在身體有(you)一些不適癥狀的(de)(de)時(shi)候,很多人會想(xiang)到(dao)用(yong)藥物來解決這些問題。每種藥物有(you)什么(me)作(zuo)用(yong),當然包(bao)裝盒上都(dou)有(you)標示(shi)出來。不過有(you)些時(shi)候,作(zuo)為(wei)不是專(zhuan)業的(de)(de)人員來說,多少還是會有(you)點(dian)疑(yi)惑。越鞠丸也是一種中成(cheng)藥,大多數人都(dou)不太(tai)清(qing)楚它的(de)(de)作(zuo)用(yong)是什么(me),以及(ji)和逍遙丸的(de)(de)區別有(you)哪些。接下來就(jiu)聽小編(bian)是怎(zen)么(me)講的(de)(de)吧。
1、和逍遙丸的區別
其(qi)實,越鞠丸(wan)(wan)和逍遙丸(wan)(wan)區別(bie)還(huan)是很容易(yi)看出(chu)來的。越鞠丸(wan)(wan)只有(you)五種成(cheng)分,其(qi)中包(bao)括(kuo)香附、六神曲乃至川芎和蒼術,當(dang)然了還(huan)添加了一些(xie)(xie)梔子(zi),主要(yao)適(shi)用于(yu)理氣解郁,在寬(kuan)中除滿方(fang)面的效果也不錯。而逍遙丸(wan)(wan)的成(cheng)分更(geng)多(duo)一些(xie)(xie),共(gong)有(you)八味(wei),其(qi)中有(you)柴胡、白芍乃至當(dang)歸(gui)等,除了能(neng)夠疏肝健脾之外(wai),還(huan)能(neng)用于(yu)調經養血,可(ke)以看出(chu)功效和作用也比較多(duo)。
因(yin)此大家在(zai)感覺(jue)到身(shen)體不(bu)(bu)適時,還(huan)請按藥品(pin)說明書或是(shi)(shi)在(zai)藥師的指導下購買和使(shi)用藥物(wu)(wu)。女(nv)性在(zai)月(yue)經期間若是(shi)(shi)感覺(jue)到胸悶脹痛或是(shi)(shi)情緒暴躁等,就可(ke)以(yi)服用逍(xiao)遙丸(wan)來醫治(zhi),效果還(huan)不(bu)(bu)錯。若平時胸悶氣短(duan),則可(ke)以(yi)適量(liang)的服用越鞠丸(wan)進行知(zhi)道了。當然(ran)了這兩種藥物(wu)(wu)的安全性都比較高,服藥之(zhi)后不(bu)(bu)會有不(bu)(bu)良反(fan)應及(ji)禁忌癥,不(bu)(bu)過(guo)一旦(dan)出現身(shen)體不(bu)(bu)適的現象就要立刻停藥了,對藥物(wu)(wu)過(guo)敏的話更要禁用。
2、副作用
《醫(yi)方集(ji)解》對越鞠丸(wan)的論(lun)述:此手足太陰(yin)手少陽(yang)藥也。吳鶴(he)皋曰:越鞠者,發越鞠郁(yu)(yu)之謂也。香附開氣郁(yu)(yu);蒼(cang)術燥(zao)濕郁(yu)(yu);撫芎調血郁(yu)(yu);梔子解火郁(yu)(yu);神曲消食郁(yu)(yu)。
越鞠丸的功用主(zhu)治是行氣(qi)(qi)解(jie)郁,氣(qi)(qi)、血、痰、火、濕、食等(deng)郁,胸膈痞(pi)悶(men),脘腹脹痛(tong),吞(tun)酸吐逆,飲(yin)食不化;六(liu)郁牙(ya)齒痛(tong),口瘡,或胸滿吐酸,飲(yin)食少思;婦人(ren)思想無窮,所(suo)欲(yu)不遂,帶脈(mo)不約,發(fa)為白淫。
可(ke)是越(yue)鞠丸副作用(yong)沒有明確,因(yin)而(er)越(yue)鞠丸安全性(xing)比較高(gao)。可(ke)是越(yue)鞠丸究(jiu)竟屬于中(zhong)成(cheng)藥(yao)(yao),因(yin)而(er)我(wo)們(men)要(yao)注意服用(yong)中(zhong)成(cheng)藥(yao)(yao)的患者朋友們(men)要(yao)注意"中(zhong)病即止",不(bu)可(ke)長時(shi)間服用(yong)。有些(xie)中(zhong)藥(yao)(yao)毒(du)性(xing)小,但長時(shi)間服用(yong),可(ke)積(ji)蓄(xu)中(zhong)毒(du)。
3、越鞠保和丸的作用
第一(yi),我(wo)們(men)的(de)胃出現問題時,可(ke)以使(shi)用越鞠保和丸,但是(shi)(shi)也要(yao)看具體的(de)情(qing)(qing)況,這一(yi)藥物的(de)作用表現為解除肝氣(qi)瘀(yu)滯(zhi),疏導氣(qi)機,調理情(qing)(qing)志抑郁導致的(de)肝氣(qi)瘀(yu)滯(zhi),增強食欲,是(shi)(shi)我(wo)們(men)有(you)吃飯的(de)胃口的(de)功效(xiao)。
第二,緩解以(yi)便(bian)(bian)秘為主要癥狀,排(pai)便(bian)(bian)次(ci)數減少,或排(pai)便(bian)(bian)不舒暢、困難,糞便(bian)(bian)干(gan)結(jie)且量少,而(er)產生的(de)胃(wei)痛(tong),這是(shi)越鞠保(bao)和丸的(de)第二個作(zuo)用。
第三,緩解(jie)患者的肚子脹氣(qi)、不消(xiao)化(hua)、食(shi)量減少而引起(qi)的消(xiao)化(hua)不良的癥(zheng)狀。停藥后癥(zheng)狀會得(de)到緩解(jie),多(duo)數并不需(xu)要進(jin)行(xing)特殊治療。
4、用法用量
越鞠丸別名也叫(jiao)做“芎術丸”,是一種(zhong)主要治(zhi)療(liao)(liao)身體各個部位器官積郁(yu)(yu)的一張方劑,可以(yi)治(zhi)療(liao)(liao)因(yin)氣郁(yu)(yu)、痰(tan)郁(yu)(yu)、火郁(yu)(yu)、血郁(yu)(yu)、食郁(yu)(yu)、濕郁(yu)(yu)而(er)導致的一系列癥(zheng)狀,包括飲食不良、嘔(ou)吐、心情煩悶、消(xiao)痰(tan)行氣等。
越(yue)鞠(ju)丸(wan)可(ke)以調理患者(zhe)的(de)(de)精氣神(shen)(shen)兒,其中包含的(de)(de)成(cheng)(cheng)分有(you)由炒(chao)蒼(cang)術、醋炒(chao)香(xiang)附、川芎、炒(chao)神(shen)(shen)曲、黑山梔等(deng)五味藥研成(cheng)(cheng)比較細的(de)(de)狀態,然后(hou)加水,做(zuo)成(cheng)(cheng)藥丸(wan),大小跟綠豆(dou)差不(bu)多(duo)(duo)(duo)。患者(zhe)每(mei)次(ci)可(ke)以服用15克,每(mei)天兩次(ci),堅持下來就可(ke)以達到改良的(de)(de)效果(guo)。越(yue)鞠(ju)丸(wan)已經(jing)有(you)很多(duo)(duo)(duo)年的(de)(de)歷史了,藥效也非常好,但是患者(zhe)也需要(yao)注意,在(zai)(zai)服藥期間一(yi)定(ding)要(yao)忌發(fa)怒,在(zai)(zai)飲(yin)食(shi)(shi)上要(yao)多(duo)(duo)(duo)吃一(yi)些(xie)容易消(xiao)化(hua)的(de)(de)食(shi)(shi)物。孕(yun)婦要(yao)禁止使用越(yue)鞠(ju)丸(wan)。如果(guo)在(zai)(zai)服用了幾天之后(hou)發(fa)現(xian)效果(guo)并沒(mei)有(you)改善,一(yi)定(ding)要(yao)停止使用。
目錄1拼音2英文(wen)參考(kao)3概述(shu)4《丹溪心(xin)(xin)法(fa)》卷三方(fang)(fang)之越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan) 4.1方(fang)(fang)名(ming)4.2越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)的(de)(de)(de)(de)別(bie)名(ming)4.3組(zu)成4.4功(gong)效與(yu)主(zhu)治(zhi)4.5越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)的(de)(de)(de)(de)用(yong)(yong)(yong)法(fa)用(yong)(yong)(yong)量(liang)(liang)4.6方(fang)(fang)解4.7臨床運用(yong)(yong)(yong) 4.7.1加減法(fa)4.7.2使(shi)用(yong)(yong)(yong)禁忌 4.8現代適(shi)應證 4.8.1胃(wei)及(ji)十二(er)指腸潰(kui)瘍4.8.2慢性(xing)肝炎(yan)4.8.3慢性(xing)胃(wei)炎(yan)4.8.4肋間神經痛(tong)4.8.5胃(wei)腸神經官能癥4.8.6膽石癥、膽囊(nang)炎(yan)4.8.7婦女月經不調4.8.8痛(tong)經 4.9越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)的(de)(de)(de)(de)藥理作(zuo)用(yong)(yong)(yong) 4.9.1抗病(bing)原微(wei)生物作(zuo)用(yong)(yong)(yong)4.9.2對消化(hua)系統功(gong)能的(de)(de)(de)(de)影(ying)(ying)響4.9.3對神經、內分泌及(ji)免疫功(gong)能的(de)(de)(de)(de)影(ying)(ying)響4.9.4對心(xin)(xin)臟、血管(guan)、血液(ye)流變學的(de)(de)(de)(de)影(ying)(ying)響4.9.5對子宮的(de)(de)(de)(de)作(zuo)用(yong)(yong)(yong)4.9.6抗炎(yan)、抗氧化(hua)作(zuo)用(yong)(yong)(yong) 