日前,第四軍醫大學西京醫院心臟內科沈敏博士等完成的一項研究證明,白藜蘆醇(RVT)是有(you)效的舒血管物質。
RVT屬(shu)于一種酚類植物抗毒素,是天然的(de)抗氧化物和(he)(he)自(zi)由基廓清劑,主要存在(zai)于各(ge)種紅(hong)(hong)葡萄果實和(he)(he)紅(hong)(hong)葡萄酒中(zhong)。在(zai)早期的(de)一項關于飲食習慣與冠心(xin)病(bing)發病(bing)率(lv)的(de)流行病(bing)學研究中(zhong),人(ren)們發現(xian)了一個有趣的(de)現(xian)象,即在(zai)所有發達國(guo)家(jia)中(zhong),法國(guo)人(ren)飲用紅(hong)(hong)葡萄酒的(de)平(ping)均量最大,但是其冠心(xin)病(bing)發病(bing)率(lv)最低,這主要得益(yi)于紅(hong)(hong)葡萄酒中(zhong)的(de)RVT。RVT可以(yi)提高外周(zhou)血(xue)液中(zhong)高密度脂(zhi)蛋白的(de)含(han)量,降低血(xue)小板的(de)凝集(ji)活性,防止血(xue)栓(shuan)的(de)形成和(he)(he)動脈粥樣硬化的(de)發生。
為研(yan)究(jiu)RVT對大鼠腹主(zhu)動脈離體血(xue)管(guan)(guan)的(de)舒張作用特點(dian)并探討其機制,沈敏博士(shi)等將(jiang)20只SD大鼠頸(jing)椎脫位處死后,迅(xun)速(su)取出腹主(zhu)動脈,把血(xue)管(guan)(guan)制備成(cheng)長約(yue)3毫(hao)米的(de)血(xue)管(guan)(guan)環標本,并隨機分為7組(zu),即RVT濃度(du)依賴組(zu)、內皮(pi)依賴組(zu)、L-NAME組(zu)、優降糖(tang)組(zu)、阿托(tuo)品組(zu)、普萘洛爾組(zu)、消炎痛組(zu),每組(zu)均含6例樣本,測(ce)定血(xue)管(guan)(guan)環張力的(de)變化。
RVT濃度依賴(lai)組分別(bie)對內(nei)(nei)皮(pi)完整(zheng)及去內(nei)(nei)皮(pi)血(xue)(xue)管(guan)做(zuo)濃度依賴(lai)曲線,研究結(jie)果顯(xian)示(shi),RVT在(zai)(zai)4×10-9~4×10-5摩(mo)爾/升范圍(wei)內(nei)(nei),對腹主動脈(mo)具(ju)有劑量(liang)依賴(lai)性的(de)舒(shu)(shu)血(xue)(xue)管(guan)效應。RVT在(zai)(zai)4×10-5摩(mo)爾/升的(de)濃度時,即可完全舒(shu)(shu)張內(nei)(nei)皮(pi)完整(zheng)血(xue)(xue)管(guan);舒(shu)(shu)張血(xue)(xue)管(guan)效應在(zai)(zai)血(xue)(xue)管(guan)去內(nei)(nei)皮(pi)后可降(jiang)低(74.9±1.9)%,與內(nei)(nei)皮(pi)完整(zheng)組相比,有顯(xian)著性差異(P
在(zai)L-NAME組(zu)(zu)和優降(jiang)糖組(zu)(zu)中,舒血管效應(ying)分別(bie)降(jiang)低(79.8±3.7)%和(43.8±2.8)%,與內皮完整組(zu)(zu)相比,兩組(zu)(zu)均存(cun)在(zai)顯著性差異(P0.05)。
研究結果顯示(shi),RVT是一種(zhong)有(you)效(xiao)的(de)(de)舒(shu)血(xue)(xue)管物質,具有(you)內皮依(yi)賴性和非(fei)內皮依(yi)賴性的(de)(de)舒(shu)血(xue)(xue)管效(xiao)應(ying),前者的(de)(de)作用機制(zhi)與NO系統和ATP敏(min)感的(de)(de)鉀通(tong)道有(you)關,而后者可能(neng)是由于RVT對血(xue)(xue)管的(de)(de)直接(jie)作用引起的(de)(de)。
第四軍醫大學西京醫院 三甲 長樂西路 15 號
西安交通大學第一附屬醫院 三甲健康路 1 號
西安交通大學第二附屬醫院三甲 西五路 36 號
陜西省人民醫院 三甲 友誼西路 214 號
西安市中心醫院 三甲 后宰門 4 號
西安市第一醫院 三甲 粉巷 114 號
西安市第四醫院 三甲 解放路 13 號
解放軍第 323 醫院三甲建設西路 6 號
解放軍第 451 醫院 三甲 友誼東路 39 號
第四軍醫大學唐都醫院三甲東郊新寺路
武警醫院 三甲南二環東段
長安醫院 三甲(相當)經濟開發區方景路 17 號
高新(xin)醫院 三(san)甲(相當)高新(xin)技(ji)術開發(fa)區(qu)團結(jie)南(nan)路
超聲消融手術主要包括(kuo):超聲聚焦刀(俗稱(cheng)“海(hai)扶刀”)和超聲刀兩種。
超聲聚焦刀(dao)(俗(su)稱(cheng)“海扶刀(dao)”)治(zhi)療各類(lei)實體良惡性腫(zhong)瘤(liu)(如肝癌,乳(ru)腺癌,子(zi)宮肌瘤(liu))的一種(zhong)治(zhi)療方(fang)法。
基本介紹中文名 :超聲消融手術 組成 :超聲聚焦刀,超聲刀 特點 :圖像監控 優勢 :非侵入性治療 治療原理,治療特點,治療優勢,主要醫院,超聲刀,治療原理利用超音波可通過人體組織,并聚焦在特定靶區的特性,將能量聚集到足夠的強度,使焦點區域達到瞬間高溫,破壞靶區組織,在組織病理學上表現為凝固性壞死,也叫消融。從而達到破壞病變區域的目的,而病變區域外的組織沒有損傷。治療特點⑴ 圖像監控:實時監控超聲圖像用來確定計畫選定的目標腫瘤。整個治療過程由系統控制,并及時提供治療效果反饋。 ⑵ 準確性:焦點處的能量能使焦點處組織產生凝固性壞死,且對周圍組織或聲通道上的組織沒有損傷。治療區與非治療區的邊界只有6到10個細胞的寬度。 ⑶ 自由運動:焦點及監控探頭在空間的自由運動,可實現立體組合掃描治療,醫師可根據不同患者、不同腫瘤選擇快速、靈活而有效的治療方案。 ⑷ 徹底治療:聚焦超聲腫瘤治療系統的治療計畫軟體能夠幫助醫師準確鎖定并切除整個腫瘤組織。對可能治療的腫瘤體積沒有上限。 ⑸ 可控治療:在整個治療過程中,實時影像技術可為醫師提供視頻反饋,根據數位化的灰度變化隨時調整治療劑量。治療優勢整個治療過程無創傷、不出血、不需麻醉,真正實現從體外治療體內的腫瘤,殺滅腫瘤組織。治療過程中通過移動超聲治療頭,改變超音波的聚焦深度,采用:點-線-面-體的組合掃描方式,對整個肌瘤進行適形消融。 1 、非侵入性治療體外操作,完整破壞體內病灶; 不開刀、無放射性損害; 不需手術暴露或穿刺引導; 不損傷超音波所經過的組織或靶區外正常結構。 2 、總費用低的治療明顯縮短病人住院時間; 治療時不輸血; 明顯減少病人在外科手術中、術后的并發癥 病人的痛苦小, 治療后機體恢復快; 減少了術后廣譜抗菌素的套用。 3 、劑量均勻分布的治療體外掃描治療,使靶區內超聲能量分布均勻; 解決了微創介入治療(微波、射頻、雷射、冷凍等)依靠治療頭進行能量擴散,治療劑量分布不均勻的難題 4 、靶區組織致死性治療靶區內均為超音波的致死劑量,非選擇性使靶區內任何組織完全毀損; 根據手術切除原則,從體外"切除"體內病灶。 5 、適形的治療立體組合適形掃描治療方式充分保證從體外完整地破壞體內病灶; 不受腫瘤形狀的限制。 6 、不受腫瘤大小限制的治療可以完全破壞體內任意大小的癌塊。 7 、選擇性破壞血管的治療一般情況下,僅破壞腫瘤內直徑2mm以下的血管,有效保證治療的安全性; 增加病灶的可治療范圍,使因血管解剖因素致部分不能接受外科手術的腫瘤病人的局部治療成為可能;促進局部正常組織的修復 8 、實時的治療治療時對腫瘤進行立體定位; 超聲監控裝置實時地監控整個治療過程,有效防止脫靶發生。 實時的治療。 9 、實時判斷療效的治療治療過程中,通過治療前、治療中和治療后靶區聲像圖的變化,及時地評價治療區域內組織是否出現凝固性壞死和皮膚有無損傷。 10 、劑量受控制的治療通過實時地判斷靶區的療效,反饋性控制治療劑量,使靶區內致死劑量均勻分布。主要醫院 ·中國人民解放軍總醫院(北京301醫院) ·中國人民解放軍307醫院 ·重慶醫科大學附屬第一醫院 ·重慶醫科大學附屬第二醫院 ·重慶三峽中心醫院 ·第四軍醫大學附屬(西安)西京醫院 ·黑龍江省雞西市人民醫院 ·河南大學附屬(南陽)南石醫院 ·廣東醫學院附屬(深圳市)福田醫院 ·香港瑪麗醫院 ·英國牛津大學邱吉爾醫院 ·歐洲癌癥中心 ·俄羅斯國家醫學外科中心 ·義大利匹薩大學Cisanello醫院 ·日本千葉大學醫學部附屬醫院 ·西班牙HMT醫院 ·俄羅斯中央銀行醫院 ·韓國汝矣島圣母醫院超聲消融治療中心 ·日本Clinica E.T診所超聲消融治療中心 ·義大利羅馬美國醫院超聲消融治療中心超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)并(bing)不(bu)(bu)(bu)(bu)是(shi)(shi)(shi)我(wo)們平(ping)時(shi)(shi)看(kan)到(dao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)把刀(dao)(dao)(dao)(dao)(dao)(dao)(dao),它(ta)(ta)(ta)是(shi)(shi)(shi)利用(yong)(yong)(yong)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)原(yuan)理(li)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)像真(zhen)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)樣切割人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)內(nei)(nei)部(bu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)音(yin)波(bo)(bo). 