)(jian)輕腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)中(zhong)單胺類(lei)神(shen)(shen)經(jing)(jing)遞質的(de)(de)(de)(de)(de)(de)(de)代謝紊亂，使(shi)(shi)(shi)下降(jiang)(jiang)(jiang)的(de)(de)(de)(de)(de)(de)(de)神(shen)(shen)經(jing)(jing)遞質恢復(fu)(fu)正常，其(qi)所(suo)(suo)含(han)紅花黃色素(su)能(neng)(neng)(neng)保(bao)(bao)護(hu)(hu)(hu)神(shen)(shen)經(jing)(jing)元免(mian)受損(sun)(sun)傷(shang)(shang)，同時具有(you)(you)鎮(zhen)靜(jing)、鎮(zhen)痛和抗(kang)驚厥作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，對(dui)腦(nao)(nao)(nao)(nao)(nao)(nao)急性(xing)(xing)(xing)(xing)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)性(xing)(xing)(xing)(xing)損(sun)(sun)傷(shang)(shang)能(neng)(neng)(neng)減(jian)(jian)輕其(qi)病理(li)損(sun)(sun)害(hai)，使(shi)(shi)(shi)腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)內核糖(tang)核酸(suan)、三磷酸(suan)腺苷、琥珀酸(suan)脫氨(an)酸(suan)等接近正常，并可迅速(su)使(shi)(shi)(shi)異(yi)常的(de)(de)(de)(de)(de)(de)(de)腦(nao)(nao)(nao)(nao)(nao)(nao)電圖恢復(fu)(fu)正常；還(huan)具有(you)(you)擴(kuo)(kuo)張(zhang)(zhang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管，改善(shan)微(wei)循(xun)環(huan)，防止血(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓形成(cheng)的(de)(de)(de)(de)(de)(de)(de)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)；當歸(gui)注射液(ye)(ye)可加(jia)快腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)的(de)(de)(de)(de)(de)(de)(de)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)液(ye)(ye)循(xun)環(huan)，改善(shan)神(shen)(shen)經(jing)(jing)元代謝，減(jian)(jian)少腦(nao)(nao)(nao)(nao)(nao)(nao)梗(geng)死(si)面積，促(cu)進腦(nao)(nao)(nao)(nao)(nao)(nao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)損(sun)(sun)傷(shang)(shang)后(hou)神(shen)(shen)經(jing)(jing)生(sheng)長和修復(fu)(fu)相關(guan)(guan)蛋(dan)白(bai)cyelnD1及GAP43，促(cu)進神(shen)(shen)經(jing)(jing)細胞(bao)黏附分子及促(cu)微(wei)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管相關(guan)(guan)蛋(dan)白(bai)（MAPZ）的(de)(de)(de)(de)(de)(de)(de)表(biao)述(shu)，促(cu)進腦(nao)(nao)(nao)(nao)(nao)(nao)細胞(bao)再(zai)生(sheng)和再(zai)支配，減(jian)(jian)少腦(nao)(nao)(nao)(nao)(nao)(nao)細胞(bao)凋亡(wang)的(de)(de)(de)(de)(de)(de)(de)發(fa)生(sheng)，同時通過促(cu)進bclz的(de)(de)(de)(de)(de)(de)(de)表(biao)達(da)抑(yi)制(zhi)(zhi)(zhi)(zhi)半暗帶的(de)(de)(de)(de)(de)(de)(de)細胞(bao)凋亡(wang)的(de)(de)(de)(de)(de)(de)(de)產(chan)生(sheng)。臣藥(yao)(yao)生(sheng)地水(shui)提液(ye)(ye)能(neng)(neng)(neng)顯(xian)著(zhu)(zhu)(zhu)提高(gao)腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)中(zhong)SOD活(huo)力，氯仿提取液(ye)(ye)能(neng)(neng)(neng)降(jiang)(jiang)(jiang)低(di)腦(nao)(nao)(nao)(nao)(nao)(nao)組織(zhi)中(zhong)MDA含(han)量(liang)。生(sheng)地所(suo)(suo)含(han)低(di)聚糖(tang)對(dui)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)糖(tang)有(you)(you)調節(jie)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，使(shi)(shi)(shi)高(gao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓患者血(xue)(xue)(xue)(xue)(xue)(xue)(xue)糖(tang)降(jiang)(jiang)(jiang)低(di)；同時生(sheng)地水(shui)煎劑有(you)(you)抗(kang)甲狀腺素(su)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，還(huan)有(you)(you)顯(xian)著(zhu)(zhu)(zhu)的(de)(de)(de)(de)(de)(de)(de)鎮(zhen)靜(jing)、催眠作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，能(neng)(neng)(neng)促(cu)進垂體(ti)－腎(shen)(shen)上(shang)腺皮質系(xi)統(tong)功(gong)能(neng)(neng)(neng)，對(dui)抗(kang)地塞米松對(dui)垂體(ti)－腎(shen)(shen)上(shang)腺皮質系(xi)統(tong)的(de)(de)(de)(de)(de)(de)(de)抑(yi)制(zhi)(zhi)(zhi)(zhi)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)。血(xue)(xue)(xue)(xue)(xue)(xue)(xue)竭能(neng)(neng)(neng)提高(gao)纖維蛋(dan)白(bai)溶解酶的(de)(de)(de)(de)(de)(de)(de)活(huo)性(xing)(xing)(xing)(xing)，促(cu)進纖溶活(huo)性(xing)(xing)(xing)(xing)，降(jiang)(jiang)(jiang)低(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)黏度，具有(you)(you)溶栓、防栓作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，對(dui)腦(nao)(nao)(nao)(nao)(nao)(nao)栓塞有(you)(you)治療作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)。佐(zuo)藥(yao)(yao)白(bai)術揮發(fa)油具有(you)(you)鎮(zhen)靜(jing)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)，其(qi)所(suo)(suo)含(han)白(bai)術糖(tang)復(fu)(fu)合物具有(you)(you)降(jiang)(jiang)(jiang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)糖(tang)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)。山楂醇提取物有(you)(you)鎮(zhen)靜(jing)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)。麥(mai)芽(ya)所(suo)(suo)含(han)麥(mai)芽(ya)酚可有(you)(you)效保(bao)(bao)護(hu)(hu)(hu)活(huo)性(xing)(xing)(xing)(xing)氧對(dui)神(shen)(shen)經(jing)(jing)細胞(bao)的(de)(de)(de)(de)(de)(de)(de)氧化損(sun)(sun)傷(shang)(shang)，維持神(shen)(shen)經(jing)(jing)細胞(bao)的(de)(de)(de)(de)(de)(de)(de)正常生(sheng)理(li)功(gong)能(neng)(neng)(neng)。麥(mai)芽(ya)還(huan)有(you)(you)降(jiang)(jiang)(jiang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)糖(tang)作(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)。
從以(yi)上可(ke)以(yi)看出該方劑有(you)10味藥對(dui)神經(jing)、內(nei)分泌系統(tong)有(you)積(ji)極影響，尤(you)以(yi)君、臣(chen)各藥作(zuo)用顯著。除產生(sheng)鎮靜、鎮痛作(zuo)用外，關(guan)(guan)鍵是能改善腦循(xun)環，抗腦血(xue)栓，防腦梗死(si)，對(dui)缺血(xue)再(zai)灌注腦組織進行保護(hu)，修復調節，這對(dui)重(zhong)癥(zheng)感染(ran)并發失明(ming)、偏癱(tan)、聾啞小兒的治療是關(guan)(guan)鍵。同時其調節內(nei)分泌功能也對(dui)本病(bing)十分有(you)益(yi)。
3.7.3對(dui)(dui)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)系(xi)統功能(neng)(neng)(neng)(neng)(neng)的(de)(de)(de)(de)(de)(de)(de)(de)影響(xiang) 君(jun)藥丹(dan)參(can)能(neng)(neng)(neng)(neng)(neng)擴(kuo)(kuo)(kuo)(kuo)張冠(guan)狀(zhuang)(zhuang)動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)，增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)營(ying)養性(xing)(xing)(xing)(xing)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)流(liu)(liu)(liu)，對(dui)(dui)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)垂體(ti)(ti)(ti)后葉素(su)(su)(su)(su)引起(qi)的(de)(de)(de)(de)(de)(de)(de)(de)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)，丹(dan)參(can)素(su)(su)(su)(su)、丹(dan)參(can)酮ⅡA、黃(huang)(huang)酸(suan)鈉均能(neng)(neng)(neng)(neng)(neng)擴(kuo)(kuo)(kuo)(kuo)張心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)臟側支血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)，改(gai)善缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)區(qu)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)流(liu)(liu)(liu)量(liang)(liang)(liang)(liang)；同(tong)(tong)(tong)時(shi)(shi)(shi)(shi)(shi)丹(dan)參(can)能(neng)(neng)(neng)(neng)(neng)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)自由(you)基(ji)(ji)，明(ming)顯(xian)降(jiang)(jiang)低(di)(di)(di)(di)急性(xing)(xing)(xing)(xing)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)時(shi)(shi)(shi)(shi)(shi)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)MDA含(han)(han)量(liang)(liang)(liang)(liang)，提(ti)(ti)(ti)(ti)高(gao)(gao)(gao)SOD活(huo)力，抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