4.10各(ge)家論(lun)述(shu)4.11歌(ge)訣4.12出處(chu) 5《口(kou)齒(chi)類要(yao)》方(fang)(fang)之越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan) 5.1方(fang)(fang)名(ming)5.2組(zu)成5.3主(zhu)治(zhi)5.4越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)的(de)(de)(de)(de)用(yong)(yong)(yong)法(fa)用(yong)(yong)(yong)量(liang)(liang)5.5制(zhi)備(bei)(bei)方(fang)(fang)法(fa)5.6出處(chu) 6《女科(ke)切要(yao)》卷二(er)方(fang)(fang)之越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan) 6.1方(fang)(fang)名(ming)6.2組(zu)成6.3主(zhu)治(zhi)6.4出處(chu) 7越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)的(de)(de)(de)(de)藥典標(biao)準 7.1品(pin)(pin)(pin)(pin)名(ming)7.2處(chu)方(fang)(fang)7.3制(zhi)法(fa)7.4性(xing)狀(zhuang)7.5鑒別(bie)7.6檢查7.7含量(liang)(liang)測(ce)定 7.7.1色(se)譜條(tiao)件與(yu)系統適(shi)用(yong)(yong)(yong)性(xing)試(shi)驗7.7.2對照品(pin)(pin)(pin)(pin)溶液(ye)的(de)(de)(de)(de)制(zhi)備(bei)(bei)7.7.3供(gong)試(shi)品(pin)(pin)(pin)(pin)溶液(ye)的(de)(de)(de)(de)制(zhi)備(bei)(bei)7.7.4測(ce)定法(fa) 7.8功(gong)能與(yu)主(zhu)治(zhi)7.9用(yong)(yong)(yong)法(fa)與(yu)用(yong)(yong)(yong)量(liang)(liang)7.10貯藏7.11版本 8越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)藥品(pin)(pin)(pin)(pin)說明(ming)書(shu) 8.1藥品(pin)(pin)(pin)(pin)名(ming)稱8.2藥品(pin)(pin)(pin)(pin)漢語拼音8.3性(xing)狀(zhuang)8.4越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)的(de)(de)(de)(de)主(zhu)要(yao)成份8.5越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)的(de)(de)(de)(de)功(gong)能主(zhu)治(zhi)8.6越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)的(de)(de)(de)(de)用(yong)(yong)(yong)法(fa)用(yong)(yong)(yong)量(liang)(liang)8.7注(zhu)意事項8.8越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)與(yu)其(qi)它藥物的(de)(de)(de)(de)相互作(zuo)用(yong)(yong)(yong)8.9備(bei)(bei)注(zhu) 9參考(kao)資料附:1古籍中(zhong)的(de)(de)(de)(de)越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)*越(yue)(yue)(yue)(yue)(yue)鞠(ju)(ju)(ju)丸(wan)(wan)(wan)相關(guan)藥品(pin)(pin)(pin)(pin)說明(ming)書(shu)其(qi)它版本 1拼音 yuè jū wán
2英(ying)文參(can)考 yueju pills [中醫(yi)(yi)藥學(xue)名(ming)詞審定委員會(hui).中醫(yi)(yi)藥學(xue)名(ming)詞(2004)]
yueju wan [中醫(yi)(yi)藥(yao)學(xue)名詞審(shen)定委(wei)員會.中醫(yi)(yi)藥(yao)學(xue)名詞(2004)]
3概述 越(yue)鞠(ju)丸同(tong)名方劑約有三首,其中(zhong)《丹溪心法(fa)》卷(juan)三記載者為(wei)常用方,其組成為(wei)蒼術、香附(fu)、川芎、神曲、梔子(zi)各(ge)等份(fen),具有行氣解郁(yu)之功效(xiao)。主(zhu)治氣、血、痰(tan)、火、濕、食六種郁(yu)證,但(dan)以(yi)治療氣郁(yu)為(wei)主(zhu),為(wei)治療郁(yu)證的代表方劑。現代常用于胃(wei)腸(chang)神經官(guan)能癥(zheng)、胃(wei)腸(chang)功能紊亂、胃(wei)及(ji)十(shi)二指腸(chang)潰瘍、慢性胃(wei)炎、消化不良、膽石(shi)癥(zheng)、膽囊炎、肝炎、肋間神經痛、精神抑郁(yu)癥(zheng)、痛經,以(yi)及(ji)偏(pian)頭(tou)痛、低(di)血鉀等有六郁(yu)見(jian)癥(zheng)者。
《中華(hua)人(ren)民共和國藥(yao)(yao)典》(2010年版)記載(zai)有(you)越鞠丸成藥(yao)(yao)藥(yao)(yao)典標(biao)準。
4《丹溪心(xin)法》卷三方之(zhi)越(yue)鞠丸 該(gai)方劑(ji)(ji)具有一(yi)定的(de)抗病(bing)原微生(sheng)物(wu)作(zuo)用(yong),對胃(wei)(wei)腸(chang)道既能促進消化功能又能抗潰瘍(yang);對中(zhong)樞神(shen)經(jing)及(ji)內分泌功能有一(yi)定調(diao)控作(zuo)用(yong),君藥(yao)(yao)和臣藥(yao)(yao)有一(yi)定雌(ci)激(ji)素(su)樣作(zuo)用(yong),故可以(yi)用(yong)來治(zhi)(zhi)療(liao)慢性(xing)胃(wei)(wei)炎、胃(wei)(wei)及(ji)十二指腸(chang)潰瘍(yang)、胃(wei)(wei)神(shen)經(jing)官能癥等疾病(bing),但如(ru)果是幽門螺(luo)旋桿(gan)菌(jun)感(gan)染(ran)所致,最好(hao)(hao)配(pei)合(he)(he)現代(dai)醫學(xue)療(liao)法:抗幽門螺(luo)旋桿(gan)菌(jun)藥(yao)(yao)+抗酸藥(yao)(yao)+質(zhi)子(zi)泵抑(yi)制劑(ji)(ji)+胃(wei)(wei)黏膜保(bao)護劑(ji)(ji)等。該(gai)方劑(ji)(ji)只有梔(zhi)子(zi)對肝(gan)、膽疾病(bing)有治(zhi)(zhi)療(liao)作(zuo)用(yong),故對急(ji)、慢性(xing)肝(gan)炎最好(hao)(hao)再加味其他(ta)有關治(zhi)(zhi)療(liao)肝(gan)炎的(de)中(zhong)草(cao)藥(yao)(yao)或配(pei)合(he)(he)西藥(yao)(yao)治(zhi)(zhi)療(liao)。對膽系感(gan)染(ran)疾病(bing)配(pei)合(he)(he)抗生(sheng)素(su)及(ji)外科治(zhi)(zhi)療(liao)。由于(yu)有兩味藥(yao)(yao)具有雌(ci)激(ji)素(su)樣作(zuo)用(yong),可能對痛經(jing)、月經(jing)不調(diao)有治(zhi)(zhi)療(liao)作(zuo)用(yong)。[1]
越曲丸(《松崖醫徑》卷下)。
蒼術、香附、川芎、神曲、梔(zhi)子(zi)各等份[3]
香附(fu)6g、川芎6g、蒼術(shu)6g、神曲6g、梔子6g。[4]
越(yue)鞠丸功(gong)能行(xing)氣(qi)解(jie)郁[5]。治(zhi)氣(qi)、血(xue)、痰、火、濕、食(shi)諸郁,胸膈痞(pi)悶(men),吞酸(suan)嘔吐(tu),飲食(shi)不消(xiao)等癥[5]。
上共(gong)為細末,水(shui)泛為丸(wan),每服(fu)6~9g,每日2次。或(huo)作(zuo)湯劑,水(shui)煎服(fu)。[3]
越(yue)鞠丸方中(zhong)以(yi)香附行氣(qi)(qi)解(jie)郁(yu)(yu)(yu),以(yi)治氣(qi)(qi)郁(yu)(yu)(yu),為(wei)(wei)君藥。川芎為(wei)(wei)血(xue)中(zhong)之(zhi)氣(qi)(qi)藥,既可活血(xue)祛瘀,以(yi)治血(xue)郁(yu)(yu)(yu),又可助香附行氣(qi)(qi)解(jie)郁(yu)(yu)(yu)之(zhi)功;梔子(zi)清熱(re)瀉火(huo)(huo),以(yi)治火(huo)(huo)郁(yu)(yu)(yu);蒼術燥濕運脾,以(yi)治濕郁(yu)(yu)(yu);神曲消(xiao)食導(dao)滯,以(yi)治食郁(yu)(yu)(yu),共為(wei)(wei)臣(chen)佐(zuo)藥。痰郁(yu)(yu)(yu)多(duo)由脾濕所生,亦(yi)與(yu)氣(qi)(qi)、火(huo)(huo)、食有關,氣(qi)(qi)機流暢,諸郁(yu)(yu)(yu)得解(jie),則痰郁(yu)(yu)(yu)亦(yi)隨之(zhi)而消(xiao),此亦(yi)治病(bing)求(qiu)本之(zhi)意。[4]