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)原(yuan)理(li)是(shi)(shi)(shi): 它(ta)(ta)(ta)利用(yong)(yong)(yong)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)音(yin)波(bo)(bo)極強(qiang)(qiang)(qiang)(qiang)(qiang)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)穿透(tou)力(li),通(tong)(tong)(tong)過(guo)(guo)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)發(fa)(fa)射器發(fa)(fa)射的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)數(shu)(shu)百束高(gao)(gao)(gao)(gao)(gao)(gao)(gao)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)音(yin)波(bo)(bo)(相(xiang)(xiang)當于(yu) 5 萬臺(tai)普通(tong)(tong)(tong) B 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)機(ji)) , 像聚(ju)(ju)集太陽能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)樣使(shi)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)點(dian)匯(hui)集在(zai)(zai)(zai)(zai)(zai)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)上(shang),利用(yong)(yong)(yong)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)空化(hua)(hua)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)使(shi)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)膜(mo)破(po)裂,同(tong)(tong)時(shi)(shi)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)音(yin)波(bo)(bo)釋放(fang)(fang)出(chu)巨(ju)大(da)(da)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)量迅(xun)速(su)轉(zhuan)化(hua)(hua)為(wei)熱(re)(re)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng),瞬間(jian)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)點(dian)處(chu)(chu)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)溫(wen)(wen)度(du)(du)(du)(du)達(da)(da) 70 ℃ -100 ℃ 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)這(zhe)樣識別(bie)(bie)和(he)(he)鎖(suo)定(ding)(ding)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu): 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)擁(yong)有(you)(you)(you)(you)(you)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)套腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)識別(bie)(bie)系(xi)(xi)統(tong)(tong)(tong),它(ta)(ta)(ta)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)準確(que)(que)探測到(dao)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)部(bu)位(wei)和(he)(he)大(da)(da)小,然(ran)后(hou)把這(zhe)些(xie)影像信(xin)息(xi)傳(chuan)遞到(dao)計算機(ji)中(zhong),計算機(ji)在(zai)(zai)(zai)(zai)(zai)接收(shou)(shou)到(dao)這(zhe)些(xie)信(xin)息(xi)后(hou)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)自(zi)(zi)動(dong)鎖(suo)定(ding)(ding)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu),在(zai)(zai)(zai)(zai)(zai)計算機(ji)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)控制下,超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)音(yin)波(bo)(bo)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)毫(hao)無(wu)(wu)損傷(shang)(shang)地穿過(guo)(guo)人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)正(zheng)常組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)到(dao)達(da)(da)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)上(shang),既能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)殺(sha)死(si)(si)(si)(si)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao),又不(bu)(bu)(bu)(bu)傷(shang)(shang)及(ji)(ji)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)周(zhou)(zhou)圍(wei)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)正(zheng)常組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)。 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)和(he)(he)適應(ying)(ying)癥(zheng)(zheng)(zheng)是(shi)(shi)(shi): 主要(yao)適應(ying)(ying)腹部(bu)、盆(pen)腔(qiang)和(he)(he)體(ti)(ti)(ti)(ti)(ti)表(biao)各種腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)。主要(yao)包(bao)(bao)括:胰(yi)腺(xian)(xian)癌(ai)(ai)(ai)(ai)、肝癌(ai)(ai)(ai)(ai)、腎及(ji)(ji)腎上(shang)腺(xian)(xian)良(liang)惡性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)、胃(wei)癌(ai)(ai)(ai)(ai)、直(zhi)腸(chang)癌(ai)(ai)(ai)(ai)、結腸(chang)癌(ai)(ai)(ai)(ai)、前(qian)列腺(xian)(xian)癌(ai)(ai)(ai)(ai)、前(qian)列腺(xian)(xian)增(zeng)生(sheng)(sheng)(sheng)、膀胱癌(ai)(ai)(ai)(ai)、子(zi)宮(gong)癌(ai)(ai)(ai)(ai)、子(zi)宮(gong)肌瘤(liu)(liu)(liu)(liu)(liu)(liu)、卵(luan)巢(chao)癌(ai)(ai)(ai)(ai)、各種腹部(bu)及(ji)(ji)盆(pen)腔(qiang)轉(zhuan)移癌(ai)(ai)(ai)(ai)等(deng)(deng)。 