)脂(zhi)質過氧(yang)化(hua)(hua)(hua)(hua)反應(ying)；丹(dan)參(can)還(huan)(huan)能(neng)(neng)(neng)(neng)(neng)擴(kuo)(kuo)(kuo)(kuo)張外(wai)周(zhou)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)，減(jian)(jian)(jian)(jian)輕(qing)(qing)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)臟后負荷，減(jian)(jian)(jian)(jian)慢心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)率；降(jiang)(jiang)低(di)(di)(di)(di)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)耗(hao)(hao)氧(yang)量(liang)(liang)(liang)(liang)；丹(dan)參(can)對(dui)(dui)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)鈣通道(dao)阻(zu)(zu)(zu)滯(zhi)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，防(fang)(fang)止(zhi)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)外(wai)Ca2+內(nei)流(liu)(liu)(liu)，對(dui)(dui)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)高(gao)(gao)(gao)濃度Ca2+對(dui)(dui)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)的(de)(de)(de)(de)(de)(de)(de)(de)損(sun)(sun)害作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，因(yin)此具(ju)(ju)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)保護心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)和抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，能(neng)(neng)(neng)(neng)(neng)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)效(xiao)縮(suo)(suo)(suo)(suo)(suo)小(xiao)(xiao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)再灌(guan)注(zhu)(zhu)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)梗(geng)死體(ti)(ti)(ti)積(ji)(ji)；丹(dan)參(can)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)對(dui)(dui)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)和防(fang)(fang)止(zhi)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)室纖(xian)顫的(de)(de)(de)(de)(de)(de)(de)(de)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；擴(kuo)(kuo)(kuo)(kuo)張外(wai)周(zhou)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)、降(jiang)(jiang)低(di)(di)(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)，降(jiang)(jiang)低(di)(di)(di)(di)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)內(nei)膽固醇(chun)的(de)(de)(de)(de)(de)(de)(de)(de)合(he)成(cheng)(cheng)，降(jiang)(jiang)低(di)(di)(di)(di)氧(yang)化(hua)(hua)(hua)(hua)脂(zhi)蛋白對(dui)(dui)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)的(de)(de)(de)(de)(de)(de)(de)(de)毒性(xing)(xing)(xing)(xing)反應(ying)，從(cong)(cong)而(er)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)硬化(hua)(hua)(hua)(hua)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；丹(dan)參(can)所(suo)(suo)含(han)(han)丹(dan)參(can)酮、原(yuan)(yuan)(yuan)兒茶醛(quan)、丹(dan)參(can)素(su)(su)(su)(su)等均有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)聚(ju)集(ji)(ji)、抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)形成(cheng)(cheng)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。川(chuan)芎(xiong)(xiong)(xiong)所(suo)(suo)含(han)(han)川(chuan)芎(xiong)(xiong)(xiong)嗪(qin)具(ju)(ju)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)激(ji)活(huo)腺苷(gan)環化(hua)(hua)(hua)(hua)酶(mei)(mei)(mei)的(de)(de)(de)(de)(de)(de)(de)(de)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，從(cong)(cong)而(er)使心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)內(nei)cAMP增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)，抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)Ca2+內(nei)流(liu)(liu)(liu)，同(tong)(tong)(tong)時(shi)(shi)(shi)(shi)(shi)川(chuan)芎(xiong)(xiong)(xiong)嗪(qin)還(huan)(huan)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)α1受體(ti)(ti)(ti)阻(zu)(zu)(zu)滯(zhi)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，可(ke)(ke)阻(zu)(zu)(zu)斷缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)早期(qi)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)臟細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)膜(mo)上(shang)(shang)成(cheng)(cheng)倍增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)的(de)(de)(de)(de)(de)(de)(de)(de)α1腎上(shang)(shang)腺受體(ti)(ti)(ti)，進而(er)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)由(you)于α1受體(ti)(ti)(ti)增(zeng)(zeng)(zeng)(zeng)多(duo)引起(qi)的(de)(de)(de)(de)(de)(de)(de)(de)大量(liang)(liang)(liang)(liang)Ca2+內(nei)流(liu)(liu)(liu)，從(cong)(cong)而(er)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)力地減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)Ca2+超載，降(jiang)(jiang)低(di)(di)(di)(di)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)FOS蛋白表達和減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)的(de)(de)(de)(de)(de)(de)(de)(de)凋(diao)亡。川(chuan)芎(xiong)(xiong)(xiong)嗪(qin)還(huan)(huan)可(ke)(ke)增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)收縮(suo)(suo)(suo)(suo)(suo)力、心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)率，增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)排血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)量(liang)(liang)(liang)(liang)，顯(xian)著(zhu)增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)冠(guan)脈(mo)(mo)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)流(liu)(liu)(liu)量(liang)(liang)(liang)(liang)，增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)機(ji)體(ti)(ti)(ti)內(nei)源(yuan)性(xing)(xing)(xing)(xing)SOD活(huo)性(xing)(xing)(xing)(xing)，降(jiang)(jiang)低(di)(di)(di)(di)MDA含(han)(han)量(liang)(liang)(liang)(liang)及(ji)(ji)水平(ping)(ping)，對(dui)(dui)休克再灌(guan)注(zhu)(zhu)損(sun)(sun)傷有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)防(fang)(fang)治作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，對(dui)(dui)異丙腎上(shang)(shang)腺素(su)(su)(su)(su)所(suo)(suo)致(zhi)(zhi)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)核鈣轉運功能(neng)(neng)(neng)(neng)(neng)下降(jiang)(jiang)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)拮(jie)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；川(chuan)芎(xiong)(xiong)(xiong)嗪(qin)對(dui)(dui)正常(chang)高(gao)(gao)(gao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)患者血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)平(ping)(ping)滑肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)Ca2+內(nei)流(liu)(liu)(liu)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，具(ju)(ju)擴(kuo)(kuo)(kuo)(kuo)張血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)和顯(xian)著(zhu)而(er)持久的(de)(de)(de)(de)(de)(de)(de)(de)降(jiang)(jiang)壓(ya)(ya)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，能(neng)(neng)(neng)(neng)(neng)降(jiang)(jiang)低(di)(di)(di)(di)肺動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)高(gao)(gao)(gao)壓(ya)(ya)，擴(kuo)(kuo)(kuo)(kuo)張腦血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)、冠(guan)狀(zhuang)(zhuang)動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)、腸系(xi)膜(mo)動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