方中香附行氣(qi)解(jie)郁(yu),以(yi)(yi)(yi)治(zhi)(zhi)氣(qi)郁(yu);蒼術燥濕健脾,以(yi)(yi)(yi)治(zhi)(zhi)濕郁(yu);川芎行氣(qi)活血(xue),以(yi)(yi)(yi)治(zhi)(zhi)血(xue)郁(yu);神曲消(xiao)食和胃,以(yi)(yi)(yi)治(zhi)(zhi)食郁(yu);梔子清熱除煩,以(yi)(yi)(yi)治(zhi)(zhi)火郁(yu)[5]。本方著(zhu)重于行氣(qi)解(jie)郁(yu),氣(qi)行則(ze)血(xue)行,氣(qi)暢(chang)則(ze)痰(tan)、火、濕、食諸郁(yu)自(zi)解(jie),痛(tong)悶可除[5]
4.7.1加減法(fa) 若氣(qi)郁(yu)(yu)偏(pian)(pian)(pian)(pian)重(zhong)(zhong),可(ke)重(zhong)(zhong)用(yong)(yong)(yong)香附,酌(zhuo)情加木香、枳殼、厚樸等以增強(qiang)其行(xing)氣(qi)解郁(yu)(yu)之力(li);若血郁(yu)(yu)偏(pian)(pian)(pian)(pian)重(zhong)(zhong),重(zhong)(zhong)用(yong)(yong)(yong)川芎,酌(zhuo)加桃仁、赤(chi)芍、紅花等以增強(qiang)活血祛瘀之力(li):若濕(shi)郁(yu)(yu)偏(pian)(pian)(pian)(pian)重(zhong)(zhong),重(zhong)(zhong)用(yong)(yong)(yong)蒼術,酌(zhuo)加茯苓(ling)、澤瀉以利濕(shi);若食郁(yu)(yu)偏(pian)(pian)(pian)(pian)重(zhong)(zhong),重(zhong)(zhong)用(yong)(yong)(yong)神曲,酌(zhuo)加山(shan)楂、麥芽以消食化(hua)滯(zhi);火郁(yu)(yu)偏(pian)(pian)(pian)(pian)重(zhong)(zhong),重(zhong)(zhong)用(yong)(yong)(yong)山(shan)梔,酌(zhuo)加黃(huang)芩、黃(huang)連以清(qing)熱(re)瀉火;若痰(tan)郁(yu)(yu)偏(pian)(pian)(pian)(pian)重(zhong)(zhong),酌(zhuo)加半(ban)夏、瓜蔞以化(hua)痰(tan)。[3]
4.7.2使用禁忌 越鞠丸所治諸郁均屬實證,若為(wei)虛證引起(qi)的(de)郁滯,則宜配伍補(bu)益藥,不(bu)可單獨使用[3]。
4.8.1胃(wei)(wei)(wei)及(ji)(ji)十二指(zhi)腸潰(kui)瘍(yang)(yang)(yang) 胃(wei)(wei)(wei)潰(kui)瘍(yang)(yang)(yang)及(ji)(ji)十二指(zhi)腸潰(kui)瘍(yang)(yang)(yang)統稱為(wei)消化性(xing)潰(kui)瘍(yang)(yang)(yang),最常見(jian)的原因(yin)是(shi)幽門螺(luo)旋桿菌感染及(ji)(ji)服(fu)用非甾體類抗(kang)炎藥(yao),二者(zhe)均會導致胃(wei)(wei)(wei)、十二指(zhi)腸黏(nian)膜屏障破(po)壞(huai),在正常黏(nian)膜損害(hai)、防御和(he)修復過程中,胃(wei)(wei)(wei)酸及(ji)(ji)胃(wei)(wei)(wei)蛋白(bai)酶(mei)分泌(mi)增加,是(shi)損害(hai)發生(sheng)的直接因(yin)素,繼而(er)發生(sheng)潰(kui)瘍(yang)(yang)(yang),其主要病理改變是(shi)十二指(zhi)腸球部(bu)、胃(wei)(wei)(wei)角或胃(wei)(wei)(wei)小彎處出(chu)現圓(yuan)形或橢圓(yuan)形潰(kui)瘍(yang)(yang)(yang),邊緣光(guang)整、底部(bu)潔凈(jing),由肉芽(ya)組織構成,上(shang)面(mian)覆蓋灰(hui)白(bai)色或灰(hui)黃色纖維滲出(chu)物。活動性(xing)潰(kui)瘍(yang)(yang)(yang)周(zhou)圍黏(nian)膜常有炎性(xing)水腫,潰(kui)瘍(yang)(yang)(yang)淺者(zhe)累及(ji)(ji)黏(nian)膜肌層(ceng),深者(zhe)可達漿膜層(ceng),血管(guan)潰(kui)破(po)時(shi)引起(qi)出(chu)血,穿破(po)漿膜層(ceng)引起(qi)穿孔。臨床上(shang)主要表現為(wei)腹鈍(dun)痛(tong)、灼痛(tong)、脹痛(tong)等,尤以空腹時(shi)為(wei)著;周(zhou)期性(xing)發作,秋(qiu)冬季為(wei)多,發作具有節律性(xing),查體可見(jian)上(shang)腹部(bu)局部(bu)輕壓(ya)痛(tong)。[6]
4.8.2慢(man)(man)性(xing)(xing)(xing)肝炎(yan) 慢(man)(man)性(xing)(xing)(xing)肝炎(yan)是肝硬(ying)化最(zui)常見的原因(yin),慢(man)(man)性(xing)(xing)(xing)肝炎(yan)多由乙(yi)、丙(bing)、丁3型肝炎(yan)急(ji)性(xing)(xing)(xing)期(qi)轉變而來,凡病(bing)期(qi)超過半(ban)年,或(huo)乙(yi)、丙(bing)、丁3型肝炎(yan)或(huo)HBsAg攜(xie)帶者(zhe)再次出現肝炎(yan)癥狀體(ti)征、肝功能異常者(zhe),或(huo)雖(sui)病(bing)史不明(ming),但肝病(bing)理組織(zhi)學或(huo)癥狀、體(ti)征、B超檢查符合慢(man)(man)性(xing)(xing)(xing)肝炎(yan)均可(ke)定為(wei)慢(man)(man)性(xing)(xing)(xing)肝炎(yan)。由于肝臟腫大,匯管區出現不同程度炎(yan)癥、肝小葉(xie)壞死,并出現不同程度的纖維化、膽汁排泄(xie)障(zhang)礙以及(ji)腸(chang)道瘀血,可(ke)致消化道功能障(zhang)礙及(ji)胸脅脹滿等癥狀。[6]
4.8.3慢(man)(man)性(xing)(xing)胃(wei)(wei)(wei)(wei)炎 慢(man)(man)性(xing)(xing)胃(wei)(wei)(wei)(wei)炎又分(fen)慢(man)(man)性(xing)(xing)淺表(biao)(biao)性(xing)(xing)胃(wei)(wei)(wei)(wei)炎及慢(man)(man)性(xing)(xing)萎縮性(xing)(xing)胃(wei)(wei)(wei)(wei)炎,其發病原因有3:①幽門螺旋桿菌(jun)(jun)感染(ran)是(shi)主(zhu)要(yao)原因,該(gai)菌(jun)(jun)有鞭毛,對胃(wei)(wei)(wei)(wei)黏膜(mo)穿過(guo)能力(li)強,分(fen)泌(mi)空(kong)泡毒素A,引起(qi)強烈炎癥反應;該(gai)菌(jun)(jun)細(xi)胞壁(bi)(bi)作為抗原誘導免疫(yi)反應,從而共同引起(qi)胃(wei)(wei)(wei)(wei)黏膜(mo)慢(man)(man)性(xing)(xing)炎癥。②飲(yin)(yin)食和環(huan)境因素如高鹽飲(yin)(yin)食及缺乏水果蔬菜等(deng)增加了胃(wei)(wei)(wei)(wei)炎的易感性(xing)(xing)。③自身免疫(yi),患者血中存在壁(bi)(bi)細(xi)胞抗體,攻擊壁(bi)(bi)細(xi)胞,導致胃(wei)(wei)(wei)(wei)黏膜(mo)病變(bian)。④其他因素如含膽汁(zhi)及胰液的十二(er)指腸液反流入(ru)胃(wei)(wei)(wei)(wei)、酗(xu)酒、某些(xie)食物(wu) *** 等(deng)或單獨或與幽門螺旋桿菌(jun)(jun)協同導致胃(wei)(wei)(wei)(wei)黏膜(mo)病變(bian)。慢(man)(man)性(xing)(xing)胃(wei)(wei)(wei)(wei)炎主(zhu)要(yao)病理改變(bian)是(shi)炎癥、萎縮和腸化生。臨(lin)床主(zhu)要(yao)表(biao)(biao)現為上腹(fu)痛、腹(fu)脹等(deng)消(xiao)化道癥狀。[6]
4.8.4肋(lei)間神經(jing)痛 肋(lei)間神經(jing)痛多數由細菌、病毒感(gan)染,創傷,肋(lei)間神經(jing)腫(zhong)瘤(liu)或(huo)神經(jing)根、脊髓部位感(gan)染或(huo)腫(zhong)瘤(liu)壓迫所(suo)致,臨床表現為胸部之沿(yan)神經(jing)分(fen)布的刺(ci)痛或(huo)灼(zhuo)痛。[6]
4.8.5胃腸(chang)神(shen)經(jing)官能癥 胃腸(chang)神(shen)經(jing)官能癥并(bing)不(bu)是(shi)(shi)胃腸(chang)的器質性疾病(bing),而是(shi)(shi)由于患者神(shen)經(jing)精神(shen)緊張、焦慮、恐懼、疑病(bing)或癔癥等(deng)所致(zhi),其臨床表(biao)現為腹(fu)痛、腹(fu)瀉,而每次發病(bing)均(jun)與精神(shen)因素密切相關(guan)。[6]