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)對(dui)(dui)人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)無(wu)(wu)損害(hai),其原(yuan)因(yin)是(shi)(shi)(shi): 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)音(yin)波(bo)(bo)是(shi)(shi)(shi)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)種機(ji)械波(bo)(bo),不(bu)(bu)(bu)(bu)含放(fang)(fang)射線,對(dui)(dui)人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)無(wu)(wu)任(ren)何傷(shang)(shang)害(hai)。超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)是(shi)(shi)(shi)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)種無(wu)(wu)創傷(shang)(shang)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)方(fang)(fang)(fang)法(fa),治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)時(shi)(shi)不(bu)(bu)(bu)(bu)開刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)、 *** 刺,患(huan)者(zhe)在(zai)(zai)(zai)(zai)(zai)接受治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)時(shi)(shi)毫(hao)無(wu)(wu)痛(tong)苦。 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)優點(dian)有(you)(you)(you)(you)(you): 不(bu)(bu)(bu)(bu)開刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)、 *** 刺、不(bu)(bu)(bu)(bu)流血(xue)、無(wu)(wu)任(ren)何創傷(shang)(shang),不(bu)(bu)(bu)(bu)麻醉(zui)。療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)效(xiao)(xiao)(xiao)(xiao)可(ke)(ke)(ke)(ke)靠。與(yu)(yu)(yu)手(shou)術(shu)(shu)(shu)(shu)(shu),化(hua)(hua)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)、放(fang)(fang)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)聯合(he)套用(yong)(yong)(yong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)獲(huo)最佳治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)效(xiao)(xiao)(xiao)(xiao)果(guo)。 實(shi)體(ti)(ti)(ti)(ti)(ti)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)新途徑(jing)──高(gao)(gao)(gao)(gao)(gao)(gao)(gao)強(qiang)(qiang)(qiang)(qiang)(qiang)度(du)(du)(du)(du)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)儀(yi)(yi) 高(gao)(gao)(gao)(gao)(gao)(gao)(gao)強(qiang)(qiang)(qiang)(qiang)(qiang)度(du)(du)(du)(du)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)技術(shu)(shu)(shu)(shu)(shu)是(shi)(shi)(shi)上(shang)世(shi)紀40年(nian)代興(xing)起(qi)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)項超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)外(wai)科治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)技術(shu)(shu)(shu)(shu)(shu),它(ta)(ta)(ta)通(tong)(tong)(tong)過(guo)(guo)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)定(ding)(ding)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)方(fang)(fang)(fang)式,將超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)音(yin)波(bo)(bo)發(fa)(fa)出(chu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)量聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)于(yu)人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi),在(zai)(zai)(zai)(zai)(zai)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)內(nei)(nei)形成一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)個聲(sheng)(sheng)(sheng)(sheng)(sheng)強(qiang)(qiang)(qiang)(qiang)(qiang)較(jiao)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)區(qu)(qu)(qu)(qu)域(yu)———焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)域(yu),使(shi)其中(zhong)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)在(zai)(zai)(zai)(zai)(zai)0.5—5秒內(nei)(nei)溫(wen)(wen)度(du)(du)(du)(du)達(da)(da)到(dao)70℃以(yi)上(shang),致(zhi)(zhi)(zhi) 使(shi)這(zhe)些(xie)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)凝(ning)(ning)固(gu)(gu)壞(huai)(huai)死(si)(si)(si)(si)而(er)又不(bu)(bu)(bu)(bu)損傷(shang)(shang)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)域(yu)外(wai)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)正(zheng)常組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi),從(cong)而(er)進(jin)行腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)。這(zhe)種非侵(qin)入性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)方(fang)(fang)(fang)法(fa)避免(mian)了放(fang)(fang)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)、化(hua)(hua)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)毒(du)副(fu)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)及(ji)(ji)放(fang)(fang)射性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)積(ji)累問(wen)題,同(tong)(tong)時(shi)(shi)可(ke)(ke)(ke)(ke)避免(mian)手(shou)術(shu)(shu)(shu)(shu)(shu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)痛(tong)苦和(he)(he)傷(shang)(shang)害(hai),特(te)別(bie)(bie)適用(yong)(yong)(yong)于(yu)深部(bu)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)病(bing)灶和(he)(he)不(bu)(bu)(bu)(bu)適于(yu)手(shou)術(shu)(shu)(shu)(shu)(shu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)病(bing)人(ren)(ren),受 到(dao)醫(yi)患(huan)歡(huan)迎。