)、肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)，因(yin)此可(ke)(ke)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)效(xiao)地減(jian)(jian)(jian)(jian)輕(qing)(qing)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)臟后負荷；川(chuan)芎(xiong)(xiong)(xiong)嗪(qin)能(neng)(neng)(neng)(neng)(neng)改(gai)善微(wei)循環，對(dui)(dui)ADP、膠(jiao)原(yuan)(yuan)(yuan)、凝(ning)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)酶(mei)(mei)(mei)誘導血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)聚(ju)集(ji)(ji)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)顯(xian)著(zhu)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，還(huan)(huan)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)尿(niao)激(ji)酶(mei)(mei)(mei)樣作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，可(ke)(ke)直接激(ji)活(huo)纖(xian)溶(rong)酶(mei)(mei)(mei)原(yuan)(yuan)(yuan)，因(yin)此具(ju)(ju)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)很強(qiang)的(de)(de)(de)(de)(de)(de)(de)(de)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，而(er)且(qie)可(ke)(ke)使已形成(cheng)(cheng)的(de)(de)(de)(de)(de)(de)(de)(de)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)解(jie)聚(ju)和溶(rong)解(jie)。紅(hong)(hong)(hong)花(hua)水提(ti)(ti)(ti)(ti)取液及(ji)(ji)紅(hong)(hong)(hong)花(hua)黃(huang)(huang)素(su)(su)(su)(su)能(neng)(neng)(neng)(neng)(neng)提(ti)(ti)(ti)(ti)高(gao)(gao)(gao)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)再灌(guan)注(zhu)(zhu)時(shi)(shi)(shi)(shi)(shi)的(de)(de)(de)(de)(de)(de)(de)(de)LDH活(huo)性(xing)(xing)(xing)(xing)，減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)LPO的(de)(de)(de)(de)(de)(de)(de)(de)生(sheng)(sheng)成(cheng)(cheng)，提(ti)(ti)(ti)(ti)高(gao)(gao)(gao)SOD及(ji)(ji)GSHPx活(huo)性(xing)(xing)(xing)(xing)，清除自由(you)基(ji)(ji)，抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)氧(yang)化(hua)(hua)(hua)(hua)損(sun)(sun)傷，減(jian)(jian)(jian)(jian)輕(qing)(qing)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)超微(wei)結構損(sun)(sun)傷，因(yin)而(er)對(dui)(dui)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)、心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)梗(geng)死有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)明(ming)顯(xian)的(de)(de)(de)(de)(de)(de)(de)(de)保護作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，對(dui)(dui)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)律失常(chang)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)對(dui)(dui)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，使急性(xing)(xing)(xing)(xing)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)范(fan)圍縮(suo)(suo)(suo)(suo)(suo)小(xiao)(xiao)，程度減(jian)(jian)(jian)(jian)輕(qing)(qing)，心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)率減(jian)(jian)(jian)(jian)慢。紅(hong)(hong)(hong)花(hua)及(ji)(ji)其(qi)所(suo)(suo)含(han)(han)紅(hong)(hong)(hong)花(hua)素(su)(su)(su)(su)可(ke)(ke)直接阻(zu)(zu)(zu)斷α腎上(shang)(shang)腺素(su)(su)(su)(su)受體(ti)(ti)(ti)，因(yin)而(er)可(ke)(ke)擴(kuo)(kuo)(kuo)(kuo)張血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)、降(jiang)(jiang)低(di)(di)(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)、降(jiang)(jiang)低(di)(di)(di)(di)冠(guan)脈(mo)(mo)阻(zu)(zu)(zu)力、增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)冠(guan)脈(mo)(mo)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)流(liu)(liu)(liu)量(liang)(liang)(liang)(liang)和心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)營(ying)養性(xing)(xing)(xing)(xing)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)流(liu)(liu)(liu)量(liang)(liang)(liang)(liang)；同(tong)(tong)(tong)時(shi)(shi)(shi)(shi)(shi)紅(hong)(hong)(hong)花(hua)黃(huang)(huang)素(su)(su)(su)(su)可(ke)(ke)改(gai)善外(wai)周(zhou)循環障(zhang)礙，使血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)流(liu)(liu)(liu)加(jia)(jia)速(su)，毛細(xi)(xi)(xi)(xi)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)開放數目增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)，血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)聚(ju)集(ji)(ji)減(jian)(jian)(jian)(jian)輕(qing)(qing)；紅(hong)(hong)(hong)花(hua)黃(huang)(huang)素(su)(su)(su)(su)可(ke)(ke)延(yan)長血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)漿復鈣時(shi)(shi)(shi)(shi)(shi)間、凝(ning)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)酶(mei)(mei)(mei)原(yuan)(yuan)(yuan)時(shi)(shi)(shi)(shi)(shi)間及(ji)(ji)凝(ning)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)酶(mei)(mei)(mei)時(shi)(shi)(shi)(shi)(shi)間；紅(hong)(hong)(hong)花(hua)煎(jian)劑及(ji)(ji)紅(hong)(hong)(hong)花(hua)黃(huang)(huang)素(su)(su)(su)(su)能(neng)(neng)(neng)(neng)(neng)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)聚(ju)集(ji)(ji)，增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)纖(xian)維蛋白溶(rong)解(jie)，明(ming)顯(xian)降(jiang)(jiang)低(di)(di)(di)(di)纖(xian)維蛋白血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)的(de)(de)(de)(de)(de)(de)(de)(de)長度和重(zhong)量(liang)(liang)(liang)(liang)，防(fang)(fang)止(zhi)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)形成(cheng)(cheng)和發展。當(dang)歸(gui)及(ji)(ji)所(suo)(suo)含(han)(han)阿(a)魏(wei)酸(suan)可(ke)(ke)減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)內(nei)Ca2+、Na+蓄(xu)積(ji)(ji)，減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)MDA含(han)(han)量(liang)(liang)(liang)(liang)及(ji)(ji)生(sheng)(sheng)成(cheng)(cheng)，減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)CPK及(ji)(ji)LDH、AST釋放；降(jiang)(jiang)低(di)(di)(di)(di)冠(guan)狀(zhuang)(zhuang)脈(mo)(mo)阻(zu)(zu)(zu)力和心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)含(han)(han)水量(liang)(liang)(liang)(liang)，使心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)超微(wei)結構及(ji)(ji)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)功能(neng)(neng)(neng)(neng)(neng)明(ming)顯(xian)改(gai)善，因(yin)此可(ke)(ke)對(dui)(dui)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)再灌(guan)注(zhu)(zhu)損(sun)(sun)傷以及(ji)(ji)減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)梗(geng)死體(ti)(ti)(ti)積(ji)(ji)，保護心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)；阿(a)魏(wei)酸(suan)可(ke)(ke)減(jian)(jian)(jian)(jian)慢心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)傳導，延(yan)長有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)效(xiao)不應(ying)期(qi)，消除折返，延(yan)長平(ping)(ping)臺(tai)期(qi)，抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)異位節律點，提(ti)(ti)(ti)(ti)高(gao)(gao)(gao)致(zhi)(zhi)顫閾，對(dui)(dui)氯仿、腎上(shang)(shang)腺素(su)(su)(su)(su)、烏(wu)頭(tou)堿、毒毛花(hua)苷(gan)G誘發的(de)(de)(de)(de)(de)(de)(de)(de)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)律失常(chang)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)明(ming)顯(xian)的(de)(de)(de)(de)(de)(de)(de)(de)對(dui)(dui)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；當(