4.8.6膽(dan)(dan)(dan)(dan)(dan)石(shi)癥(zheng)(zheng)、膽(dan)(dan)(dan)(dan)(dan)囊炎(yan)(yan) 急(ji)(ji)性(xing)膽(dan)(dan)(dan)(dan)(dan)囊炎(yan)(yan)是(shi)膽(dan)(dan)(dan)(dan)(dan)囊發(fa)生的急(ji)(ji)性(xing)化學性(xing)或(huo)細(xi)菌性(xing)炎(yan)(yan)癥(zheng)(zheng)。膽(dan)(dan)(dan)(dan)(dan)道(dao)感染(ran)與膽(dan)(dan)(dan)(dan)(dan)石(shi)癥(zheng)(zheng)互為因果關系,膽(dan)(dan)(dan)(dan)(dan)石(shi)癥(zheng)(zheng)可引起膽(dan)(dan)(dan)(dan)(dan)道(dao)梗阻,導致(zhi)膽(dan)(dan)(dan)(dan)(dan)汁(zhi)瘀滯(zhi),細(xi)菌繁殖而(er)致(zhi)膽(dan)(dan)(dan)(dan)(dan)道(dao)感染(ran),膽(dan)(dan)(dan)(dan)(dan)道(dao)感染(ran)的反(fan)復發(fa)作又是(shi)膽(dan)(dan)(dan)(dan)(dan)石(shi)形成(cheng)的重(zhong)要因素。其主要病理變化是(shi)膽(dan)(dan)(dan)(dan)(dan)囊管梗阻,膽(dan)(dan)(dan)(dan)(dan)囊腫大(da),壓力升高,黏(nian)膜(mo)充(chong)血水腫、滲出增加,進一步(bu)發(fa)展為化膿(nong)(nong)性(xing)膽(dan)(dan)(dan)(dan)(dan)囊炎(yan)(yan)和壞疽性(xing)膽(dan)(dan)(dan)(dan)(dan)囊炎(yan)(yan);如果反(fan)復發(fa)作,膽(dan)(dan)(dan)(dan)(dan)囊中膿(nong)(nong)液進入(ru)膽(dan)(dan)(dan)(dan)(dan)管和胰腺管可引起膽(dan)(dan)(dan)(dan)(dan)囊炎(yan)(yan)或(huo)胰腺炎(yan)(yan),也可引起膽(dan)(dan)(dan)(dan)(dan)囊穿(chuan)孔,或(huo)穿(chuan)破到十二(er)指腸等器官形成(cheng)膽(dan)(dan)(dan)(dan)(dan)囊胃腸道(dao)內瘺。[6]
4.8.7婦女月(yue)經不(bu)(bu)(bu)(bu)調(diao)(diao)(diao) 婦女月(yue)經不(bu)(bu)(bu)(bu)調(diao)(diao)(diao)包括若干(gan)疾病,但(dan)主(zhu)(zhu)要(yao)(yao)是(shi)指功(gong)能失調(diao)(diao)(diao)性(xing)子(zi)(zi)(zi)宮出(chu)血(xue),包括:①無排卵(luan)(luan)性(xing)功(gong)能失調(diao)(diao)(diao)性(xing)子(zi)(zi)(zi)宮出(chu)血(xue),是(shi)由于(yu)機(ji)體(ti)(ti)受內(nei)部(bu)或(huo)(huo)(huo)外部(bu)因(yin)素如精(jing)神緊(jin)張、代(dai)謝紊(wen)(wen)亂、氣候驟變等(deng)影響,通過大腦皮層和中(zhong)樞神經系(xi)統引(yin)起的下(xia)丘(qiu)腦-垂體(ti)(ti)-卵(luan)(luan)巢(chao)軸功(gong)能調(diao)(diao)(diao)節(jie)或(huo)(huo)(huo)靶細(xi)胞(bao)效(xiao)應異(yi)(yi)常而(er)致(zhi)月(yue)經失調(diao)(diao)(diao)。子(zi)(zi)(zi)宮內(nei)膜(mo)(mo)主(zhu)(zhu)要(yao)(yao)表現(xian)為(wei):組(zu)織脆(cui)性(xing)增(zeng)加,子(zi)(zi)(zi)宮內(nei)膜(mo)(mo)脫(tuo)落不(bu)(bu)(bu)(bu)完全(quan)至修復困難、凝(ning)血(xue)與纖(xian)溶(rong)異(yi)(yi)常,臨(lin)床(chuang)表現(xian)為(wei)月(yue)經周期紊(wen)(wen)亂,經期長短(duan)不(bu)(bu)(bu)(bu)一,經量不(bu)(bu)(bu)(bu)定(ding),甚至大量出(chu)血(xue)。②排卵(luan)(luan)性(xing)月(yue)經失調(diao)(diao)(diao),是(shi)由于(yu)月(yue)經周期中(zhong)有卵(luan)(luan)泡(pao)發育及(ji)排卵(luan)(luan),但(dan)黃(huang)體(ti)(ti)期孕(yun)激素分泌(mi)(mi)不(bu)(bu)(bu)(bu)足或(huo)(huo)(huo)黃(huang)體(ti)(ti)過早衰退,導(dao)(dao)致(zhi)子(zi)(zi)(zi)宮內(nei)膜(mo)(mo)分泌(mi)(mi)反應不(bu)(bu)(bu)(bu)良,主(zhu)(zhu)要(yao)(yao)病理是(shi)子(zi)(zi)(zi)宮內(nei)膜(mo)(mo)腺體(ti)(ti)呈(cheng)分泌(mi)(mi)不(bu)(bu)(bu)(bu)良,間質水腫不(bu)(bu)(bu)(bu)明顯或(huo)(huo)(huo)腺體(ti)(ti)與間質發育不(bu)(bu)(bu)(bu)同步(bu),臨(lin)床(chuang)主(zhu)(zhu)要(yao)(yao)表現(xian)為(wei)月(yue)經周期縮短(duan)。另一種是(shi)由于(yu)丘(qiu)腦-垂體(ti)(ti)-卵(luan)(luan)巢(chao)軸調(diao)(diao)(diao)節(jie)功(gong)能紊(wen)(wen)亂或(huo)(huo)(huo)溶(rong)黃(huang)體(ti)(ti)機(ji)制異(yi)(yi)常引(yin)起的黃(huang)體(ti)(ti)萎靡不(bu)(bu)(bu)(bu)全(quan),導(dao)(dao)致(zhi)子(zi)(zi)(zi)宮內(nei)膜(mo)(mo)不(bu)(bu)(bu)(bu)規則脫(tuo)落,臨(lin)床(chuang)主(zhu)(zhu)要(yao)(yao)表現(xian)為(wei)月(yue)經周期延(yan)長,經期可延(yan)長達9~10日,且出(chu)血(xue)量多。[6]
4.8.8痛(tong)(tong)經(jing)(jing) 痛(tong)(tong)經(jing)(jing)是(shi)指在(zai)經(jing)(jing)期(qi)或經(jing)(jing)期(qi)前后出現周期(qi)性(xing)(xing)的小腹疼(teng)痛(tong)(tong),或痛(tong)(tong)引(yin)腰骶,甚(shen)而(er)劇痛(tong)(tong)暈厥(jue)。這是(shi)一(yi)(yi)組(zu)綜合征,包括功能性(xing)(xing)(原(yuan)發性(xing)(xing))痛(tong)(tong)經(jing)(jing)。第一(yi)(yi)是(shi)生(sheng)殖器(qi)官無(wu)明顯器(qi)質(zhi)性(xing)(xing)病(bing)變;第二(er)是(shi)繼發性(xing)(xing)痛(tong)(tong)經(jing)(jing),多見于生(sheng)殖器(qi)官的某些(xie)器(qi)質(zhi)性(xing)(xing)病(bing)變,如盆腔子(zi)宮內(nei)膜異位癥、子(zi)宮腺肌(ji)(ji)病(bing)、慢性(xing)(xing)盆腔炎、婦科腫瘤、宮頸口(kou)粘連狹窄等(deng)。這里重點敘述原(yuan)發性(xing)(xing)痛(tong)(tong)經(jing)(jing)。痛(tong)(tong)經(jing)(jing)患者子(zi)宮內(nei)膜和血(xue)液中(zhong)PGF2α、PGE2含(han)量明顯升高(gao),二(er)者是(shi)花生(sheng)四烯酸脂肪酸的衍生(sheng)物,在(zai)月(yue)經(jing)(jing)周期(qi)中(zhong),分泌期(qi)子(zi)宮內(nei)膜PG濃度(du)較增生(sheng)期(qi)為高(gao),月(yue)經(jing)(jing)期(qi)由于溶酶體不(bu)穩(wen)定,釋放各種溶解酶而(er)破(po)壞細胞膜,使子(zi)宮內(nei)膜細胞溶解,釋放PGF2α、PGE2,二(er)者可使子(zi)宮平滑(hua)(hua)肌(ji)(ji)過(guo)強收(shou)縮,甚(shen)至痙(jing)攣性(xing)(xing)收(shou)縮而(er)出現痛(tong)(tong)經(jing)(jing);另(ling)外,痛(tong)(tong)經(jing)(jing)也與子(zi)宮平滑(hua)(hua)肌(ji)(ji)不(bu)協調(diao)收(shou)縮,造成(cheng)子(zi)宮供血(xue)不(bu)足,導致厭氧代謝物積貯, *** 疼(teng)痛(tong)(tong)神(shen)經(jing)(jing)原(yuan)有關;原(yuan)發性(xing)(xing)痛(tong)(tong)經(jing)(jing)還與受(shou)精神(shen)、神(shen)經(jing)(jing)因素影響,疼(teng)痛(tong)(tong)的主觀感受(shou),個體的痛(tong)(tong)閾有關。無(wu)排卵(luan)性(xing)(xing)子(zi)宮內(nei)膜因無(wu)孕酮(tong) *** ,所含(han)PG濃度(du)甚(shen)低,一(yi)(yi)般不(bu)發生(sheng)痛(tong)(tong)經(jing)(jing)。[6]