在(zai)(zai)(zai)(zai)(zai)國(guo)(guo)外(wai),該產(chan)(chan)品的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)開發(fa)(fa)目(mu)前(qian)處(chu)(chu)于(yu)技術(shu)(shu)(shu)(shu)(shu)研(yan)究(jiu)和(he)(he)臨(lin)(lin)(lin)床(chuang)階段(duan)(duan),尚未形成商品。 據(ju)專家(jia)介紹,這(zhe)套系(xi)(xi)統(tong)(tong)(tong)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)創新點(dian)在(zai)(zai)(zai)(zai)(zai)于(yu)6片球形凹面(mian)(mian)壓(ya)電陶瓷片拼接成半球形凹面(mian)(mian)自(zi)(zi)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)換能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)器陣,采(cai)用(yong)(yong)(yong)聲(sheng)(sheng)(sheng)(sheng)(sheng)匹配、第一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)泛(fan)音(yin)頻工作(zuo)(zuo)(zuo)(zuo)及(ji)(ji)特(te)種三(san)維(wei)曲(qu)面(mian)(mian)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)換能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)器新技術(shu)(shu)(shu)(shu)(shu),獲(huo)得(de)(de)較(jiao)好的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)場和(he)(he)電聲(sheng)(sheng)(sheng)(sheng)(sheng)轉(zhuan)換效(xiao)(xiao)(xiao)(xiao)率;國(guo)(guo)內(nei)(nei)首創的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)三(san)維(wei)重(zhong)建、計算 機(ji)輔助(zhu)干(gan)預(CAMI)技術(shu)(shu)(shu)(shu)(shu)和(he)(he)消融鑒別(bie)(bie)技術(shu)(shu)(shu)(shu)(shu)套用(yong)(yong)(yong)于(yu)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)強(qiang)(qiang)(qiang)(qiang)(qiang)度(du)(du)(du)(du)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng),有(you)(you)(you)(you)(you)效(xiao)(xiao)(xiao)(xiao)提(ti)(ti)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)了腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)有(you)(you)(you)(you)(you)效(xiao)(xiao)(xiao)(xiao)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)和(he)(he)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)效(xiao)(xiao)(xiao)(xiao)評估;多個自(zi)(zi)由度(du)(du)(du)(du)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)精確(que)(que)定(ding)(ding)位(wei)和(he)(he)成像,確(que)(que)保產(chan)(chan)品的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)準確(que)(que)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing);具有(you)(you)(you)(you)(you)系(xi)(xi)統(tong)(tong)(tong)聲(sheng)(sheng)(sheng)(sheng)(sheng)場自(zi)(zi)檢(jian)(jian)功(gong)(gong)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng),啟(qi)動(dong)系(xi)(xi)統(tong)(tong)(tong)聲(sheng)(sheng)(sheng)(sheng)(sheng)場自(zi)(zi)動(dong)測量軟體(ti)(ti)(ti)(ti)(ti),可(ke)(ke)(ke)(ke)提(ti)(ti)供聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)聲(sheng)(sheng)(sheng)(sheng)(sheng)場參 數(shu)(shu)。項目(mu)已(yi)經獲(huo)得(de)(de)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)項國(guo)(guo)家(jia)發(fa)(fa)明專利。 一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)、治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)原(yuan)理(li) HIFU的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)主要(yao)通(tong)(tong)(tong)過(guo)(guo)幾個方(fang)(fang)(fang)面(mian)(mian)進(jin)行的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)。 1.高(gao)(gao)(gao)(gao)(gao)(gao)(gao)熱(re)(re)效(xiao)(xiao)(xiao)(xiao)應(ying)(ying):通(tong)(tong)(tong)常情況下腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)致(zhi)(zhi)(zhi)死(si)(si)(si)(si)溫(wen)(wen)度(du)(du)(du)(du)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)臨(lin)(lin)(lin)界點(dian)在(zai)(zai)(zai)(zai)(zai)42.5~43.0℃,而(er)正(zheng)常細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)則(ze)為(wei)45℃,對(dui)(dui)于(yu)肝臟組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)而(er)言,局(ju)(ju)部(bu)溫(wen)(wen)度(du)(du)(du)(du)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)過(guo)(guo)58℃即可(ke)(ke)(ke)(ke)致(zhi)(zhi)(zhi)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)凝(ning)(ning)固(gu)(gu)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)壞(huai)(huai)死(si)(si)(si)(si)。