dang)歸(gui)可(ke)(ke)擴(kuo)(kuo)(kuo)(kuo)張血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)、降(jiang)(jiang)低(di)(di)(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)，對(dui)(dui)腦血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)、冠(guan)狀(zhuang)(zhuang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)、肺血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)及(ji)(ji)周(zhou)圍血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)均有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)擴(kuo)(kuo)(kuo)(kuo)張作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；不僅(jin)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)促(cu)進造血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，而(er)且(qie)其(qi)水煎(jian)劑可(ke)(ke)延(yan)長血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)漿凝(ning)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)時(shi)(shi)(shi)(shi)(shi)間、凝(ning)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)活(huo)酶(mei)(mei)(mei)時(shi)(shi)(shi)(shi)(shi)間，降(jiang)(jiang)低(di)(di)(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)黏度，降(jiang)(jiang)低(di)(di)(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)漿纖(xian)維蛋白原(yuan)(yuan)(yuan)含(han)(han)量(liang)(liang)(liang)(liang)，延(yan)長凝(ning)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)酶(mei)(mei)(mei)原(yuan)(yuan)(yuan)時(shi)(shi)(shi)(shi)(shi)間，縮(suo)(suo)(suo)(suo)(suo)短RBC及(ji)(ji)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)電泳時(shi)(shi)(shi)(shi)(shi)間；阿(a)魏(wei)酸(suan)能(neng)(neng)(neng)(neng)(neng)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)膠(jiao)原(yuan)(yuan)(yuan)、ATP誘發的(de)(de)(de)(de)(de)(de)(de)(de)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)聚(ju)集(ji)(ji)，升高(gao)(gao)(gao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)內(nei)cAMP/cGMP比值，調整血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)PGI2/TXA2比值，使之(zhi)恢復平(ping)(ping)衡，因(yin)此具(ju)(ju)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)聚(ju)集(ji)(ji)和抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)形成(cheng)(cheng)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。臣藥?蟲所(suo)(suo)含(han)(han)總生(sheng)(sheng)物堿可(ke)(ke)升高(gao)(gao)(gao)右心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)房壓(ya)(ya)而(er)降(jiang)(jiang)低(di)(di)(di)(di)左(zuo)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)室收縮(suo)(suo)(suo)(suo)(suo)壓(ya)(ya)，而(er)且(qie)隨劑量(liang)(liang)(liang)(liang)增(zeng)(zeng)(zeng)(zeng)大而(er)增(zeng)(zeng)(zeng)(zeng)強(qiang)；同(tong)(tong)(tong)時(shi)(shi)(shi)(shi)(shi)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)直接擴(kuo)(kuo)(kuo)(kuo)張血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；?蟲水提(ti)(ti)(ti)(ti)物可(ke)(ke)明(ming)顯(xian)抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)聚(ju)集(ji)(ji)，顯(xian)著(zhu)增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)纖(xian)維溶(rong)酶(mei)(mei)(mei)活(huo)性(xing)(xing)(xing)(xing)，降(jiang)(jiang)低(di)(di)(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)干、濕重(zhong)量(liang)(liang)(liang)(liang)，減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)長度，具(ju)(ju)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)硬化(hua)(hua)(hua)(hua)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。生(sheng)(sheng)地同(tong)(tong)(tong)樣有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)促(cu)進造血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，而(er)且(qie)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)降(jiang)(jiang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)竭能(neng)(neng)(neng)(neng)(neng)增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)溶(rong)解(jie)酶(mei)(mei)(mei)的(de)(de)(de)(de)(de)(de)(de)(de)活(huo)性(xing)(xing)(xing)(xing)，促(cu)進纖(xian)溶(rong)活(huo)性(xing)(xing)(xing)(xing)，降(jiang)(jiang)低(di)(di)(di)(di)全血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)黏度和血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)漿黏度，增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)RBC及(ji)(ji)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)的(de)(de)(de)(de)(de)(de)(de)(de)穩定性(xing)(xing)(xing)(xing)，抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)(xiao)板(ban)聚(ju)集(ji)(ji)，具(ju)(ju)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)明(ming)顯(xian)的(de)(de)(de)(de)(de)(de)(de)(de)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)(shuan)及(ji)(ji)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)硬化(hua)(hua)(hua)(hua)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。佐藥白術有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)凝(ning)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，而(er)且(qie)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)明(ming)顯(xian)促(cu)進紅(hong)(hong)(hong)系(xi)造血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)生(sheng)(sheng)成(cheng)(cheng)的(de)(de)(de)(de)(de)(de)(de)(de)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，還(huan)(huan)能(neng)(neng)(neng)(neng)(neng)對(dui)(dui)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)免(mian)疫抑(yi)(yi)(yi)制(zhi)(zhi)(zhi)(zhi)劑所(suo)(suo)致(zhi)(zhi)WBC減(jian)(jian)(jian)(jian)少(shao)(shao)(shao)；同(tong)(tong)(tong)時(shi)(shi)(shi)(shi)(shi)白術能(neng)(neng)(neng)(neng)(neng)擴(kuo)(kuo)(kuo)(kuo)張血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)，降(jiang)(jiang)低(di)(di)(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)，但對(dui)(dui)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)房肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)呈負性(xing)(xing)(xing)(xing)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)力作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。陳皮(pi)水提(ti)(ti)(ti)(ti)物靜(jing)脈(mo)(mo)注(zhu)(zhu)射可(ke)(ke)顯(xian)著(zhu)增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)收縮(suo)(suo)(suo)(suo)(suo)幅(fu)度及(ji)(ji)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)輸(shu)出量(liang)(liang)(liang)(liang)，增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)脈(mo)(mo)壓(ya)(ya)差和每搏心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)排血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)量(liang)(liang)(liang)(liang)，提(ti)(ti)(ti)(ti)高(gao)(gao)(gao)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)臟指數，提(ti)(ti)(ti)(ti)高(gao)(gao)(gao)左(zuo)室作功指數。陳皮(pi)注(zhu)(zhu)射液及(ji)(ji)陳皮(pi)素(su)(su)(su)(su)靜(jing)脈(mo)(mo)注(zhu)(zhu)射有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)升高(gao)(gao)(gao)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)的(de)(de)(de)(de)(de)(de)(de)(de)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，甲(jia)基(ji)(ji)橙皮(pi)苷(gan)則有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)緩慢降(jiang)(jiang)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。