4.9.1抗病(bing)原微生(sheng)物(wu)作(zuo)用(yong) 君藥香(xiang)附揮發(fa)油對(dui)金黃(huang)色(se)葡(pu)萄(tao)球(qiu)(qiu)(qiu)菌(jun)(jun)(jun)、痢(li)疾桿菌(jun)(jun)(jun)、瘧原蟲有(you)(you)抑(yi)制(zhi)作(zuo)用(yong),其提取物(wu)對(dui)某些真菌(jun)(jun)(jun)有(you)(you)抑(yi)制(zhi)作(zuo)用(yong)。臣藥蒼術水(shui)煎劑(ji)對(dui)結(jie)核桿菌(jun)(jun)(jun)、大腸(chang)桿菌(jun)(jun)(jun)、枯草桿菌(jun)(jun)(jun)、銅(tong)綠假單(dan)胞桿菌(jun)(jun)(jun)、腮腺炎(yan)病(bing)毒(du)(du)、HIV、流感病(bing)毒(du)(du)、黃(huang)霉菌(jun)(jun)(jun)及(ji)(ji)(ji)支原體(ti)等具有(you)(you)殺滅作(zuo)用(yong)。川芎對(dui)大腸(chang)桿菌(jun)(jun)(jun)、痢(li)疾桿菌(jun)(jun)(jun)、變(bian)形桿菌(jun)(jun)(jun)、銅(tong)綠假單(dan)胞桿菌(jun)(jun)(jun)、傷寒桿菌(jun)(jun)(jun)及(ji)(ji)(ji)多(duo)種(zhong)皮膚(fu)真菌(jun)(jun)(jun)均有(you)(you)顯著的抑(yi)制(zhi)作(zuo)用(yong)。梔子水(shui)煎劑(ji)對(dui)金黃(huang)色(se)葡(pu)萄(tao)球(qiu)(qiu)(qiu)菌(jun)(jun)(jun)、腦膜炎(yan)雙球(qiu)(qiu)(qiu)菌(jun)(jun)(jun)、卡他桿菌(jun)(jun)(jun)、溶血(xue)性鏈球(qiu)(qiu)(qiu)菌(jun)(jun)(jun)及(ji)(ji)(ji)多(duo)種(zhong)皮膚(fu)真菌(jun)(jun)(jun)均有(you)(you)抑(yi)制(zhi)作(zuo)用(yong),對(dui)血(xue)吸蟲及(ji)(ji)(ji)鉤端螺旋體(ti)有(you)(you)抑(yi)殺作(zuo)用(yong),且可抑(yi)制(zhi)柯薩(sa)奇B3病(bing)毒(du)(du)的增殖(zhi)。
4.9.2對(dui)(dui)(dui)(dui)消化系統功能(neng)的(de)影響 君藥香附可(ke)(ke)抑(yi)制(zhi)腸(chang)管(guan)(guan)收(shou)縮(suo)(suo),使(shi)肌(ji)(ji)張(zhang)力下降(jiang)(jiang),收(shou)縮(suo)(suo)幅度(du)降(jiang)(jiang)低(di)。臣藥蒼(cang)術水煎劑能(neng)明(ming)顯(xian)促進(jin)肝蛋白合(he)成(cheng),對(dui)(dui)(dui)(dui)肝細胞(bao)損(sun)害(hai)(hai)有(you)(you)(you)(you)明(ming)顯(xian)的(de)預防(fang)作(zuo)(zuo)用(yong),蒼(cang)術酮對(dui)(dui)(dui)(dui)叔丁(ding)基過氧化物誘(you)導的(de)DNA損(sun)害(hai)(hai)及(ji)肝細胞(bao)毒(du)性(xing)(xing)有(you)(you)(you)(you)抑(yi)制(zhi)作(zuo)(zuo)用(yong);能(neng)顯(xian)著抑(yi)制(zhi)胃(wei)液分(fen)泌,對(dui)(dui)(dui)(dui)多種實(shi)驗(yan)性(xing)(xing)胃(wei)潰瘍(yang)的(de)形(xing)成(cheng)有(you)(you)(you)(you)抑(yi)制(zhi)作(zuo)(zuo)用(yong);對(dui)(dui)(dui)(dui)胃(wei)腸(chang)運動有(you)(you)(you)(you)調(diao)節(jie)作(zuo)(zuo)用(yong),其(qi)丙酮提(ti)(ti)取物能(neng)明(ming)顯(xian)促進(jin)胃(wei)腸(chang)運動,其(qi)水溶液則對(dui)(dui)(dui)(dui)十二指腸(chang)平滑(hua)肌(ji)(ji)收(shou)縮(suo)(suo)有(you)(you)(you)(you)明(ming)顯(xian)抑(yi)制(zhi)作(zuo)(zuo)用(yong),對(dui)(dui)(dui)(dui)抗乙(yi)酰膽(dan)堿引起(qi)的(de)平滑(hua)肌(ji)(ji)收(shou)縮(suo)(suo)作(zuo)(zuo)用(yong),而對(dui)(dui)(dui)(dui)弛張(zhang)后(hou)的(de)胃(wei)腸(chang)平滑(hua)肌(ji)(ji)有(you)(you)(you)(you)輕(qing)微增(zeng)強收(shou)縮(suo)(suo)作(zuo)(zuo)用(yong);蒼(cang)術含有(you)(you)(you)(you)大量維(wei)(wei)生(sheng)素(su)A,并(bing)(bing)能(neng)增(zeng)加胃(wei)黏膜(mo)(mo)(mo)(mo)血流量,其(qi)所含氨(an)基己糖對(dui)(dui)(dui)(dui)胃(wei)黏膜(mo)(mo)(mo)(mo)有(you)(you)(you)(you)直接保(bao)護作(zuo)(zuo)用(yong),對(dui)(dui)(dui)(dui)胃(wei)腸(chang)黏膜(mo)(mo)(mo)(mo)維(wei)(wei)持(chi)正常(chang)結構及(ji)修復起(qi)到(dao)重(zhong)要(yao)作(zuo)(zuo)用(yong)。川芎能(neng)抑(yi)制(zhi)小腸(chang)收(shou)縮(suo)(suo),同時含有(you)(you)(you)(you)維(wei)(wei)生(sheng)素(su)A,對(dui)(dui)(dui)(dui)胃(wei)腸(chang)黏膜(mo)(mo)(mo)(mo)有(you)(you)(you)(you)修復維(wei)(wei)持(chi)完整的(de)作(zuo)(zuo)用(yong)。神曲含有(you)(you)(you)(you)酵(jiao)母菌、酶類、維(wei)(wei)生(sheng)素(su)B復合(he)體,有(you)(you)(you)(you)促進(jin)消化、增(zeng)進(jin)食(shi)欲、改(gai)善腸(chang)道(dao)菌群失調(diao)的(de)作(zuo)(zuo)用(yong)。梔(zhi)子(zi)對(dui)(dui)(dui)(dui)肝損(sun)傷(shang)有(you)(you)(you)(you)保(bao)護作(zuo)(zuo)用(yong),其(qi)正丁(ding)醇提(ti)(ti)取物對(dui)(dui)(dui)(dui)肝組(zu)織壞死、膽(dan)管(guan)(guan)周(zhou)圍炎和片狀壞死等病(bing)理變化有(you)(you)(you)(you)明(ming)顯(xian)保(bao)護作(zuo)(zuo)用(yong);并(bing)(bing)可(ke)(ke)降(jiang)(jiang)低(di)異常(chang)升(sheng)高的(de)ALT、AST及(ji)膽(dan)紅素(su),可(ke)(ke)促進(jin)膽(dan)囊收(shou)縮(suo)(suo)及(ji)膽(dan)汁排泌;其(qi)水提(ti)(ti)取物可(ke)(ke)抑(yi)制(zhi)胃(wei)酸分(fen)泌,對(dui)(dui)(dui)(dui)動物有(you)(you)(you)(you)顯(xian)著的(de)瀉下作(zuo)(zuo)用(yong);梔(zhi)子(zi)乙(yi)醇提(ti)(ti)取物低(di)濃(nong)度(du)對(dui)(dui)(dui)(dui)腸(chang)管(guan)(guan)有(you)(you)(you)(you)興(xing)奮作(zuo)(zuo)用(yong),高濃(nong)度(du)則有(you)(you)(you)(you)抑(yi)制(zhi)作(zuo)(zuo)用(yong);梔(zhi)子(zi)可(ke)(ke)促進(jin)胰(yi)腺分(fen)泌,降(jiang)(jiang)低(di)胰(yi)酶活(huo)性(xing)(xing),對(dui)(dui)(dui)(dui)胰(yi)腺細胞(bao)膜(mo)(mo)(mo)(mo)線粒體膜(mo)(mo)(mo)(mo)、溶酶體膜(mo)(mo)(mo)(mo)均有(you)(you)(you)(you)穩定作(zuo)(zuo)用(yong),能(neng)使(shi)胰(yi)腺細胞(bao)結構、功能(neng)趨于(yu)正常(chang)。