區(qu)(qu)(qu)(qu)別(bie)(bie)于(yu)低功(gong)(gong)率聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng),HIFU治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)儀(yi)(yi)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)將高(gao)(gao)(gao)(gao)(gao)(gao)(gao)強(qiang)(qiang)(qiang)(qiang)(qiang)度(du)(du)(du)(du)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)于(yu)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)區(qu)(qu)(qu)(qu)域(yu),能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)在(zai)(zai)(zai)(zai)(zai) 0.5秒內(nei)(nei)迅(xun)速(su)將目(mu)標區(qu)(qu)(qu)(qu)域(yu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)溫(wen)(wen)度(du)(du)(du)(du)驟升至70℃以(yi)上(shang),從(cong)而(er)使(shi)得(de)(de)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)區(qu)(qu)(qu)(qu)域(yu)內(nei)(nei)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)內(nei)(nei)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)蛋白迅(xun)速(su)出(chu)現凝(ning)(ning)固(gu)(gu)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)壞(huai)(huai)死(si)(si)(si)(si),產(chan)(chan)生(sheng)(sheng)(sheng)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)。 2.空化(hua)(hua)效(xiao)(xiao)(xiao)(xiao)應(ying)(ying):通(tong)(tong)(tong)過(guo)(guo)氣泡的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)強(qiang)(qiang)(qiang)(qiang)(qiang)烈膨脹和(he)(he)萎縮(suo)運動(dong),使(shi)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)產(chan)(chan)生(sheng)(sheng)(sheng)機(ji)械性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)破(po)壞(huai)(huai)。 3.免(mian)疫(yi)(yi)效(xiao)(xiao)(xiao)(xiao)應(ying)(ying):壞(huai)(huai)死(si)(si)(si)(si)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi),同(tong)(tong)時(shi)(shi)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)起(qi)到(dao) *** 機(ji)體(ti)(ti)(ti)(ti)(ti)免(mian)疫(yi)(yi)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong),在(zai)(zai)(zai)(zai)(zai)后(hou)期產(chan)(chan)生(sheng)(sheng)(sheng)抗腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)效(xiao)(xiao)(xiao)(xiao)應(ying)(ying)。 二、治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)特(te)點(dian) HIFU在(zai)(zai)(zai)(zai)(zai)靶(ba)(ba)區(qu)(qu)(qu)(qu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)產(chan)(chan)生(sheng)(sheng)(sheng)凝(ning)(ning)固(gu)(gu)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)壞(huai)(huai)死(si)(si)(si)(si)灶或損傷(shang)(shang)灶,其顯(xian)著的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)特(te)點(dian)是(shi)(shi)(shi)在(zai)(zai)(zai)(zai)(zai)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)區(qu)(qu)(qu)(qu)及(ji)(ji)其以(yi)外(wai)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)區(qu)(qu)(qu)(qu)域(yu)產(chan)(chan)生(sheng)(sheng)(sheng)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)清(qing)楚的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)過(guo)(guo)渡(du)(du)帶(dai),其過(guo)(guo)渡(du)(du)區(qu)(qu)(qu)(qu)不(bu)(bu)(bu)(bu)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)過(guo)(guo)50μm,僅含有(you)(you)(you)(you)(you)5~7層的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao),對(dui)(dui)靶(ba)(ba)區(qu)(qu)(qu)(qu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)起(qi)直(zhi)接殺(sha)傷(shang)(shang)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong),而(er)對(dui)(dui)其周(zhou)(zhou)圍(wei)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)無(wu)(wu)損傷(shang)(shang)或損傷(shang)(shang)較(jiao)輕,這(zhe)是(shi)(shi)(shi)區(qu)(qu)(qu)(qu)別(bie)(bie)于(yu)其 他的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)三(san)維(wei)立(li)體(ti)(ti)(ti)(ti)(ti)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)儀(yi)(yi)如γ刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)等(deng)(deng)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(對(dui)(dui)靶(ba)(ba)區(qu)(qu)(qu)(qu)周(zhou)(zhou)圍(wei)仍具有(you)(you)(you)(you)(you)很大(da)(da)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)損傷(shang)(shang))。 在(zai)(zai)(zai)(zai)(zai)動(dong)物肝臟中(zhong)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)研(yan)究(jiu)發(fa)(fa)現在(zai)(zai)(zai)(zai)(zai)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)域(yu)中(zhong)心(xin)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)溫(wen)(wen)度(du)(du)(du)(du)最高(gao)(gao)(gao)(gao)(gao)(gao)(gao),可(ke)(ke)(ke)(ke)達(da)(da) 53℃。此(ci)溫(wen)(wen)度(du)(du)(du)(du)完(wan)全(quan)(quan)可(ke)(ke)(ke)(ke)使(shi)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)蛋白質(zhi)變性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing),靶(ba)(ba)區(qu)(qu)(qu)(qu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)發(fa)(fa)生(sheng)(sheng)(sheng)凝(ning)(ning)固(gu)(gu)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)壞(huai)(huai)死(si)(si)(si)(si)。