山(shan)楂中的(de)(de)(de)(de)(de)(de)(de)(de)黃(huang)(huang)酮類化(hua)(hua)(hua)(hua)合(he)物具(ju)(ju)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)正性(xing)(xing)(xing)(xing)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)力作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，同(tong)(tong)(tong)時(shi)(shi)(shi)(shi)(shi)能(neng)(neng)(neng)(neng)(neng)延(yan)長動(dong)(dong)(dong)(dong)(dong)作電位時(shi)(shi)(shi)(shi)(shi)程和有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)效(xiao)不應(ying)期(qi)，具(ju)(ju)有(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)(you)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)律失常(chang)作用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；山(shan)楂增(zeng)(zeng)(zeng)(zeng)加(jia)(jia)冠(guan)狀(zhuang)(zhuang)脈(mo)(mo)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)流(liu)(liu)(liu)量(liang)(liang)(liang)(liang)的(de)(de)(de)(de)(de)(de)(de)(de)同(tong)(tong)(tong)時(shi)(shi)(shi)(shi)(shi)還(huan)(huan)能(neng)(neng)(neng)(neng)(neng)降(jiang)(jiang)低(di)(di)(di)(di)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)耗(hao)(hao)氧(yang)量(liang)(liang)(liang)(liang)，提(ti)(ti)(ti)(ti)高(gao)(gao)(gao)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)氧(yang)利用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)率，對(dui)(dui)抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)垂體(ti)(ti)(ti)后葉素(su)(su)(su)(su)及(ji)(ji)異丙腎上(shang)(shang)腺素(su)(su)(su)(su)所(suo)(suo)致(zhi)(zhi)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)缺(que)(que)(que)(que)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)，縮(suo)(suo)(suo)(suo)(suo)小(xiao)(xiao)心(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)(xin)肌(ji)(ji)(ji)(ji)(ji)(ji)(ji)梗(geng)死范(fan)圍；還(huan)(huan)能(neng)(neng)(neng)(neng)(neng)擴(kuo)(kuo)(kuo)(kuo)張外(wai)圍血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)，降(jiang)(jiang)低(di)(di)(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)和抗(kang)(kang)(kang)(kang)(kang)(kang)(kang)(kang)動(dong)(dong)(dong)(dong)(dong)脈(mo)(mo)硬化(hua)(hua)(hua)(hua)。
由(you)此(ci)可(ke)見該方劑有(you)10味藥對心(xin)血(xue)(xue)(xue)管(guan)功能(neng)具有(you)一(yi)致性(xing)的積極作用(yong)，增加心(xin)肌(ji)收縮力，增加冠脈血(xue)(xue)(xue)流，抗心(xin)肌(ji)缺血(xue)(xue)(xue)，抗心(xin)律失常，擴張血(xue)(xue)(xue)管(guan)，降低血(xue)(xue)(xue)壓，改善微循環，改變(bian)血(xue)(xue)(xue)液(ye)流變(bian)性(xing)，抗血(xue)(xue)(xue)栓(shuan)形成及溶解血(xue)(xue)(xue)栓(shuan)。這些作用(yong)對于重癥感染(ran)特(te)別是(shi)感染(ran)性(xing)休克(ke)、中毒型痢疾、暴發型流腦(nao)等(deng)所致心(xin)血(xue)(xue)(xue)管(guan)功能(neng)障(zhang)礙(ai)的治(zhi)療十分重要。
3.7.4對(dui)(dui)(dui)(dui)消化(hua)(hua)系統(tong)功能(neng)(neng)(neng)的(de)(de)(de)影(ying)響 君藥丹參可(ke)減(jian)(jian)少TNFα的(de)(de)(de)合成(cheng)，減(jian)(jian)少缺血(xue)再灌注引起的(de)(de)(de)肝(gan)(gan)(gan)(gan)(gan)臟不(bu)可(ke)逆損(sun)(sun)傷(shang)，同(tong)(tong)時可(ke)促進肝(gan)(gan)(gan)(gan)(gan)血(xue)液(ye)循(xun)環，促進肝(gan)(gan)(gan)(gan)(gan)細(xi)胞(bao)(bao)(bao)RNA、DNA的(de)(de)(de)合成(cheng)，增(zeng)(zeng)加核分(fen)裂相(xiang)(xiang)指數，從(cong)(cong)而(er)促進肝(gan)(gan)(gan)(gan)(gan)細(xi)胞(bao)(bao)(bao)再生(sheng)(sheng)；丹參不(bu)僅能(neng)(neng)(neng)抑(yi)(yi)制(zhi)(zhi)肝(gan)(gan)(gan)(gan)(gan)纖(xian)維組(zu)織(zhi)增(zeng)(zeng)生(sheng)(sheng)，還能(neng)(neng)(neng)使(shi)已增(zeng)(zeng)生(sheng)(sheng)的(de)(de)(de)肝(gan)(gan)(gan)(gan)(gan)纖(xian)維組(zu)織(zhi)消散和吸收，因此具(ju)有(you)(you)(you)明顯(xian)抗(kang)肝(gan)(gan)(gan)(gan)(gan)硬化(hua)(hua)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；丹參所(suo)含(han)丹酚(fen)酸(suan)(suan)(suan)(suan)A可(ke)抑(yi)(yi)制(zhi)(zhi)胃(wei)(wei)(wei)H+K+ATP酶(mei)，從(cong)(cong)而(er)抑(yi)(yi)制(zhi)(zhi)胃(wei)(wei)(wei)酸(suan)(suan)(suan)(suan)分(fen)泌(mi)，具(ju)有(you)(you)(you)抗(kang)胃(wei)(wei)(wei)潰(kui)瘍(yang)及(ji)促進潰(kui)瘍(yang)愈合的(de)(de)(de)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。川芎(xiong)嗪(qin)能(neng)(neng)(neng)抑(yi)(yi)制(zhi)(zhi)重(zhong)癥急性胰(yi)(yi)腺炎內皮素(su)生(sheng)(sheng)成(cheng)，促進前列腺環素(su)生(sheng)(sheng)成(cheng)，穩定二者(zhe)平(ping)(ping)衡，從(cong)(cong)而(er)改善重(zhong)癥胰(yi)(yi)腺炎并發(fa)(fa)肺(fei)損(sun)(sun)傷(shang)；川芎(xiong)浸膏微量(liang)(liang)(liang)即能(neng)(neng)(neng)減(jian)(jian)慢小(xiao)腸(chang)(chang)(chang)收縮(suo)，大(da)量(liang)(liang)(liang)可(ke)使(shi)收縮(suo)完(wan)全(quan)停(ting)止，其(qi)所(suo)含(han)阿(a)(a)魏酸(suan)(suan)(suan)(suan)也有(you)(you)(you)解痙(jing)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。紅花煎劑(ji)對(dui)(dui)(dui)(dui)腸(chang)(chang)(chang)道(dao)平(ping)(ping)滑肌作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)不(bu)一致，主要(yao)是興奮(fen)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，但也表現為抑(yi)(yi)制(zhi)(zhi)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，對(dui)(dui)(dui)(dui)乙(yi)酰膽(dan)堿所(suo)致腸(chang)(chang)(chang)管痙(jing)攣有(you)(you)(you)解痙(jing)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。當歸(gui)(gui)能(neng)(neng)(neng)增(zeng)(zeng)加肝(gan)(gan)(gan)(gan)(gan)GSHPx活性，降(jiang)(jiang)(jiang)低(di)(di)肝(gan)(gan)(gan)(gan)(gan)細(xi)胞(bao)(bao)(bao)漿中MDA含(han)量(liang)(liang)(liang)，具(ju)有(you)(you)(you)抗(kang)脂(zhi)(zhi)質過氧化(hua)(hua)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，因而(er)有(you)(you)(you)保(bao)肝(gan)(gan)(gan)(gan)(gan)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，同(tong)(tong)時可(ke)顯(xian)著(zhu)降(jiang)(jiang)(jiang)低(di)(di)肝(gan)(gan)(gan)(gan)(gan)臟膠原蛋(dan)白(bai)含(han)量(liang)(liang)(liang)，減(jian)(jian)輕肝(gan)(gan)(gan)(gan)(gan)纖(xian)維化(hua)(hua)，當歸(gui)(gui)水(shui)(shui)提(ti)物(wu)(wu)、揮(hui)(hui)發(fa)(fa)油或(huo)阿(a)(a)魏酸(suan)(suan)(suan)(suan)均能(neng)(neng)(neng)促進膽(dan)汁分(fen)泌(mi)，并增(zeng)(zeng)加膽(dan)汁中固(gu)體物(wu)(wu)及(ji)膽(dan)酸(suan)(suan)(suan)(suan)的(de)(de)(de)排泄(xie)量(liang)(liang)(liang)，阿(a)(a)魏酸(suan)(suan)(suan)(suan)還能(neng)(neng)(neng)抑(yi)(yi)制(zhi)(zhi)胃(wei)(wei)(wei)腸(chang)(chang)(chang)推進運動，當歸(gui)(gui)揮(hui)(hui)發(fa)(fa)油能(neng)(neng)(neng)抑(yi)(yi)制(zhi)(zhi)乙(yi)酰膽(dan)堿所(suo)致腸(chang)(chang)(chang)收縮(suo)。臣藥?蟲己烷(wan)可(ke)溶(rong)部分(fen)可(ke)明顯(xian)減(jian)(jian)輕D半乳糖胺所(suo)致肝(gan)(gan)(gan)(gan)(gan)損(sun)(sun)傷(shang)程度(du)。生(sheng)(sheng)地能(neng)(neng)(neng)抑(yi)(yi)制(zhi)(zhi)胃(wei)(wei)(wei)液(ye)及(ji)總酸(suan)(suan)(suan)(suan)排出(chu)量(liang)(liang)(liang)，具(ju)有(you)(you)(you)抗(kang)潰(kui)瘍(yang)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。佐藥白(bai)術(shu)水(shui)(shui)煎劑(ji)可(ke)減(jian)(jian)輕肝(gan)(gan)(gan)(gan)(gan)細(xi)胞(bao)(bao)(bao)變(bian)性和壞死，促進肝(gan)(gan)(gan)(gan)(gan)細(xi)胞(bao)(bao)(bao)生(sheng)(sheng)長，降(jiang)(jiang)(jiang)低(di)(di)ALT，減(jian)(jian)輕肝(gan)(gan)(gan)(gan)(gan)糖元(yuan)減(jian)(jian)少，顯(xian)著(zhu)防治(zhi)四氯化(hua)(hua)碳所(suo)致的(de)(de)(de)肝(gan)(gan)(gan)(gan)(gan)損(sun)(sun)傷(shang)。