4.9.3對(dui)(dui)(dui)(dui)(dui)神(shen)經(jing)(jing)、內(nei)(nei)分泌及(ji)免(mian)疫(yi)功(gong)能(neng)(neng)的(de)(de)(de)影響 君(jun)藥(yao)香(xiang)(xiang)附對(dui)(dui)(dui)(dui)(dui)中(zhong)(zhong)(zhong)樞(shu)神(shen)經(jing)(jing)系(xi)統(tong)有(you)(you)(you)(you)安定(ding)作(zuo)用(yong)(yong)(yong)(yong),同(tong)時(shi)能(neng)(neng)提高(gao)動(dong)物的(de)(de)(de)痛(tong)閾值,具有(you)(you)(you)(you)鎮(zhen)(zhen)(zhen)靜(jing)、鎮(zhen)(zhen)(zhen)痛(tong)作(zuo)用(yong)(yong)(yong)(yong);香(xiang)(xiang)附醇提取物具有(you)(you)(you)(you)解(jie)熱(re)(re)作(zuo)用(yong)(yong)(yong)(yong),效價(jia)是(shi)水楊(yang)酸(suan)的(de)(de)(de)6倍(bei);香(xiang)(xiang)附揮發油有(you)(you)(you)(you)雌激素(su)樣作(zuo)用(yong)(yong)(yong)(yong)。臣藥(yao)蒼(cang)術(shu)對(dui)(dui)(dui)(dui)(dui)中(zhong)(zhong)(zhong)樞(shu)神(shen)經(jing)(jing)系(xi)統(tong)有(you)(you)(you)(you)鎮(zhen)(zhen)(zhen)靜(jing)作(zuo)用(yong)(yong)(yong)(yong),大劑(ji)(ji)量(liang)呈(cheng)抑(yi)(yi)制(zhi)作(zuo)用(yong)(yong)(yong)(yong),最終可導致呼(hu)吸(xi)(xi)麻痹;其煎劑(ji)(ji)有(you)(you)(you)(you)降血(xue)(xue)(xue)(xue)(xue)(xue)糖作(zuo)用(yong)(yong)(yong)(yong),同(tong)時(shi)使(shi)(shi)脊(ji)髓反(fan)射(she)亢進,大劑(ji)(ji)量(liang)則呈(cheng)抑(yi)(yi)制(zhi)作(zuo)用(yong)(yong)(yong)(yong);蒼(cang)術(shu)所(suo)含(han)β桉葉醇對(dui)(dui)(dui)(dui)(dui)煙堿(N)受體(ti)有(you)(you)(you)(you)阻斷作(zuo)用(yong)(yong)(yong)(yong),可降低(di)肌肉緊(jin)張性。川芎(xiong)嗪可透過血(xue)(xue)(xue)(xue)(xue)(xue)腦(nao)屏障,腦(nao)干中(zhong)(zhong)(zhong)的(de)(de)(de)含(han)量(liang)約為大腦(nao)的(de)(de)(de)4倍(bei);擴張腦(nao)血(xue)(xue)(xue)(xue)(xue)(xue)管,增(zeng)加(jia)腦(nao)血(xue)(xue)(xue)(xue)(xue)(xue)流,改善腦(nao)膜微循(xun)環(huan)(huan)障礙;可有(you)(you)(you)(you)效地抑(yi)(yi)制(zhi)腦(nao)缺(que)血(xue)(xue)(xue)(xue)(xue)(xue)時(shi)體(ti)內(nei)(nei)血(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)板激活,糾正循(xun)環(huan)(huan)中(zhong)(zhong)(zhong)花(hua)生四(si)烯酸(suan)主要代謝產(chan)物的(de)(de)(de)平衡失(shi)調(diao)(diao),抑(yi)(yi)制(zhi)缺(que)血(xue)(xue)(xue)(xue)(xue)(xue)后血(xue)(xue)(xue)(xue)(xue)(xue)漿β血(xue)(xue)(xue)(xue)(xue)(xue)栓球(qiu)蛋白(βTG)、血(xue)(xue)(xue)(xue)(xue)(xue)小(xiao)板因子(zi)4(PF4)和(he)血(xue)(xue)(xue)(xue)(xue)(xue)栓烷B2(TXB2)的(de)(de)(de)升高(gao),使(shi)(shi)腦(nao)缺(que)血(xue)(xue)(xue)(xue)(xue)(xue)后血(xue)(xue)(xue)(xue)(xue)(xue)漿和(he)腦(nao)脊(ji)液(ye)中(zhong)(zhong)(zhong)強啡肽AI13含(han)量(liang)降低(di),因而對(dui)(dui)(dui)(dui)(dui)腦(nao)缺(que)血(xue)(xue)(xue)(xue)(xue)(xue)性損害有(you)(you)(you)(you)改善和(he)防(fang)治作(zuo)用(yong)(yong)(yong)(yong),對(dui)(dui)(dui)(dui)(dui)腦(nao)水腫有(you)(you)(you)(you)一(yi)定(ding)治療作(zuo)用(yong)(yong)(yong)(yong);川芎(xiong)揮發油少量(liang)對(dui)(dui)(dui)(dui)(dui)大腦(nao)活動(dong)有(you)(you)(you)(you)抑(yi)(yi)制(zhi)作(zuo)用(yong)(yong)(yong)(yong),而對(dui)(dui)(dui)(dui)(dui)延腦(nao)呼(hu)吸(xi)(xi)中(zhong)(zhong)(zhong)樞(shu)、血(xue)(xue)(xue)(xue)(xue)(xue)管運動(dong)中(zhong)(zhong)(zhong)樞(shu)和(he)脊(ji)髓反(fan)射(she)中(zhong)(zhong)(zhong)樞(shu)機能(neng)(neng)也有(you)(you)(you)(you)興(xing)奮作(zuo)用(yong)(yong)(yong)(yong);大劑(ji)(ji)量(liang)對(dui)(dui)(dui)(dui)(dui)大腦(nao)及(ji)腦(nao)干的(de)(de)(de)抑(yi)(yi)制(zhi)作(zuo)用(yong)(yong)(yong)(yong)加(jia)深,以致延腦(nao)各中(zhong)(zhong)(zhong)樞(shu)和(he)脊(ji)髓反(fan)射(she)機能(neng)(neng)受抑(yi)(yi)制(zhi);川芎(xiong)煎劑(ji)(ji)能(neng)(neng)使(shi)(shi)戊巴比(bi)妥鈉(na)引(yin)起的(de)(de)(de)睡(shui)眠(mian)時(shi)間延長,并能(neng)(neng)拮(jie)抗(kang)咖(ka)啡因的(de)(de)(de)興(xing)奮作(zuo)用(yong)(yong)(yong)(yong);可降低(di)卵巢內(nei)(nei)PGE2含(han)量(liang),降低(di)假孕大鼠血(xue)(xue)(xue)(xue)(xue)(xue)中(zhong)(zhong)(zhong)孕酮含(han)量(liang),抑(yi)(yi)制(zhi)卵巢HCG/LH受體(ti)特異結合:所(suo)含(han)阿魏(wei)酸(suan)對(dui)(dui)(dui)(dui)(dui)免(mian)疫(yi)系(xi)統(tong)具有(you)(you)(you)(you)一(yi)定(ding)調(diao)(diao)整作(zuo)用(yong)(yong)(yong)(yong),可提高(gao)γ球(qiu)蛋白及(ji)T淋(lin)巴細(xi)胞;對(dui)(dui)(dui)(dui)(dui)60Co、γ射(she)線及(ji)氮(dan)芥所(suo)形成(cheng)的(de)(de)(de)損傷有(you)(you)(you)(you)明(ming)顯的(de)(de)(de)保護作(zuo)用(yong)(yong)(yong)(yong),通過免(mian)疫(yi)調(diao)(diao)整可反(fan)射(she)性調(diao)(diao)節(jie)神(shen)經(jing)(jing)、內(nei)(nei)分泌功(gong)能(neng)(neng);川藥(yao)嗪能(neng)(neng)增(zeng)強單核及(ji)巨(ju)噬(shi)細(xi)胞吞噬(shi)功(gong)能(neng)(neng),提高(gao)淋(lin)巴細(xi)胞轉化率及(ji)ANAE檢測的(de)(de)(de)陽性百分率,促進SRBC抗(kang)體(ti)的(de)(de)(de)形成(cheng)。梔子(zi)醇提取物有(you)(you)(you)(you)鎮(zhen)(zhen)(zhen)靜(jing)、解(jie)熱(re)(re)和(he)鎮(zhen)(zhen)(zhen)痛(tong)作(zuo)用(yong)(yong)(yong)(yong)。同(tong)時(shi)該方劑(ji)(ji)中(zhong)(zhong)(zhong)蒼(cang)術(shu)含(han)復合維(wei)生素(su)B,川芎(xiong)含(han)有(you)(you)(you)(you)維(wei)生素(su)A、葉酸(suan),神(shen)曲含(han)大量(liang)維(wei)生素(su)B復合體(ti),這些維(wei)生素(su)對(dui)(dui)(dui)(dui)(dui)神(shen)經(jing)(jing)、內(nei)(nei)分泌功(gong)能(neng)(neng)也具有(you)(you)(you)(you)營養和(he)調(diao)(diao)節(jie)功(gong)能(neng)(neng)。