在(zai)(zai)(zai)(zai)(zai)離(li)體(ti)(ti)(ti)(ti)(ti)肝組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)中(zhong),在(zai)(zai)(zai)(zai)(zai)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)定(ding)(ding)聲(sheng)(sheng)(sheng)(sheng)(sheng)強(qiang)(qiang)(qiang)(qiang)(qiang)下,輻(fu)照(zhao)時(shi)(shi)間(jian)越長、焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)域(yu)中(zhong)心(xin)溫(wen)(wen)度(du)(du)(du)(du)越高(gao)(gao)(gao)(gao)(gao)(gao)(gao)、生(sheng)(sheng)(sheng)物學焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)域(yu)亦越大(da)(da),但(dan)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)域(yu)外(wai)緣(yuan)溫(wen)(wen) 升區(qu)(qu)(qu)(qu)大(da)(da)致(zhi)(zhi)(zhi)相(xiang)(xiang)同(tong)(tong) (均(jun)為(wei) 4.5mm) 。解剖及(ji)(ji)病(bing)理(li)學檢(jian)(jian)查亦證實(shi)損傷(shang)(shang)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)與(yu)(yu)(yu)其周(zhou)(zhou)圍(wei)正(zheng)常組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)分(fen)界線清(qing)楚。在(zai)(zai)(zai)(zai)(zai)活(huo)(huo)體(ti)(ti)(ti)(ti)(ti)肝組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)中(zhong),距(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)域(yu)外(wai)圍(wei) 2.5mm處(chu)(chu),溫(wen)(wen)度(du)(du)(du)(du)正(zheng)常。活(huo)(huo)體(ti)(ti)(ti)(ti)(ti)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)溫(wen)(wen)升區(qu)(qu)(qu)(qu)較(jiao)離(li)體(ti)(ti)(ti)(ti)(ti)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)窄,可(ke)(ke)(ke)(ke)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)是(shi)(shi)(shi)活(huo)(huo)體(ti)(ti)(ti)(ti)(ti)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)通(tong)(tong)(tong)過(guo)(guo)靶(ba)(ba)區(qu)(qu)(qu)(qu)周(zhou)(zhou)圍(wei)血(xue)流散熱(re)(re)所致(zhi)(zhi)(zhi)。此(ci)結果(guo) 提(ti)(ti)示:HIFU可(ke)(ke)(ke)(ke)有(you)(you)(you)(you)(you)效(xiao)(xiao)(xiao)(xiao)地損傷(shang)(shang)靶(ba)(ba)區(qu)(qu)(qu)(qu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi),而(er)周(zhou)(zhou)圍(wei)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)不(bu)(bu)(bu)(bu)受影響(xiang)(xiang)或影響(xiang)(xiang)較(jiao)小[4]。 正(zheng)是(shi)(shi)(shi)由于(yu)靶(ba)(ba)區(qu)(qu)(qu)(qu)內(nei)(nei)外(wai)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)效(xiao)(xiao)(xiao)(xiao)應(ying)(ying)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)不(bu)(bu)(bu)(bu)同(tong)(tong),使(shi)得(de)(de)HIFU治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)具有(you)(you)(you)(you)(you)以(yi)下的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)特(te)點(dian)。優點(dian):(1) 無(wu)(wu)創傷(shang)(shang)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing):只對(dui)(dui)靶(ba)(ba)區(qu)(qu)(qu)(qu)內(nei)(nei)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)產(chan)(chan)生(sheng)(sheng)(sheng)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong),其臨(lin)(lin)(lin)近組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)及(ji)(ji)臟器不(bu)(bu)(bu)(bu)受影響(xiang)(xiang)。(2) 可(ke)(ke)(ke)(ke)監(jian)測性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing):治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)過(guo)(guo)程中(zhong),可(ke)(ke)(ke)(ke)通(tong)(tong)(tong)過(guo)(guo)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)后(hou)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)壞(huai)(huai)死(si)(si)(si)(si)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)聲(sheng)(sheng)(sheng)(sheng)(sheng)影的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)改變,監(jian)測治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)效(xiao)(xiao)(xiao)(xiao)果(guo)。 副(fu)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong):很少,僅有(you)(you)(you)(you)(you)少數(shu)(shu)產(chan)(chan)生(sheng)(sheng)(sheng)皮膚(fu)損傷(shang)(shang)。 三(san)、適應(ying)(ying)癥(zheng)(zheng)(zheng)廣(guang)。在(zai)(zai)(zai)(zai)(zai)距(ju)離(li)體(ti)(ti)(ti)(ti)(ti)表(biao)3-15cm深度(du)(du)(du)(du)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de),絕大(da)(da)多數(shu)(shu)腹腔(qiang)盆(pen)腔(qiang)及(ji)(ji)體(ti)(ti)(ti)(ti)(ti)表(biao)等(deng)(deng)處(chu)(chu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)實(shi)體(ti)(ti)(ti)(ti)(ti)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)均(jun)可(ke)(ke)(ke)(ke)實(shi)施超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao);對(dui)(dui)于(yu)年(nian)老(lao)體(ti)(ti)(ti)(ti)(ti)弱,或具有(you)(you)(you)(you)(you)明顯(xian)全(quan)(quan)身其它(ta)(ta)(ta)臟器(如肝、腎、胰(yi)等(deng)(deng))并(bing)發(fa)(fa)癥(zheng)(zheng)(zheng)及(ji)(ji)其它(ta)(ta)(ta)明顯(xian)手(shou)術(shu)(shu)(shu)(shu)(shu)禁忌癥(zheng)(zheng)(zheng)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)患(huan)者(zhe)也可(ke)(ke)(ke)(ke)施行治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao);對(dui)(dui)與(yu)(yu)(yu)中(zhong)晚期 腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu),除(chu)(chu)可(ke)(ke)(ke)(ke)以(yi)局(ju)(ju)部(bu)殺(sha)死(si)(si)(si)(si)原(yuan)發(fa)(fa)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)外(wai),還可(ke)(ke)(ke)(ke)以(yi)結合(he)放(fang)(fang)、化(hua)(hua)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)方(fang)(fang)(fang)法(fa),以(yi)提(ti)(ti)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)放(fang)(fang)、化(hua)(hua)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)效(xiao)(xiao)(xiao)(xiao)果(guo);對(dui)(dui)手(shou)術(shu)(shu)(shu)(shu)(shu)無(wu)(wu)法(fa)切除(chu)(chu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu),對(dui)(dui)放(fang)(fang)、化(hua)(hua)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)不(bu)(bu)(bu)(bu)敏感,或術(shu)(shu)(shu)(shu)(shu)后(hou)復(fu)發(fa)(fa)不(bu)(bu)(bu)(bu)愿再次接受手(shou)術(shu)(shu)(shu)(shu)(shu)切除(chu)(chu),此(ci)時(shi)(shi),高(gao)(gao)(gao)(gao)(gao)(gao)(gao)強(qiang)(qiang)(qiang)(qiang)(qiang)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)可(ke)(ke)(ke)(ke)以(yi)使(shi)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)實(shi)體(ti)(ti)(ti)(ti)(ti)縮(suo)小或壞(huai)(huai)死(si)(si)(si)(si) ,有(you)(you)(you)(you)(you)利于(yu)緩(huan)解癥(zheng)(zheng)(zheng)狀,改善(shan)(shan)病(bing)人(ren)(ren)生(sheng)(sheng)(sheng)存狀況,提(ti)(ti)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)肌體(ti)(ti)(ti)(ti)(ti)免(mian)疫(yi)(yi)力(li)和(he)(he)患(huan)者(zhe)生(sheng)(sheng)(sheng)活(huo)(huo)質(zhi)量。 高(gao)(gao)(gao)(gao)(gao)(gao)(gao)強(qiang)(qiang)(qiang)(qiang)(qiang)度(du)(du)(du)(du)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)系(xi)(xi)統(tong)(tong)(tong)(HIFU俗稱超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao))是(shi)(shi)(shi)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)種能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)從(cong)體(ti)(ti)(ti)(ti)(ti)外(wai)使(shi)體(ti)(ti)(ti)(ti)(ti)內(nei)(nei)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)凝(ning)(ning)固(gu)(gu)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)壞(huai)(huai)死(si)(si)(si)(si)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)熱(re)(re)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)方(fang)(fang)(fang)法(fa)。它(ta)(ta)(ta)通(tong)(tong)(tong)過(guo)(guo)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)把超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)量聚(ju)(ju)集在(zai)(zai)(zai)(zai)(zai)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)點(dian),使(shi)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)點(dian)處(chu)(chu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)溫(wen)(wen)度(du)(du)(du)(du)驟然(ran)升高(gao)(gao)(gao)(gao)(gao)(gao)(gao)(65℃—100℃),通(tong)(tong)(tong)過(guo)(guo)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)溫(wen)(wen)來破(po)壞(huai)(huai)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi),可(ke)(ke)(ke)(ke)達(da)(da)到(dao)殺(sha)滅腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)目(mu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de),而(er)其周(zhou)(zhou)圍(wei)正(zheng)常組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)不(bu)(bu)(bu)(bu)受影響(xiang)(xiang)。 超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)音(yin)波(bo)(bo)在(zai)(zai)(zai)(zai)(zai)人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)傳(chuan)播時(shi)(shi),超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)量被(bei)人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)吸收(shou)(shou)后(hou)轉(zhuan)化(hua)(hua)為(wei)熱(re)(re)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(曬太陽時(shi)(shi),則(ze)是(shi)(shi)(shi)光波(bo)(bo)被(bei)人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)吸收(shou)(shou)轉(zhuan)化(hua)(hua)為(wei)熱(re)(re)能(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)(neng)),正(zheng)常人(ren)(ren)體(ti)(ti)(ti)(ti)(ti)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)可(ke)(ke)(ke)(ke)以(yi)通(tong)(tong)(tong)過(guo)(guo)有(you)(you)(you)(you)(you)效(xiao)(xiao)(xiao)(xiao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)血(xue)液循(xun)環帶(dai)走大(da)(da)部(bu)分(fen)熱(re)(re)量,因(yin)而(er)正(zheng)常組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)溫(wen)(wen)度(du)(du)(du)(du)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)變化(hua)(hua)比較(jiao)小比較(jiao)緩(huan)慢,但(dan)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)由于(yu)血(xue) 液循(xun)環量僅為(wei)正(zheng)常組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)2%—15%,血(xue)液循(xun)環很差,因(yin)為(wei)不(bu)(bu)(bu)(bu)耐熱(re)(re),溫(wen)(wen)度(du)(du)(du)(du)變化(hua)(hua)顯(xian)著。腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)這(zhe)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)特(te)點(dian)使(shi)其成為(wei)“超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)”極好的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)靶(ba)(ba)目(mu)標。 “超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)刀(dao)(dao)(dao)(dao)(dao)(dao)(dao)”治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)時(shi)(shi)一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)方(fang)(fang)(fang)面(mian)(mian)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)發(fa)(fa)生(sheng)(sheng)(sheng)凝(ning)(ning)固(gu)(gu)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)壞(huai)(huai)死(si)(si)(si)(si);另一(yi)(yi)(yi)(yi)(yi)(yi)(yi)(yi)方(fang)(fang)(fang)面(mian)(mian)其自(zi)(zi)身的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)供血(xue)血(xue)管(guan)也處(chu)(chu)于(yu)閉塞凝(ning)(ning)固(gu)(gu)狀態,使(shi)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)失去營養,兩方(fang)(fang)(fang)面(mian)(mian)因(yin)素協同(tong)(tong)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong),最終導致(zhi)(zhi)(zhi)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)細(xi)(xi)(xi)(xi)胞(bao)(bao)(bao)死(si)(si)(si)(si)亡,并(bing)逐漸(jian)被(bei)機(ji)體(ti)(ti)(ti)(ti)(ti)消化(hua)(hua)吸收(shou)(shou)。 高(gao)(gao)(gao)(gao)(gao)(gao)(gao)強(qiang)(qiang)(qiang)(qiang)(qiang)度(du)(du)(du)(du)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)技術(shu)(shu)(shu)(shu)(shu)與(yu)(yu)(yu)其他治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)手(shou)段(duan)(duan)相(xiang)(xiang)比,優點(dian)是(shi)(shi)(shi):1.無(wu)(wu)外(wai)科手(shou)術(shu)(shu)(shu)(shu)(shu)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)創傷(shang)(shang)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)。2.溫(wen)(wen)度(du)(du)(du)(du)高(gao)(gao)(gao)(gao)(gao)(gao)(gao),升溫(wen)(wen)快,聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)準確(que)(que),腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)組(zu)(zu)(zu)(zu)(zu)(zu)織(zhi)(zhi)(zhi)(zhi)瞬間(jian)凝(ning)(ning)固(gu)(gu)壞(huai)(huai)死(si)(si)(si)(si)。3.無(wu)(wu)放(fang)(fang)射線損傷(shang)(shang),不(bu)(bu)(bu)(bu)需要(yao)防護。4.無(wu)(wu)化(hua)(hua)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)毒(du)副(fu)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)。5.與(yu)(yu)(yu)放(fang)(fang)化(hua)(hua)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)有(you)(you)(you)(you)(you)協同(tong)(tong)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)。 我(wo)國(guo)(guo)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)強(qiang)(qiang)(qiang)(qiang)(qiang)度(du)(du)(du)(du)聚(ju)(ju)焦(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)(jiao)超(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)(chao)聲(sheng)(sheng)(sheng)(sheng)(sheng)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)技術(shu)(shu)(shu)(shu)(shu)于(yu)1998年(nian)開始用(yong)(yong)(yong)于(yu)臨(lin)(lin)(lin)床(chuang),該技術(shu)(shu)(shu)(shu)(shu)在(zai)(zai)(zai)(zai)(zai)消融腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu),改善(shan)(shan)患(huan)者(zhe)臨(lin)(lin)(lin)床(chuang)癥(zheng)(zheng)(zheng)狀,提(ti)(ti)高(gao)(gao)(gao)(gao)(gao)(gao)(gao)患(huan)者(zhe)生(sheng)(sheng)(sheng)活(huo)(huo)質(zhi)量等(deng)(deng)方(fang)(fang)(fang)面(mian)(mian)起(qi)到(dao)了相(xiang)(xiang)當積(ji)極的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)作(zuo)(zuo)(zuo)(zuo)用(yong)(yong)(yong)。適用(yong)(yong)(yong)于(yu)子(zi)宮(gong)肌瘤(liu)(liu)(liu)(liu)(liu)(liu)、子(zi)宮(gong)腺(xian)(xian)肌瘤(liu)(liu)(liu)(liu)(liu)(liu)、乳腺(xian)(xian)腫(zhong)(zhong)(zhong)(zhong)(zhong)(zhong)瘤(liu)(liu)(liu)(liu)(liu)(liu)、盆(pen)腹腔(qiang)復(fu)發(fa)(fa)及(ji)(ji)轉(zhuan)移性(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)(xing)實(shi)質(zhi)包(bao)(bao)塊,胰(yi)腺(xian)(xian)癌(ai)(ai)(ai)(ai),肝癌(ai)(ai)(ai)(ai)等(deng)(deng)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)治(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)(zhi)療(liao)(liao)(liao)(liao)(liao)(liao)(liao)(liao)。近幾年(nian),該技術(shu)(shu)(shu)(shu)(shu)在(zai)(zai)(zai)(zai)(zai)國(guo)(guo)內(nei)(nei)外(wai)推廣(guang)迅(xun)速(su),并(bing)越來越受患(huan)者(zhe)的(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)(de)歡(huan)迎。
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