白(bai)術(shu)丙酮提(ti)取物(wu)(wu)可(ke)抑(yi)(yi)制(zhi)(zhi)胃(wei)(wei)(wei)液(ye)分(fen)泌(mi)，降(jiang)(jiang)(jiang)低(di)(di)胃(wei)(wei)(wei)液(ye)酸(suan)(suan)(suan)(suan)度(du)，減(jian)(jian)少胃(wei)(wei)(wei)酸(suan)(suan)(suan)(suan)排出(chu)量(liang)(liang)(liang)；還能(neng)(neng)(neng)促進胃(wei)(wei)(wei)黏膜細(xi)胞(bao)(bao)(bao)增(zeng)(zeng)殖， *** 胃(wei)(wei)(wei)蛋(dan)白(bai)酶(mei)分(fen)泌(mi)，對(dui)(dui)(dui)(dui)胃(wei)(wei)(wei)潰(kui)瘍(yang)及(ji)各種慢性胃(wei)(wei)(wei)病有(you)(you)(you)防治(zhi)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；白(bai)術(shu)對(dui)(dui)(dui)(dui)胃(wei)(wei)(wei)腸(chang)(chang)(chang)運動呈雙(shuang)相(xiang)(xiang)調(diao)節作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，當腸(chang)(chang)(chang)管受(shou)乙(yi)酰膽(dan)堿作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)而(er)處于(yu)興奮(fen)狀態時，白(bai)術(shu)抑(yi)(yi)制(zhi)(zhi)之(zhi)，當腸(chang)(chang)(chang)管受(shou)腎(shen)上腺素(su)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)而(er)處于(yu)抑(yi)(yi)制(zhi)(zhi)狀態時，白(bai)術(shu)則興奮(fen)之(zhi)，從(cong)(cong)而(er)使(shi)胃(wei)(wei)(wei)腸(chang)(chang)(chang)運動恢復(fu)正常；白(bai)術(shu)水(shui)(shui)煎劑(ji)對(dui)(dui)(dui)(dui)胃(wei)(wei)(wei)腸(chang)(chang)(chang)運動有(you)(you)(you)興奮(fen)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，而(er)其(qi)揮(hui)(hui)發(fa)(fa)油則有(you)(you)(you)抑(yi)(yi)制(zhi)(zhi)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。山楂(zha)及(ji)山楂(zha)黃(huang)酮可(ke)顯(xian)著(zhu)降(jiang)(jiang)(jiang)低(di)(di)血(xue)清及(ji)肝(gan)(gan)(gan)(gan)(gan)臟MDA含(han)量(liang)(liang)(liang)，增(zeng)(zeng)強肝(gan)(gan)(gan)(gan)(gan)臟SOD活性及(ji)GSHPx活性，具(ju)有(you)(you)(you)保(bao)肝(gan)(gan)(gan)(gan)(gan)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)；山楂(zha)含(han)有(you)(you)(you)脂(zhi)(zhi)肪(fang)酶(mei)，能(neng)(neng)(neng)促進脂(zhi)(zhi)肪(fang)的(de)(de)(de)消化(hua)(hua)，增(zeng)(zeng)加胃(wei)(wei)(wei)消化(hua)(hua)酶(mei)的(de)(de)(de)分(fen)泌(mi)，促進消化(hua)(hua)和吸收；同(tong)(tong)時對(dui)(dui)(dui)(dui)胃(wei)(wei)(wei)腸(chang)(chang)(chang)平(ping)(ping)滑肌亦呈雙(shuang)相(xiang)(xiang)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，對(dui)(dui)(dui)(dui)活動亢(kang)進的(de)(de)(de)平(ping)(ping)滑肌有(you)(you)(you)抑(yi)(yi)制(zhi)(zhi)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)，對(dui)(dui)(dui)(dui)松弛的(de)(de)(de)胃(wei)(wei)(wei)腸(chang)(chang)(chang)平(ping)(ping)滑肌有(you)(you)(you)輕度(du)的(de)(de)(de)增(zeng)(zeng)強其(qi)收縮(suo)的(de)(de)(de)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。麥芽可(ke)抑(yi)(yi)制(zhi)(zhi)高脂(zhi)(zhi)飲(yin)食誘(you)導的(de)(de)(de)肝(gan)(gan)(gan)(gan)(gan)組(zu)織(zhi)膽(dan)固(gu)醇、三酰甘油、過氧化(hua)(hua)脂(zhi)(zhi)質含(han)量(liang)(liang)(liang)的(de)(de)(de)增(zeng)(zeng)加。神曲含(han)大(da)量(liang)(liang)(liang)酵母菌、酶(mei)類(lei)、維生(sheng)(sheng)素(su)B復(fu)合體等，有(you)(you)(you)促進消化(hua)(hua)、增(zeng)(zeng)進食欲(yu)的(de)(de)(de)作(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)(yong)(yong)。
從以(yi)上可以(yi)看出該方劑所有藥(yao)味均對(dui)消(xiao)化(hua)系統功能有不同程度、不同范(fan)圍的積極促進作(zuo)用，保肝、利膽、抗潰瘍(yang)，促消(xiao)化(hua)，調節胃腸功能運動(dong)。
3.7.5對(dui)(dui)免(mian)(mian)疫(yi)系統功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)的(de)(de)(de)影(ying)(ying)響(xiang) 君藥(yao)丹(dan)參(can)對(dui)(dui)免(mian)(mian)疫(yi)系統的(de)(de)(de)影(ying)(ying)響(xiang)比較復雜，丹(dan)參(can)煎(jian)(jian)劑口(kou)服可(ke)(ke)(ke)明(ming)(ming)(ming)(ming)顯(xian)(xian)提(ti)(ti)高(gao)(gao)(gao)巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)的(de)(de)(de)吞噬(shi)(shi)(shi)(shi)百分(fen)(fen)(fen)率及(ji)(ji)(ji)(ji)吞噬(shi)(shi)(shi)(shi)指數，能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)提(ti)(ti)高(gao)(gao)(gao)脾(pi)臟抗(kang)(kang)體(ti)(ti)生(sheng)(sheng)(sheng)(sheng)成(cheng)(cheng)(cheng)數／脾(pi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)值，說明(ming)(ming)(ming)(ming)丹(dan)參(can)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)促(cu)進(jin)(jin)(jin)體(ti)(ti)液(ye)(ye)免(mian)(mian)疫(yi)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)；但丹(dan)參(can)注射(she)液(ye)(ye)則抑(yi)(yi)(yi)制(zhi)(zhi)吞噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)吞噬(shi)(shi)(shi)(shi)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)，降(jiang)低(di)T淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)轉(zhuan)化(hua)(hua)(hua)率，抑(yi)(yi)(yi)制(zhi)(zhi)遲(chi)發(fa)型超敏反(fan)(fan)應(ying)(ying)，對(dui)(dui)于同(tong)(tong)(tong)種異體(ti)(ti)移植(zhi)，丹(dan)參(can)注射(she)液(ye)(ye)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)減輕移植(zhi)的(de)(de)(de)毛(mao)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)血(xue)(xue)(xue)管損(sun)傷，減輕免(mian)(mian)疫(yi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)浸潤，還能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)直接(jie)對(dui)(dui)抗(kang)(kang)體(ti)(ti)液(ye)(ye)和(he)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)免(mian)(mian)疫(yi)的(de)(de)(de)排斥反(fan)(fan)應(ying)(ying)。川芎所含(han)(han)川芎嗪能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)增(zeng)(zeng)(zeng)強單(dan)核巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)的(de)(de)(de)吞噬(shi)(shi)(shi)(shi)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)，提(ti)(ti)高(gao)(gao)(gao)淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)轉(zhuan)化(hua)(hua)(hua)率，提(ti)(ti)高(gao)(gao)(gao)ANAE陽(yang)(yang)性(xing)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)的(de)(de)(de)百分(fen)(fen)(fen)率，促(cu)進(jin)(jin)(jin)SRBC抗(kang)(kang)體(ti)(ti)的(de)(de)(de)形(xing)成(cheng)(cheng)(cheng)。紅花(hua)(hua)(hua)具有免(mian)(mian)疫(yi)調節作(zuo)(zuo)用(yong)，紅花(hua)(hua)(hua)黃素(su)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)降(jiang)低(di)血(xue)(xue)(xue)清溶菌(jun)酶含(han)(han)量(liang)，降(jiang)低(di)巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)及(ji)(ji)(ji)(ji)WBC吞噬(shi)(shi)(shi)(shi)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)，使空斑(ban)形(xing)成(cheng)(cheng)(cheng)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)數、脾(pi)特(te)異性(xing)玫(mei)瑰花(hua)(hua)(hua)環形(xing)成(cheng)(cheng)(cheng)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)和(he)抗(kang)(kang)體(ti)(ti)產(chan)生(sheng)(sheng)(sheng)(sheng)減少(shao)，抑(yi)(yi)(yi)制(zhi)(zhi)遲(chi)發(fa)型超敏反(fan)(fan)應(ying)(ying)；抑(yi)(yi)(yi)制(zhi)(zhi)TS細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)活(huo)(huo)化(hua)(hua)(hua)，抑(yi)(yi)(yi)制(zhi)(zhi)T、B淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)轉(zhuan)化(hua)(hua)(hua)及(ji)(ji)(ji)(ji)IL2的(de)(de)(de)產(chan)生(sheng)(sheng)(sheng)(sheng)和(he)活(huo)(huo)化(hua)(hua)(hua)；紅花(hua)(hua)(hua)注射(she)液(ye)(ye)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)使ANAE檢(jian)測陽(yang)(yang)性(xing)百分(fen)(fen)(fen)率提(ti)(ti)高(gao)(gao)(gao)。