4.9.4對心(xin)(xin)臟(zang)、血(xue)(xue)管、血(xue)(xue)液(ye)流變學的(de)(de)影響(xiang) 君(jun)藥香(xiang)附所含總(zong)(zong)生(sheng)物(wu)堿、苷(gan)類、黃(huang)酮(tong)類、酚(fen)類化(hua)合物(wu)的(de)(de)水(shui)溶液(ye)有強心(xin)(xin)及降(jiang)(jiang)(jiang)低(di)血(xue)(xue)壓(ya)的(de)(de)作(zuo)用。臣藥蒼(cang)術可(ke)降(jiang)(jiang)(jiang)低(di)心(xin)(xin)肌(ji)細(xi)胞(bao)(bao)的(de)(de)自律(lv)(lv)性(xing),延長不應期,保護(hu)心(xin)(xin)肌(ji)細(xi)胞(bao)(bao)膜上的(de)(de)Na+K+ATP酶的(de)(de)功能(neng)(neng)而具有顯著(zhu)抗(kang)心(xin)(xin)律(lv)(lv)失常作(zuo)用。川(chuan)(chuan)芎煎劑(ji)(ji)能(neng)(neng)增加(jia)心(xin)(xin)肌(ji)收縮(suo)力,抗(kang)心(xin)(xin)律(lv)(lv)失常,川(chuan)(chuan)芎及其(qi)提(ti)取(qu)物(wu)能(neng)(neng)顯著(zhu)擴張(zhang)(zhang)冠狀動脈,增加(jia)冠脈血(xue)(xue)流,降(jiang)(jiang)(jiang)低(di)心(xin)(xin)肌(ji)耗氧量,川(chuan)(chuan)芎嗪是(shi)α1受體(ti)阻(zu)滯劑(ji)(ji),能(neng)(neng)增加(jia)心(xin)(xin)肌(ji)內(nei)cAMP水(shui)平,抑(yi)制Ca2+內(nei)流,減(jian)輕(qing)心(xin)(xin)肌(ji)細(xi)胞(bao)(bao)內(nei)Ca2+超(chao)載,減(jian)少心(xin)(xin)肌(ji)缺血(xue)(xue)時細(xi)胞(bao)(bao)凋亡(wang);川(chuan)(chuan)芎嗪注射液(ye)能(neng)(neng)增加(jia)機體(ti)內(nei)源性(xing)SOD活(huo)性(xing),降(jiang)(jiang)(jiang)低(di)MDA水(shui)平,對失血(xue)(xue)性(xing)休克再灌注損(sun)(sun)傷有防(fang)治(zhi)作(zuo)用;并能(neng)(neng)對抗(kang)垂體(ti)后(hou)葉素引起(qi)的(de)(de)心(xin)(xin)肌(ji)缺血(xue)(xue);川(chuan)(chuan)芎嗪及川(chuan)(chuan)芎總(zong)(zong)堿能(neng)(neng)擴張(zhang)(zhang)血(xue)(xue)管,降(jiang)(jiang)(jiang)低(di)血(xue)(xue)壓(ya),可(ke)顯著(zhu)改善微循環,同(tong)時能(neng)(neng)顯著(zhu)抑(yi)制血(xue)(xue)小板聚集,抗(kang)血(xue)(xue)栓形成,降(jiang)(jiang)(jiang)低(di)血(xue)(xue)脂(zhi)和抗(kang)動脈硬化(hua)。梔子(zi)提(ti)取(qu)物(wu)則對心(xin)(xin)肌(ji)收縮(suo)力、心(xin)(xin)輸出量有抑(yi)制作(zuo)用,大劑(ji)(ji)量可(ke)引起(qi)心(xin)(xin)肌(ji)損(sun)(sun)害,梔子(zi)煎劑(ji)(ji)能(neng)(neng)防(fang)止動脈粥樣硬化(hua),通過增強延髓副交感神經中樞緊張(zhang)(zhang)度而發揮持久(jiu)的(de)(de)降(jiang)(jiang)(jiang)血(xue)(xue)壓(ya)作(zuo)用。
4.9.5對子(zi)(zi)宮(gong)的(de)作用(yong)(yong) 君藥香(xiang)(xiang)附對子(zi)(zi)宮(gong)有(you)抑(yi)制(zhi)作用(yong)(yong),使(shi)(shi)其肌張力降低、收縮(suo)力減弱(ruo),使(shi)(shi)子(zi)(zi)宮(gong)平滑肌松弛,其所含α香(xiang)(xiang)附酮不僅能(neng)抑(yi)制(zhi)未孕子(zi)(zi)宮(gong)自(zi)發性收縮(suo),同(tong)時(shi)能(neng)抑(yi)制(zhi)縮(suo)宮(gong)素(su)(su)引起(qi)的(de)子(zi)(zi)宮(gong)收縮(suo),有(you)雌(ci)激素(su)(su)樣作用(yong)(yong)。而川芎浸膏(gao)可(ke)使(shi)(shi)子(zi)(zi)宮(gong)收縮(suo)增強,直至攣縮(suo),大(da)劑量反使(shi)(shi)子(zi)(zi)宮(gong)麻痹(bi)。二者對子(zi)(zi)宮(gong)的(de)作用(yong)(yong)究竟誰(shui)占優勢(shi),是(shi)產生收縮(suo)還是(shi)抑(yi)制(zhi)收縮(suo),從本方劑能(neng)治(zhi)療(liao)(liao)痛(tong)經來看,推(tui)測(ce)乃川芎劑量較大(da)時(shi)則產生抑(yi)制(zhi)收縮(suo)作用(yong)(yong),故可(ke)治(zhi)療(liao)(liao)婦(fu)女(nv)痛(tong)經。同(tong)時(shi)川芎嗪有(you)抗維(wei)生素(su)(su)E缺乏癥的(de)作用(yong)(yong),與香(xiang)(xiang)附均有(you)增強雌(ci)激素(su)(su)作用(yong)(yong),這(zhe)可(ke)能(neng)是(shi)其治(zhi)療(liao)(liao)痛(tong)經和(he)月(yue)經不調的(de)機理(li)。
4.9.6抗(kang)炎(yan)、抗(kang)氧(yang)(yang)(yang)化作(zuo)(zuo)用 君藥(yao)香附有(you)(you)(you)抗(kang)炎(yan)作(zuo)(zuo)用。臣藥(yao)蒼術丙酮提取(qu)(qu)物有(you)(you)(you)較強的(de)(de)抗(kang)缺氧(yang)(yang)(yang)能(neng)力(li),蒼術的(de)(de)某些化合物對(dui)5脂氧(yang)(yang)(yang)化酶(5LOX)、環氧(yang)(yang)(yang)化酶1(COX1)有(you)(you)(you)很強的(de)(de)抑(yi)(yi)制(zhi)作(zuo)(zuo)用,表現出抗(kang)氧(yang)(yang)(yang)化作(zuo)(zuo)用。梔子也有(you)(you)(you)抗(kang)炎(yan)作(zuo)(zuo)用,梔子提取(qu)(qu)物對(dui)炎(yan)癥的(de)(de)毛細血管通透性提高、滲出、水腫(zhong)、肉芽組織增生等炎(yan)癥的(de)(de)各個階(jie)段均有(you)(you)(you)抑(yi)(yi)制(zhi)作(zuo)(zuo)用。川芎(xiong)所含(han)阿魏酸鈉對(dui)DMN釋放的(de)(de)自(zi)(zi)由基(ji)有(you)(you)(you)明(ming)顯的(de)(de)清除作(zuo)(zuo)用,對(dui)水溶液(ye)體產生的(de)(de)超氧(yang)(yang)(yang)陰離子和(he)羥自(zi)(zi)由基(ji)有(you)(you)(you)明(ming)顯的(de)(de)清除作(zuo)(zuo)用,同時有(you)(you)(you)直接捕獲(huo)自(zi)(zi)由基(ji)的(de)(de)作(zuo)(zuo)用,還有(you)(you)(you)抑(yi)(yi)制(zhi)結締(di)組織增生等抗(kang)炎(yan)作(zuo)(zuo)用。
2.《刪補名醫方論》:以(yi)(yi)氣(qi)為(wei)本,若(ruo)飲食(shi)不(bu)節(jie),寒溫不(bu)適,喜怒無常(chang),憂思無度,使沖(chong)和之氣(qi)升降失(shi)常(chang),以(yi)(yi)致胃郁(yu)(yu)不(bu)思飲食(shi),脾郁(yu)(yu)不(bu)消水谷,氣(qi)郁(yu)(yu)胸(xiong)腹脹滿(man),血(xue)郁(yu)(yu)胸(xiong)膈(ge)刺(ci)痛,濕郁(yu)(yu)痰(tan)飲,火(huo)郁(yu)(yu)為(wei)熱,及嘔吐、惡心,吞酸、吐酸、嘈雜、噯(ai)氣(qi),百病叢生。故用(yong)香附(fu)以(yi)(yi)開氣(qi)郁(yu)(yu),蒼術以(yi)(yi)除濕郁(yu)(yu),撫芎以(yi)(yi)行血(xue)郁(yu)(yu),山梔以(yi)(yi)清火(huo)郁(yu)(yu),神曲以(yi)(yi)消食(shi)郁(yu)(yu)。五藥相(xiang)須,共收疏解(jie)五郁(yu)(yu)之效。
5《口齒類要》方之越鞠丸人體體表面積計算器BMI指數計算及評價女性安全期計算器預產期計算器孕期體重增長正常值孕期用藥安全性分級(FDA)五行八字成人血壓評價體溫水平評價糖尿病飲食建議臨床生化常用單位換算基礎代謝率計算補鈉計算器補鐵計算器處方常用拉丁文縮寫速查藥代動力學常用符號速查有效血漿滲透壓計算器乙醇攝入量計算器
醫學百科,馬上計算!