當(dang)歸(gui)(gui)(gui)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)增(zeng)(zeng)(zeng)強巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)吞噬(shi)(shi)(shi)(shi)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)，當(dang)歸(gui)(gui)(gui)醇(chun)沉(chen)物單(dan)獨(du)或協同(tong)(tong)(tong)ComA/LPS發(fa)揮(hui)促(cu)進(jin)(jin)(jin)脾(pi)臟及(ji)(ji)(ji)(ji)胸腺(xian)T、B淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)增(zeng)(zeng)(zeng)殖(zhi)(zhi)作(zuo)(zuo)用(yong)，拮(jie)抗(kang)(kang)氫(qing)化(hua)(hua)(hua)可(ke)(ke)(ke)的(de)(de)(de)松對(dui)(dui)其(qi)的(de)(de)(de)抑(yi)(yi)(yi)制(zhi)(zhi)作(zuo)(zuo)用(yong)；當(dang)歸(gui)(gui)(gui)內酶能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)增(zeng)(zeng)(zeng)強細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)毒T細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)，增(zeng)(zeng)(zeng)加(jia)(jia)(jia)其(qi)殺傷活(huo)(huo)性(xing)；當(dang)歸(gui)(gui)(gui)活(huo)(huo)性(xing)多糖可(ke)(ke)(ke)促(cu)進(jin)(jin)(jin)脾(pi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)增(zeng)(zeng)(zeng)殖(zhi)(zhi)，具有免(mian)(mian)疫(yi)佐劑樣作(zuo)(zuo)用(yong)，當(dang)歸(gui)(gui)(gui)注射(she)液(ye)(ye)可(ke)(ke)(ke)提(ti)(ti)高(gao)(gao)(gao)抗(kang)(kang)體(ti)(ti)數量(liang)及(ji)(ji)(ji)(ji)效(xiao)價。當(dang)歸(gui)(gui)(gui)醇(chun)沉(chen)物及(ji)(ji)(ji)(ji)其(qi)中性(xing)組分(fen)(fen)(fen)可(ke)(ke)(ke)顯(xian)(xian)著增(zeng)(zeng)(zeng)強巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)分(fen)(fen)(fen)泌(mi)TNFα、IL1;當(dang)歸(gui)(gui)(gui)所含(han)(han)阿(a)魏酸對(dui)(dui)脾(pi)淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)DNA合(he)成(cheng)(cheng)(cheng)有活(huo)(huo)化(hua)(hua)(hua)作(zuo)(zuo)用(yong)，在ConA *** 下作(zuo)(zuo)用(yong)更顯(xian)(xian)著；當(dang)歸(gui)(gui)(gui)注射(she)液(ye)(ye)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)顯(xian)(xian)著增(zeng)(zeng)(zeng)加(jia)(jia)(jia)IL2的(de)(de)(de)產(chan)生(sheng)(sheng)(sheng)(sheng)，能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)誘(you)生(sheng)(sheng)(sheng)(sheng)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)因子，誘(you)生(sheng)(sheng)(sheng)(sheng)脾(pi)淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)分(fen)(fen)(fen)泌(mi)IFNγ及(ji)(ji)(ji)(ji)增(zeng)(zeng)(zeng)加(jia)(jia)(jia)IFNγ活(huo)(huo)性(xing)。生(sheng)(sheng)(sheng)(sheng)地及(ji)(ji)(ji)(ji)其(qi)所含(han)(han)多糖明(ming)(ming)(ming)(ming)顯(xian)(xian)提(ti)(ti)高(gao)(gao)(gao)T淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)的(de)(de)(de)增(zeng)(zeng)(zeng)殖(zhi)(zhi)反(fan)(fan)應(ying)(ying)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)力(li)，促(cu)進(jin)(jin)(jin)IL2的(de)(de)(de)分(fen)(fen)(fen)泌(mi)；生(sheng)(sheng)(sheng)(sheng)地水(shui)(shui)煎(jian)(jian)劑促(cu)進(jin)(jin)(jin)ConA誘(you)導的(de)(de)(de)脾(pi)淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)DNA及(ji)(ji)(ji)(ji)蛋(dan)白(bai)(bai)(bai)質的(de)(de)(de)生(sheng)(sheng)(sheng)(sheng)物合(he)成(cheng)(cheng)(cheng)，增(zeng)(zeng)(zeng)強巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)，拮(jie)抗(kang)(kang)氫(qing)化(hua)(hua)(hua)可(ke)(ke)(ke)的(de)(de)(de)松引起(qi)的(de)(de)(de)血(xue)(xue)(xue)中淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)減少(shao)及(ji)(ji)(ji)(ji)對(dui)(dui)巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)的(de)(de)(de)抑(yi)(yi)(yi)制(zhi)(zhi)；生(sheng)(sheng)(sheng)(sheng)地還能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)誘(you)生(sheng)(sheng)(sheng)(sheng)人干擾素(su)，使之(zhi)效(xiao)價明(ming)(ming)(ming)(ming)顯(xian)(xian)提(ti)(ti)高(gao)(gao)(gao)。佐藥(yao)白(bai)(bai)(bai)術水(shui)(shui)浸劑能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)明(ming)(ming)(ming)(ming)顯(xian)(xian)增(zeng)(zeng)(zeng)加(jia)(jia)(jia)抗(kang)(kang)體(ti)(ti)產(chan)生(sheng)(sheng)(sheng)(sheng)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)力(li)，增(zeng)(zeng)(zeng)強淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)轉(zhuan)化(hua)(hua)(hua)率以及(ji)(ji)(ji)(ji)巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)吞噬(shi)(shi)(shi)(shi)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)，可(ke)(ke)(ke)促(cu)進(jin)(jin)(jin)骨髓(sui)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)增(zeng)(zeng)(zeng)殖(zhi)(zhi)反(fan)(fan)應(ying)(ying)和(he)IL1、IL2的(de)(de)(de)分(fen)(fen)(fen)泌(mi)，提(ti)(ti)高(gao)(gao)(gao)外周的(de)(de)(de)WBC數量(liang)，增(zeng)(zeng)(zeng)加(jia)(jia)(jia)脾(pi)和(he)胸腺(xian)的(de)(de)(de)重量(liang)，同(tong)(tong)(tong)時(shi)增(zeng)(zeng)(zeng)加(jia)(jia)(jia)T淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)；白(bai)(bai)(bai)術多糖可(ke)(ke)(ke)促(cu)進(jin)(jin)(jin)淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)轉(zhuan)化(hua)(hua)(hua)，提(ti)(ti)高(gao)(gao)(gao)IL2分(fen)(fen)(fen)泌(mi)水(shui)(shui)平，促(cu)進(jin)(jin)(jin)淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)增(zeng)(zeng)(zeng)殖(zhi)(zhi)；白(bai)(bai)(bai)術揮(hui)發(fa)油可(ke)(ke)(ke)增(zeng)(zeng)(zeng)強機體(ti)(ti)非(fei)特(te)異性(xing)免(mian)(mian)疫(yi)功(gong)(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)，提(ti)(ti)高(gao)(gao)(gao)巨(ju)噬(shi)(shi)(shi)(shi)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)活(huo)(huo)性(xing)。陳(chen)皮(pi)水(shui)(shui)煎(jian)(jian)醇(chun)沉(chen)液(ye)(ye)可(ke)(ke)(ke)顯(xian)(xian)著增(zeng)(zeng)(zeng)加(jia)(jia)(jia)血(xue)(xue)(xue)清溶菌(jun)酶含(han)(han)量(liang)，增(zeng)(zeng)(zeng)加(jia)(jia)(jia)血(xue)(xue)(xue)清血(xue)(xue)(xue)凝抗(kang)(kang)體(ti)(ti)滴度，增(zeng)(zeng)(zeng)加(jia)(jia)(jia)心臟T淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)E玫(mei)瑰花(hua)(hua)(hua)環形(xing)成(cheng)(cheng)(cheng)率，但對(dui)(dui)T淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)轉(zhuan)化(hua)(hua)(hua)率卻有明(ming)(ming)(ming)(ming)顯(xian)(xian)抑(yi)(yi)(yi)制(zhi)(zhi)作(zuo)(zuo)用(yong)。山(shan)楂水(shui)(shui)煎(jian)(jian)劑能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)明(ming)(ming)(ming)(ming)顯(xian)(xian)增(zeng)(zeng)(zeng)加(jia)(jia)(jia)脾(pi)臟、胸腺(xian)重量(liang)，增(zeng)(zeng)(zeng)加(jia)(jia)(jia)血(xue)(xue)(xue)清溶菌(jun)酶含(han)(han)量(liang)，提(ti)(ti)高(gao)(gao)(gao)血(xue)(xue)(xue)清抗(kang)(kang)體(ti)(ti)滴度，提(ti)(ti)高(gao)(gao)(gao)淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)轉(zhuan)化(hua)(hua)(hua)率及(ji)(ji)(ji)(ji)T淋(lin)(lin)巴(ba)(ba)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)ANAE陽(yang)(yang)性(xing)細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)百分(fen)(fen)(fen)率，因此對(dui)(dui)體(ti)(ti)液(ye)(ye)免(mian)(mian)疫(yi)、細(xi)(xi)(xi)(xi)(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)(bao)(bao)免(mian)(mian)疫(yi)及(ji)(ji)(ji)(ji)非(fei)特(te)異性(xing)免(mian)(mian)疫(yi)均有增(zeng)(zeng)(zeng)強作(zuo)(zuo)用(yong)。
由以(yi)上可以(yi)看(kan)出該(gai)方(fang)劑有(you)免疫增強、促進及免疫調節作用。
3.7.6抗(kang)炎及(ji)(ji)(ji)(ji)抗(kang)氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)損(sun)(sun)(sun)傷(shang)(shang)(shang)作(zuo)(zuo)用(yong)(yong) 君藥丹(dan)參及(ji)(ji)(ji)(ji)所含(han)丹(dan)參酮(tong)通過顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)抑(yi)制(zhi)(zhi)WBC化(hua)(hua)(hua)(hua)學運動，阻止WBC向炎癥處游(you)走(zou)及(ji)(ji)(ji)(ji)聚集，防止溶酶體酶氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)代謝產(chan)物等(deng)釋放，減輕組織損(sun)(sun)(sun)傷(shang)(shang)(shang)而(er)有(you)(you)明(ming)顯(xian)(xian)(xian)(xian)(xian)的(de)(de)(de)(de)(de)(de)抗(kang)炎作(zuo)(zuo)用(yong)(yong)；對(dui)(dui)炎癥的(de)(de)(de)(de)(de)(de)毛(mao)細(xi)血(xue)(xue)管(guan)(guan)通透性(xing)(xing)(xing)(xing)增(zeng)(zeng)加(jia)、滲出、水腫(zhong)等(deng)都有(you)(you)抑(yi)制(zhi)(zhi)作(zuo)(zuo)用(yong)(yong)；丹(dan)參能(neng)明(ming)顯(xian)(xian)(xian)(xian)(xian)提(ti)(ti)(ti)高RBC、心、肝(gan)、腎中(zhong)的(de)(de)(de)(de)(de)(de)SOD活(huo)(huo)性(xing)(xing)(xing)(xing)，顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)降(jiang)低(di)(di)LPO含(han)量(liang)，強(qiang)(qiang)有(you)(you)力(li)地清(qing)(qing)(qing)除(chu)超(chao)氧(yang)(yang)(yang)陰離(li)子(zi)自(zi)由(you)(you)(you)基(ji)(ji)(ji)及(ji)(ji)(ji)(ji)羥(qian)(qian)基(ji)(ji)(ji)，具(ju)(ju)有(you)(you)顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)的(de)(de)(de)(de)(de)(de)抗(kang)氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)損(sun)(sun)(sun)傷(shang)(shang)(shang)作(zuo)(zuo)用(yong)(yong)。川芎嗪能(neng)顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)抑(yi)制(zhi)(zhi)炎癥的(de)(de)(de)(de)(de)(de)纖維組織增(zeng)(zeng)生(sheng)，同時對(dui)(dui)水溶體系產(chan)生(sheng)的(de)(de)(de)(de)(de)(de)超(chao)氧(yang)(yang)(yang)陰離(li)子(zi)自(zi)由(you)(you)(you)基(ji)(ji)(ji)及(ji)(ji)(ji)(ji)羥(qian)(qian)基(ji)(ji)(ji)有(you)(you)明(ming)顯(xian)(xian)(xian)(xian)(xian)的(de)(de)(de)(de)(de)(de)清(qing)(qing)(qing)除(chu)作(zuo)(zuo)用(yong)(yong)，能(neng)直接捕獲自(zi)由(you)(you)(you)基(ji)(ji)(ji)，提(ti)(ti)(ti)高血(xue)(xue)中(zhong)SOD活(huo)(huo)性(xing)(xing)(xing)(xing)，具(ju)(ju)有(you)(you)顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)的(de)(de)(de)(de)(de)(de)抗(kang)氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)損(sun)(sun)(sun)傷(shang)(shang)(shang)作(zuo)(zuo)用(yong)(yong)。紅(hong)花所含(han)紅(hong)花黃(huang)色素以及(ji)(ji)(ji)(ji)棕(zong)櫚酸(suan)、肉豆蔻酸(suan)、月桂酸(suan)等(deng)成分對(dui)(dui)炎癥的(de)(de)(de)(de)(de)(de)毛(mao)細(xi)血(xue)(xue)管(guan)(guan)通透性(xing)(xing)(xing)(xing)增(zeng)(zeng)加(jia)、棉球肉芽腫(zhong)形成具(ju)(ju)有(you)(you)顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)抑(yi)制(zhi)(zhi)作(zuo)(zuo)用(yong)(yong)；紅(hong)花水提(ti)(ti)(ti)液可消(xiao)除(chu)羥(qian)(qian)基(ji)(ji)(ji)，抑(yi)制(zhi)(zhi)自(zi)由(you)(you)(you)基(ji)(ji)(ji)誘發(fa)的(de)(de)(de)(de)(de)(de)脂(zhi)(zhi)質(zhi)過氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)作(zuo)(zuo)用(yong)(yong)，且呈明(ming)顯(xian)(xian)(xian)(xian)(xian)的(de)(de)(de)(de)(de)(de)量(liang)效關系。當(dang)歸水煎(jian)劑對(dui)(dui)多種原因所致炎癥均(jun)有(you)(you)明(ming)顯(xian)(xian)(xian)(xian)(xian)的(de)(de)(de)(de)(de)(de)抑(yi)制(zhi)(zhi)作(zuo)(zuo)用(yong)(yong)，并(bing)(bing)能(neng)降(jiang)低(di)(di)炎癥組織中(zhong)的(de)(de)(de)(de)(de)(de)PGE2釋放量(liang)，降(jiang)低(di)(di)補體旁路(lu)溶血(xue)(xue)活(huo)(huo)性(xing)(xing)(xing)(xing)，同時可清(qing)(qing)(qing)除(chu)超(chao)氧(yang)(yang)(yang)陰離(li)子(zi)自(zi)由(you)(you)(you)基(ji)(ji)(ji)及(ji)(ji)(ji)(ji)羥(qian)(qian)基(ji)(ji)(ji)，當(dang)歸注射液能(neng)明(ming)顯(xian)(xian)(xian)(xian)(xian)增(zeng)(zeng)加(jia)血(xue)(xue)中(zhong)SOD活(huo)(huo)性(xing)(xing)(xing)(xing)，清(qing)(qing)(qing)除(chu)超(chao)氧(yang)(yang)(yang)陰離(li)子(zi)自(zi)由(you)(you)(you)基(ji)(ji)(ji)，對(dui)(dui)抗(kang)脂(zhi)(zhi)質(zhi)過氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)反應。臣藥生(sheng)地對(dui)(dui)實驗性(xing)(xing)(xing)(xing)關節炎有(you)(you)明(ming)顯(xian)(xian)(xian)(xian)(xian)的(de)(de)(de)(de)(de)(de)消(xiao)腫(zhong)作(zuo)(zuo)用(yong)(yong)，其(qi)水煎(jian)劑能(neng)明(ming)顯(xian)(xian)(xian)(xian)(xian)增(zeng)(zeng)加(jia)血(xue)(xue)清(qing)(qing)(qing)中(zhong)GSHPx活(huo)(huo)性(xing)(xing)(xing)(xing)，降(jiang)低(di)(di)LPO含(han)量(liang)，提(ti)(ti)(ti)高腦(nao)SOD活(huo)(huo)性(xing)(xing)(xing)(xing)，降(jiang)低(di)(di)腦(nao)MDA含(han)量(liang)，具(ju)(ju)有(you)(you)顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)的(de)(de)(de)(de)(de)(de)抗(kang)氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)損(sun)(sun)(sun)傷(shang)(shang)(shang)作(zuo)(zuo)用(yong)(yong)。血(xue)(xue)竭(jie)具(ju)(ju)有(you)(you)顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)的(de)(de)(de)(de)(de)(de)抗(kang)炎作(zuo)(zuo)用(yong)(yong)，并(bing)(bing)能(neng)促進傷(shang)(shang)(shang)口愈合和結痂。佐藥白術(shu)所含(han)白術(shu)內酯(zhi)可顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)抑(yi)制(zhi)(zhi)炎癥的(de)(de)(de)(de)(de)(de)毛(mao)細(xi)血(xue)(xue)管(guan)(guan)通透性(xing)(xing)(xing)(xing)增(zeng)(zeng)加(jia)，提(ti)(ti)(ti)高RBC中(zhong)SOD活(huo)(huo)性(xing)(xing)(xing)(xing)，增(zeng)(zeng)強(qiang)(qiang)清(qing)(qing)(qing)除(chu)自(zi)由(you)(you)(you)基(ji)(ji)(ji)的(de)(de)(de)(de)(de)(de)作(zuo)(zuo)用(yong)(yong)，減少自(zi)由(you)(you)(you)基(ji)(ji)(ji)對(dui)(dui)機體的(de)(de)(de)(de)(de)(de)損(sun)(sun)(sun)害；可顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)提(ti)(ti)(ti)高全血(xue)(xue)GSHPx活(huo)(huo)性(xing)(xing)(xing)(xing)，明(ming)顯(xian)(xian)(xian)(xian)(xian)降(jiang)低(di)(di)RBC中(zhong)MDA含(han)量(liang)，具(ju)(ju)有(you)(you)顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)抗(kang)氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)作(zuo)(zuo)用(yong)(yong)。陳皮(pi)所含(han)甲(jia)基(ji)(ji)(ji)橙皮(pi)苷可顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)抑(yi)制(zhi)(zhi)炎癥的(de)(de)(de)(de)(de)(de)毛(mao)細(xi)血(xue)(xue)管(guan)(guan)通透性(xing)(xing)(xing)(xing)增(zeng)(zeng)加(jia)，其(qi)提(ti)(ti)(ti)取物可清(qing)(qing)(qing)除(chu)超(chao)氧(yang)(yang)(yang)陰離(li)子(zi)自(zi)由(you)(you)(you)基(ji)(ji)(ji)及(ji)(ji)(ji)(ji)羥(qian)(qian)基(ji)(ji)(ji)，抑(yi)制(zhi)(zhi)自(zi)由(you)(you)(you)基(ji)(ji)(ji)引起的(de)(de)(de)(de)(de)(de)脂(zhi)(zhi)質(zhi)過氧(yang)(yang)(yang)化(hua)(hua)(hua)(hua)作(zuo)(zuo)用(yong)(yong)。山楂及(ji)(ji)(ji)(ji)山楂黃(huang)酮(tong)可顯(xian)(xian)(xian)(xian)(xian)著(zhu)(zhu)降(jiang)低(di)(di)血(xue)(xue)清(qing)(qing)(qing)中(zhong)MDA含(han)量(liang)，增(zeng)(zeng)強(qiang)(qiang)RBC及(ji)(ji)(ji)(ji)肝(gan)臟SOD活(huo)(huo)性(xing)(xing)(xing)(xing)，增(zeng)(zeng)強(qiang)(qiang)全血(xue)(xue)GSHPx活(huo)(huo)性(xing)(xing)(xing)(xing)。
由(you)以(yi)上可以(yi)看出該方劑具(ju)(ju)有顯著的抗(kang)炎作用，特別是具(ju)(ju)有抗(kang)氧(yang)化(hua)損(sun)傷作用。
人體體表面積計算器BMI指數計算及評價女性安全期計算器預產期計算器孕期體重增長正常值孕期用藥安全性分級（FDA）五行八字成人血壓評價體溫水平評價糖尿病飲食建議臨床生化常用單位換算基礎代謝率計算補鈉計算器補鐵計算器處方常用拉丁文縮寫速查藥代動力學常用符號速查有效血漿滲透壓計算器乙醇攝入量計算器
醫學(xue)百科，馬上計算(suan)！
3.7.7其他
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