6《女科切要》卷二方之越鞠丸
7越鞠丸的藥典標準
Yueju Wan
(2)取(qu)本品(pin)(pin)3g,研碎,加乙(yi)醚30ml,加熱回流1小時,放冷,濾(lv)過(guo),藥(yao)(yao)渣備用,濾(lv)液(ye)揮去乙(yi)醚,殘(can)渣加乙(yi)酸乙(yi)酯1ml使溶解,作為供(gong)試(shi)品(pin)(pin)溶液(ye)。另(ling)取(qu)蒼術(shu)對照(zhao)藥(yao)(yao)材(cai)(cai)0.5g,同法制(zhi)成對照(zhao)藥(yao)(yao)材(cai)(cai)溶液(ye)。照(zhao)薄(bo)層(ceng)色(se)譜(pu)法(2010年版(ban)藥(yao)(yao)典一部附錄Ⅵ B)試(shi)驗,吸(xi)取(qu)上述兩種溶液(ye)各5~10μl,分別點于同一硅膠G薄(bo)層(ceng)板上,以石(shi)油醚(60~90℃)為展(zhan)開劑(ji),展(zhan)開,取(qu)出,晾干,噴以5%對二甲氨基苯甲醛的10%硫酸乙(yi)醇溶液(ye),加熱至斑點顯色(se)清晰。供(gong)試(shi)品(pin)(pin)色(se)譜(pu)中,在與對照(zhao)藥(yao)(yao)材(cai)(cai)色(se)譜(pu)相應的位置(zhi)上,顯相同的深(shen)綠色(se)斑點。
(3)取(qu)川芎對照(zhao)藥材(cai)0.5g,按[鑒別](2)項下(xia)的供試(shi)(shi)(shi)品溶(rong)(rong)液(ye)(ye)(ye)制備方法制成對照(zhao)藥材(cai)溶(rong)(rong)液(ye)(ye)(ye)。照(zhao)薄(bo)層色(se)譜法(2010年版藥典一部附錄Ⅵ B)試(shi)(shi)(shi)驗,吸取(qu)[鑒別](2)項下(xia)的供試(shi)(shi)(shi)品溶(rong)(rong)液(ye)(ye)(ye)與上(shang)述對照(zhao)藥材(cai)溶(rong)(rong)液(ye)(ye)(ye)各(ge)5μl,分別點于同(tong)一硅膠G薄(bo)層板(ban)上(shang),以(yi)正己烷-乙酸乙酯(9:1)為(wei)展開劑,展開,取(qu)出,晾干,置紫外光燈(deng)(365nm)下(xia)檢視(shi)。供試(shi)(shi)(shi)品色(se)譜中,在與對照(zhao)藥材(cai)色(se)譜相(xiang)應的位置上(shang),顯相(xiang)同(tong)顏(yan)色(se)的熒光斑(ban)點。
(4)取(qu)(qu)[鑒(jian)別](2)項(xiang)下(xia)乙(yi)(yi)醚回流提取(qu)(qu)后的(de)藥(yao)渣,揮盡(jin)乙(yi)(yi)醚,加(jia)乙(yi)(yi)酸(suan)(suan)乙(yi)(yi)酯30ml,加(jia)熱(re)回流1小時(shi),放冷,濾(lv)過,濾(lv)液(ye)蒸干(gan)(gan),殘渣加(jia)甲(jia)醇3ml使(shi)溶解,濾(lv)過,濾(lv)液(ye)作為(wei)供(gong)試品(pin)(pin)溶液(ye)。另(ling)取(qu)(qu)梔子苷對(dui)照品(pin)(pin),加(jia)甲(jia)醇制成每1ml含1mg的(de)溶液(ye),作為(wei)對(dui)照品(pin)(pin)溶液(ye)。照薄層(ceng)色(se)譜法(2010年版(ban)藥(yao)典(dian)一部附錄Ⅵ B)試驗(yan),吸取(qu)(qu)上(shang)述兩種溶液(ye)各5μl,分別點(dian)于同(tong)一硅膠G薄層(ceng)板上(shang),以乙(yi)(yi)酸(suan)(suan)乙(yi)(yi)酯-丙酮-甲(jia)酸(suan)(suan)-水(20:14:4:1)為(wei)展(zhan)開(kai)劑,展(zhan)開(kai),取(qu)(qu)出,晾干(gan)(gan),噴以10%硫酸(suan)(suan)乙(yi)(yi)醇溶液(ye),在105℃加(jia)熱(re)至斑(ban)點(dian)顯(xian)色(se)清晰。供(gong)試品(pin)(pin)色(se)譜中,在與(yu)對(dui)照品(pin)(pin)色(se)譜相應的(de)位置上(shang),顯(xian)相同(tong)顏色(se)的(de)斑(ban)點(dian)。
7.7.1色譜(pu)條(tiao)件與系統適(shi)用性試驗 以十(shi)八烷基硅(gui)烷鍵合(he)硅(gui)膠為(wei)填(tian)充(chong)劑;以乙(yi)腈-水(shui)-磷酸(9:91:0.1)為(wei)流動相(xiang),檢測波長為(wei)240nm。理論板數按梔(zhi)子苷峰計算應(ying)不低于(yu)3000。
7.7.2對照品溶(rong)液(ye)的制備 取梔子苷對照品適量,精密稱定,加50%甲(jia)醇制成每(mei)1ml含25μg的溶(rong)液(ye),即(ji)得(de)。
7.7.3供試(shi)品溶液(ye)的制備 取本品適量(liang),研細,取約0.1g,精(jing)密(mi)(mi)稱定,置具塞錐形瓶中,精(jing)密(mi)(mi)加入(ru)50%甲醇50ml.密(mi)(mi)塞,稱定重(zhong)量(liang),超聲處理(功率150W,頻(pin)率25kHz)30分鐘,放(fang)冷,再(zai)稱定重(zhong)量(liang),用50%甲醇補(bu)足減失的重(zhong)量(liang),搖勻,濾過,取續濾液(ye),即(ji)得。
7.7.4測(ce)定法 分別(bie)精(jing)密吸取對照(zhao)品(pin)溶(rong)液與供試品(pin)溶(rong)液各20μl,注入液相色(se)譜儀,測(ce)定,即得。
本(ben)品(pin)每(mei)1g含炒梔子以梔子苷(C17H24O10)計,不(bu)得少(shao)于5.0mg。
8越鞠丸藥品說明書
2.服藥期間(jian)要保(bao)持(chi)情緒樂觀,切忌(ji)生氣惱(nao)怒。
3.有高血壓、心臟病(bing)、肝病(bing)、糖尿病(bing)、腎(shen)病(bing)等慢性病(bing)嚴重者應在(zai)醫師指導下服用。
4.兒童、孕婦、哺(bu)乳期婦女、年老(lao)體(ti)弱者應(ying)在(zai)醫師指導下服用。
5.服藥3天(tian)癥狀無緩(huan)解(jie),應(ying)去醫院就診(zhen)。
6.對越鞠丸過(guo)敏(min)者(zhe)禁用(yong)(yong),過(guo)敏(min)體質者(zhe)慎用(yong)(yong)。
7.越(yue)鞠丸性狀發生改(gai)變時禁(jin)止使用。
8.兒童(tong)必須在(zai)成(cheng)人(ren)監(jian)護下使(shi)用。
9.請將(jiang)越鞠丸放在兒童不能接(jie)觸的(de)地(di)方。
10.如正在使用其他藥品,使用越鞠丸前請(qing)咨詢(xun)醫師(shi)(shi)或(huo)藥師(shi)(shi)。
1 柴胡舒肝丸
主要成分有白芍、檳榔、柴胡等成分,主要功效是疏肝理氣,消脹止痛,常用來調理肝氣不舒,胸悶,消化不良,食欲不振,甚至是嘔吐,反酸等癥狀,使用期間,要保持心情的樂觀開朗,避免肝氣郁結
2 開郁舒肝丸
主要成分有香附,莪術,木香,檳榔,烏藥枳殼、大黃等多種藥材,這些藥材有疏肝順氣的功效,主要作用是開郁、舒肝、順氣、止痛,常用來調理肝氣瘀滯所導致的胸悶,胸痛,腹脹等癥狀
3 丹梔逍遙丸
主要成分有牡丹皮、白芍、白術、柴胡、梔子等,白芍、柴胡能夠疏理肝氣,加上牡丹皮、梔子又能清熱降火,所以丹梔逍遙丸有很好的順氣、疏肝解郁、清肝降火的功效,對肝郁氣滯導致的胸悶、口苦,甚至是食欲不振、肋痛、心情煩躁,都有很好的調理功效
女性因為肝氣不舒,而引起的月經不調,痛經,乳房脹痛等癥狀也能夠得到很好地改善
4 越鞠丸
主要成分有川穹、木香、梔子、香附、神曲等,川穹、木香能夠順氣通絡,香附、神曲能夠疏肝,所以說越鞠丸對于行氣止痛,疏肝解郁也有很好的效果,可以用于治療胸悶、腹脹、食欲不振、反酸、消化不良等癥狀
5 開郁老蔻丸
主要成分有神曲、半夏、無藥、枳殼、莪術、厚樸、三棱、檳榔等多種藥材,對于開胸順氣、疏肝解郁也有很好的效果,常用來調理肝郁氣滯所導致的脾胃失調、消化不良、嘔吐、腹瀉等問題
6 舒肝理氣丸
主要成分有柴胡、香附、半夏等,柴胡、香附、半夏等藥材具有疏肝的療效,所以說也能夠調理肝經淤堵所引起的結節問題
感謝關注@沈(shen)氏女科21代弟子 ,每天(tian)分(fen)享女性(xing) 健康(kang) 調養知識,歡迎(ying)大家轉發給(gei)更多有需要的人[比心][比心][比心]
決它們.那我將會相信我們的身邊會到處都充
滿著愛.
例如說老年人要過街,我們便可以去攙扶他(她),幫助這些老人一起過馬路.盲人在走路時,萬一
碰到什么東西,你便可以上前去提醒他(她)一聲:“老伯伯,你的前面有一個東西,小心撞到!”于是
,去當他(她)的拐杖,當他(她)的扶手.在過中秋節時,我們班的每一個同學都帶了一片心意—一個
月餅,然后由中隊長,班干部去敬老院分發給老人們,帶去我們的心意,讓敬老院的中秋節不再寂寞.還
有小朋友們,他(她)們有什么不懂的地方,你可以去把老師教授給(gei)你們
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